FRMD4B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090162Biological processestablishment of epithelial cell polarity
GO_0001726Cellular componentruffle
GO_0005615Cellular componentextracellular space
GO_0005856Cellular componentcytoskeleton
GO_0005912Cellular componentadherens junction
GO_0005737Cellular componentcytoplasm
GO_0005923Cellular componentbicellular tight junction

IV. Literature review

[source]
Gene nameFRMD4B
Protein nameFERM domain-containing protein 4B (GRP1-binding protein GRSP1)
FRMD4B protein
FERM domain containing 4B
SynonymsGRSP1
KIAA1013
DescriptionFUNCTION: Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization. .

AccessionsQ6PEW6
C9JA15
Q2TB00
ENST00000473029.5
C9J6Q2
Q9Y2L6
ENST00000478263.5
ENST00000462512.1
ENST00000459638.5
ENST00000460709.5
H7C550
C9JYK2
C9JBX2
ENST00000398540.8 [Q9Y2L6-1]
E9PGA7
C9JAW0
C9J7M5
ENST00000497880.5
ENST00000493880.5
ENST00000489817.1