Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 33 studies | 42% ± 18% | |
pericyte | 18 studies | 44% ± 24% | |
fibroblast | 16 studies | 37% ± 15% | |
smooth muscle cell | 13 studies | 38% ± 16% | |
epithelial cell | 13 studies | 36% ± 14% | |
basal cell | 12 studies | 36% ± 21% | |
oligodendrocyte | 12 studies | 80% ± 11% | |
astrocyte | 12 studies | 43% ± 19% | |
oligodendrocyte precursor cell | 11 studies | 50% ± 16% | |
glutamatergic neuron | 10 studies | 54% ± 25% | |
adipocyte | 10 studies | 30% ± 10% | |
ciliated cell | 8 studies | 40% ± 18% | |
endothelial cell of lymphatic vessel | 8 studies | 53% ± 14% | |
secretory cell | 7 studies | 24% ± 5% | |
neuron | 7 studies | 52% ± 19% | |
type I pneumocyte | 7 studies | 52% ± 16% | |
type II pneumocyte | 7 studies | 58% ± 22% | |
GABAergic neuron | 6 studies | 45% ± 22% | |
club cell | 6 studies | 52% ± 25% | |
capillary endothelial cell | 6 studies | 34% ± 16% | |
cardiac muscle cell | 6 studies | 59% ± 21% | |
endothelial cell of vascular tree | 6 studies | 35% ± 20% | |
hepatocyte | 5 studies | 64% ± 24% | |
microglial cell | 5 studies | 50% ± 21% | |
endothelial cell of artery | 5 studies | 23% ± 8% | |
mesothelial cell | 5 studies | 47% ± 16% | |
myofibroblast cell | 5 studies | 34% ± 14% | |
respiratory goblet cell | 4 studies | 50% ± 25% | |
cholangiocyte | 4 studies | 77% ± 11% | |
interneuron | 4 studies | 51% ± 10% | |
progenitor cell | 4 studies | 44% ± 17% | |
luminal cell of prostate epithelium | 4 studies | 29% ± 13% | |
hepatic stellate cell | 3 studies | 49% ± 21% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 58% ± 13% | |
granule cell | 3 studies | 44% ± 27% | |
amacrine cell | 3 studies | 32% ± 19% | |
vein endothelial cell | 3 studies | 45% ± 22% | |
GABAergic amacrine cell | 3 studies | 54% ± 9% | |
abnormal cell | 3 studies | 38% ± 26% | |
retinal pigment epithelial cell | 3 studies | 46% ± 16% | |
pancreatic ductal cell | 3 studies | 52% ± 22% | |
connective tissue cell | 3 studies | 32% ± 15% | |
muscle cell | 3 studies | 26% ± 5% | |
goblet cell | 3 studies | 42% ± 34% | |
mucus secreting cell | 3 studies | 51% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2830.84 | 1444 / 1445 | 99% | 59.57 | 182 / 183 |
lung | 100% | 3660.09 | 578 / 578 | 99% | 37.99 | 1145 / 1155 |
intestine | 100% | 4267.97 | 966 / 966 | 99% | 44.33 | 520 / 527 |
prostate | 100% | 3456.84 | 245 / 245 | 99% | 33.68 | 495 / 502 |
stomach | 100% | 4675.63 | 359 / 359 | 99% | 48.80 | 282 / 286 |
pancreas | 100% | 3547.10 | 328 / 328 | 98% | 43.89 | 175 / 178 |
uterus | 100% | 2876.76 | 170 / 170 | 97% | 32.86 | 443 / 459 |
kidney | 100% | 2009.34 | 89 / 89 | 96% | 37.35 | 866 / 901 |
bladder | 100% | 4041.71 | 21 / 21 | 96% | 32.98 | 482 / 504 |
breast | 100% | 4332.79 | 459 / 459 | 95% | 50.61 | 1067 / 1118 |
liver | 100% | 2634.44 | 226 / 226 | 94% | 23.61 | 382 / 406 |
thymus | 100% | 2546.42 | 652 / 653 | 94% | 19.52 | 568 / 605 |
brain | 98% | 2580.17 | 2581 / 2642 | 95% | 21.01 | 673 / 705 |
ovary | 100% | 3463.79 | 180 / 180 | 87% | 16.23 | 376 / 430 |
skin | 100% | 3615.26 | 1809 / 1809 | 57% | 8.84 | 270 / 472 |
adrenal gland | 88% | 985.32 | 227 / 258 | 63% | 15.02 | 145 / 230 |
adipose | 100% | 2821.66 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3937.09 | 1335 / 1335 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 9.30 | 1 / 1 |
spleen | 99% | 1276.85 | 238 / 241 | 0% | 0 | 0 / 0 |
heart | 98% | 2145.66 | 846 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 32.69 | 43 / 45 |
muscle | 92% | 931.39 | 735 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 20% | 4.00 | 16 / 80 |
peripheral blood | 7% | 71.98 | 64 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0034614 | Biological process | cellular response to reactive oxygen species |
GO_0045786 | Biological process | negative regulation of cell cycle |
GO_0034644 | Biological process | cellular response to UV |
GO_0007165 | Biological process | signal transduction |
GO_0007155 | Biological process | cell adhesion |
GO_0034394 | Biological process | protein localization to cell surface |
GO_0010839 | Biological process | negative regulation of keratinocyte proliferation |
GO_0048041 | Biological process | focal adhesion assembly |
GO_0030336 | Biological process | negative regulation of cell migration |
GO_0007179 | Biological process | transforming growth factor beta receptor signaling pathway |
GO_0016477 | Biological process | cell migration |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0031256 | Cellular component | leading edge membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005911 | Cellular component | cell-cell junction |
GO_0009986 | Cellular component | cell surface |
GO_0005912 | Cellular component | adherens junction |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0030054 | Cellular component | cell junction |
GO_0005001 | Molecular function | transmembrane receptor protein tyrosine phosphatase activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0008013 | Molecular function | beta-catenin binding |
GO_0045295 | Molecular function | gamma-catenin binding |
GO_0005515 | Molecular function | protein binding |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
Gene name | PTPRK |
Protein name | Receptor-type tyrosine-protein phosphatase F Protein tyrosine phosphatase receptor type K (Receptor-type tyrosine-protein phosphatase kappa) Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48) PTPRK protein (Protein tyrosine phosphatase receptor type K) (Receptor-type tyrosine-protein phosphatase kappa) protein-tyrosine-phosphatase (EC 3.1.3.48) |
Synonyms | PTPK |
Description | FUNCTION: Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa. . |
Accessions | H0Y6P5 ENST00000625418.1 ENST00000392449.4 ENST00000415055.2 ENST00000532751.1 ENST00000628824.1 E9PRW2 ENST00000628472.1 ENST00000627768.1 ENST00000628245.2 ENST00000532331.5 [Q15262-4] ENST00000625615.2 E9PMV4 ENST00000628183.2 [Q15262-1] ENST00000368210.7 ENST00000368215.7 [Q15262-1] A0A0G2JQF6 H0YD44 Q6P493 ENST00000619256.4 [Q15262-4] ENST00000490332.2 ENST00000368213.9 [Q15262-3] Q86WJ2 ENST00000618924.4 [Q15262-2] ENST00000618215.3 [Q15262-3] ENST00000625760.2 E9PGC5 ENST00000531050.5 H0Y6V4 Q5TG12 ENST00000525459.1 ENST00000415046.6 ENST00000621720.2 H0YDP9 ENST00000626594.2 ENST00000368207.7 Q15262 ENST00000368226.9 [Q15262-2] |