RFPL1 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of RFPL1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	75%	12.48	183 / 245	2%	0.03	10 / 502
spleen	61%	3.50	146 / 241	0%	0	0 / 0
liver	52%	4.36	118 / 226	0%	0	0 / 406
ovary	50%	2.16	90 / 180	0%	0.04	1 / 430
adrenal gland	49%	1.77	126 / 258	0%	0	0 / 230
brain	45%	1.73	1188 / 2642	0%	0	0 / 705
uterus	11%	0.28	19 / 170	0%	0	0 / 459
kidney	8%	0.24	7 / 89	0%	0	0 / 901
intestine	6%	0.13	56 / 966	0%	0	0 / 527
pancreas	5%	0.13	15 / 328	1%	0.02	2 / 178
breast	4%	0.18	20 / 459	0%	0	0 / 1118
peripheral blood	4%	0.10	40 / 929	0%	0	0 / 0
thymus	4%	0.10	27 / 653	0%	0	0 / 605
lung	4%	0.09	23 / 578	0%	0.00	1 / 1155
esophagus	4%	0.10	56 / 1445	0%	0	0 / 183
adipose	3%	0.08	35 / 1204	0%	0	0 / 0
blood vessel	3%	0.06	34 / 1335	0%	0	0 / 0
heart	2%	0.05	21 / 861	0%	0	0 / 0
skin	2%	0.06	44 / 1809	0%	0	0 / 472
stomach	2%	0.04	7 / 359	0%	0	0 / 286
muscle	1%	0.02	7 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bladder	0%	0	0 / 21	0%	0	0 / 504
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0000209	Biological process	protein polyubiquitination
GO_0045087	Biological process	innate immune response
GO_0032436	Biological process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO_0051782	Biological process	negative regulation of cell division
GO_0032880	Biological process	regulation of protein localization
GO_2001272	Biological process	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO_0051092	Biological process	positive regulation of NF-kappaB transcription factor activity
GO_0043123	Biological process	positive regulation of canonical NF-kappaB signal transduction
GO_0010508	Biological process	positive regulation of autophagy
GO_0010972	Biological process	negative regulation of G2/M transition of mitotic cell cycle
GO_0045930	Biological process	negative regulation of mitotic cell cycle
GO_0043065	Biological process	positive regulation of apoptotic process
GO_0046596	Biological process	regulation of viral entry into host cell
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0061630	Molecular function	ubiquitin protein ligase activity
GO_0042803	Molecular function	protein homodimerization activity
GO_0019901	Molecular function	protein kinase binding
GO_0046872	Molecular function	metal ion binding

Gene name	RFPL1
Protein name	Ret finger protein-like 1 (RING finger protein 78)
Synonyms	RNF78 RFPL1L
Description	FUNCTION: Negatively regulates the G2-M phase transition, possibly by promoting cyclin B1/CCNB1 and CDK1 proteasomal degradation and thereby preventing their accumulation during interphase. .
Accessions	ENST00000354373.2 O75677

RFPL1 report