FLOT2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0098937Biological processanterograde dendritic transport
GO_0008544Biological processepidermis development
GO_0072659Biological processprotein localization to plasma membrane
GO_0010629Biological processnegative regulation of gene expression
GO_1903905Biological processpositive regulation of establishment of T cell polarity
GO_0034114Biological processregulation of heterotypic cell-cell adhesion
GO_0007155Biological processcell adhesion
GO_0099072Biological processregulation of postsynaptic membrane neurotransmitter receptor levels
GO_0044860Biological processprotein localization to plasma membrane raft
GO_0043123Biological processpositive regulation of canonical NF-kappaB signal transduction
GO_0050821Biological processprotein stabilization
GO_1902992Biological processnegative regulation of amyloid precursor protein catabolic process
GO_0034139Biological processregulation of toll-like receptor 3 signaling pathway
GO_0045661Biological processregulation of myoblast differentiation
GO_0016324Cellular componentapical plasma membrane
GO_0098978Cellular componentglutamatergic synapse
GO_0005886Cellular componentplasma membrane
GO_0031410Cellular componentcytoplasmic vesicle
GO_0030139Cellular componentendocytic vesicle
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0016020Cellular componentmembrane
GO_0002080Cellular componentacrosomal membrane
GO_0070062Cellular componentextracellular exosome
GO_0030864Cellular componentcortical actin cytoskeleton
GO_0044291Cellular componentcell-cell contact zone
GO_0016600Cellular componentflotillin complex
GO_0005925Cellular componentfocal adhesion
GO_0005912Cellular componentadherens junction
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005768Cellular componentendosome
GO_0032839Cellular componentdendrite cytoplasm
GO_0030027Cellular componentlamellipodium
GO_0001931Cellular componenturopod
GO_0031982Cellular componentvesicle
GO_0005901Cellular componentcaveola
GO_0016323Cellular componentbasolateral plasma membrane
GO_0002020Molecular functionprotease binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFLOT2
Protein nameFlotillin
Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1)
SynonymsESA1
hCG_1998851
M17S1
DescriptionFUNCTION: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.

AccessionsJ3QLD9
K7EKW9
ENST00000465427.3
ENST00000580805.5
ENST00000586827.6
Q14254
K7EJ47
Q9BTI6
Q6FG43
J3QKZ4
ENST00000394906.6
ENST00000585169.6
E7EMK3
ENST00000394908.9