CANT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030166Biological processproteoglycan biosynthetic process
GO_0043123Biological processpositive regulation of canonical NF-kappaB signal transduction
GO_1904724Cellular componenttertiary granule lumen
GO_1904813Cellular componentficolin-1-rich granule lumen
GO_0070062Cellular componentextracellular exosome
GO_0032580Cellular componentGolgi cisterna membrane
GO_0005576Cellular componentextracellular region
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane
GO_0035580Cellular componentspecific granule lumen
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0042803Molecular functionprotein homodimerization activity
GO_0004382Molecular functionGDP phosphatase activity
GO_0045134Molecular functionUDP phosphatase activity
GO_0005509Molecular functioncalcium ion binding
GO_0043262Molecular functionADP phosphatase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCANT1
Protein nameSoluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107)
Calcium activated nucleotidase 1
SynonymsSHAPY
DescriptionFUNCTION: Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP . Involved in proteoglycan synthesis . .

AccessionsK7EQD4
ENST00000588075.5
ENST00000590370.5
K7EKT2
ENST00000392446.10 [Q8WVQ1-1]
ENST00000592228.1
ENST00000591773.5 [Q8WVQ1-1]
K7EQT4
K7EN15
ENST00000586916.6
K7EIP9
K7EMT2
ENST00000302345.6 [Q8WVQ1-1]
ENST00000591811.1
ENST00000591625.5
ENST00000588611.5
ENST00000592033.5
Q8WVQ1
K7EKW6
ENST00000620915.4 [Q8WVQ1-1]