GO_0043123 | OmnibusX

positive regulation of canonical NF-kappaB signal transduction

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	CCL19-CCR7	CCL19_HUMAN - CCR7_HUMAN	Ligand-Receptor	Signaling by Chemokines
2	CCL21-CCR7	CCL21_HUMAN - CCR7_HUMAN	Ligand-Receptor	Signaling by Chemokines
3	CX3CL1-CX3CR1	X3CL1_HUMAN - CX3C1_HUMAN	Ligand-Receptor	Signaling by Chemokines
4	EDN1-EDNRA	EDN1_HUMAN - EDNRA_HUMAN	Ligand-Receptor	Signaling by Endothelin
5	EDN1-EDNRB	EDN1_HUMAN - EDNRB_HUMAN	Ligand-Receptor	Signaling by Endothelin
6	LTB-LTBR	TNFC_HUMAN - TNR3_HUMAN	Ligand-Receptor	Signaling by Lipoxin/Leukotriene
7	TNF-TNFRSF1A	TNFA_HUMAN - TNR1A_HUMAN	Ligand-Receptor	Signaling by Tumor necrosis factor
8	TNFSF10-TNFRSF10B	TNF10_HUMAN - TR10B_HUMAN	Ligand-Receptor	Signaling by Tumor necrosis factor

II. Literature review

Name	positive regulation of canonical NF-kappaB signal transduction
ID	GO_0043123
collection_id	Biological process
Exact synonym	activation of I-kappaB kinase/NF-kappaB cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of I-kappaB kinase/NF-kappaB signaling, up regulation of I-kappaB kinase/NF-kappaB cascade, up-regulation of I-kappaB kinase/NF-kappaB cascade, upregulation of I-kappaB kinase/NF-kappaB cascade
Description	Any process that activates or increases the frequency, rate or extent of a canonical NF-kappaB signaling cascade.
External URL
Genes	CCL19 FKBP1A C18orf32 SHARPIN MIB2 TERF2IP EDA2R IL1B INAVA PARP1 HTR2B FLNA F2RL1 CASP8 PYCARD ECT2 IKBKB HLA-DRB1 PRKCE AKAP13 CASP1 MALT1 IKBKG TRIM6 TRIM68 AJUBA LTBR TRAF2 APOL3 TMEM101 IL1A TRIM58 CARD16 TMEM9B TAB3 IRF3 PRL TNIP2 LITAF CX3CL1 LURAP1 TRADD ZDHHC13 TNFRSF19 RFPL4AL1 NUP62 MTDH FLOT2 CCL21 CLEC7A LIMS1 IFIT5 TLR8 GJA1 TLR3 GPRC5B S100A13 TICAM1 CXXC5 LAMTOR5 LPAR1 SLC35B2 BIRC3 CD36 TBK1 TRIM38 CD4 PRKCB NFAT5 SLC44A2 TNFSF10 CANT1 RELA ANKRD17 EDNRB TIFAB TRAF6 MAP3K3 TGFB1 CCDC22 LGALS1 TICAM2 RIPK2 UNC5CL ILK VAPA CFLAR DAB2IP BRD4 DHX36 ATP2C1 DDX21 NDFIP1 IKBKE IRAK1 NOD1 PPM1A RNF31 TRIM13 BCL10 PELI1 GOLT1B IRAK4 FADD CCR7 CHUK RFPL2 F2R XIAP PRKN PPP5C TRIM21 CX3CR1 TFG RFPL4A TRAF3IP2 CLEC4D TFRC HMOX1 TNFRSF1A TRIM32 RHOC LURAP1L NOD2 TRIM52 LGALS9 TAB2 SECTM1 FBXW11 S100B RBCK1 BIRC2 EDNRA ECM1 LRRC19 MID2 CD40 VEGFA CTH CD74 BST2 PRKD1 NDFIP2 TRIM34 TLR6 UBD DDX1 S100A4 S100A12 TIFA FASLG TRIM62 RBX1 REL UBE2N MAP3K7 EDAR TRIM25 TLR9 FLOT1 ADIPOQ JMJD8 CARD9 CARD11 TLR4 NEK6 PLK2 TNFRSF10B TSPAN6 RHOA GAPDH RIPK1 LTF TIRAP CASP10 TMEM106A TNFSF11 PINK1 DHX15 PLEKHG5 IRAK1BP1 PIM2 ABL1 MAS1 RFPL1 RFPL3 MAVS GPR89A CLEC6A TNF UBE2V1 EDN1 ALPK1 MYD88 CUL1 SLC20A1 TRIM22 CAV1 ROR1 SHISA5 MIER1 LTB ZDHHC17 TRIM8 TRAF5 TLR7 CC2D1A EDA PELI2 TRIM5 MUL1 TMED4 WLS