PTPRK report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008285Biological processnegative regulation of cell population proliferation
GO_0006470Biological processprotein dephosphorylation
GO_0034614Biological processcellular response to reactive oxygen species
GO_0045786Biological processnegative regulation of cell cycle
GO_0034644Biological processcellular response to UV
GO_0007165Biological processsignal transduction
GO_0007155Biological processcell adhesion
GO_0034394Biological processprotein localization to cell surface
GO_0010839Biological processnegative regulation of keratinocyte proliferation
GO_0048041Biological processfocal adhesion assembly
GO_0030336Biological processnegative regulation of cell migration
GO_0007179Biological processtransforming growth factor beta receptor signaling pathway
GO_0016477Biological processcell migration
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0031256Cellular componentleading edge membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005911Cellular componentcell-cell junction
GO_0009986Cellular componentcell surface
GO_0005912Cellular componentadherens junction
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0030054Cellular componentcell junction
GO_0005001Molecular functiontransmembrane receptor protein tyrosine phosphatase activity
GO_0019901Molecular functionprotein kinase binding
GO_0008013Molecular functionbeta-catenin binding
GO_0045295Molecular functiongamma-catenin binding
GO_0005515Molecular functionprotein binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene namePTPRK
Protein nameReceptor-type tyrosine-protein phosphatase F
Protein tyrosine phosphatase receptor type K (Receptor-type tyrosine-protein phosphatase kappa)
Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)
PTPRK protein (Protein tyrosine phosphatase receptor type K) (Receptor-type tyrosine-protein phosphatase kappa)
protein-tyrosine-phosphatase (EC 3.1.3.48)
SynonymsPTPK
DescriptionFUNCTION: Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa. .

AccessionsH0Y6P5
ENST00000625418.1
ENST00000392449.4
ENST00000415055.2
ENST00000532751.1
ENST00000628824.1
E9PRW2
ENST00000628472.1
ENST00000627768.1
ENST00000628245.2
ENST00000532331.5 [Q15262-4]
ENST00000625615.2
E9PMV4
ENST00000628183.2 [Q15262-1]
ENST00000368210.7
ENST00000368215.7 [Q15262-1]
A0A0G2JQF6
H0YD44
Q6P493
ENST00000619256.4 [Q15262-4]
ENST00000490332.2
ENST00000368213.9 [Q15262-3]
Q86WJ2
ENST00000618924.4 [Q15262-2]
ENST00000618215.3 [Q15262-3]
ENST00000625760.2
E9PGC5
ENST00000531050.5
H0Y6V4
Q5TG12
ENST00000525459.1
ENST00000415046.6
ENST00000621720.2
H0YDP9
ENST00000626594.2
ENST00000368207.7
Q15262
ENST00000368226.9 [Q15262-2]