Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 24 studies | 25% ± 8% | |
| connective tissue cell | 7 studies | 23% ± 6% | |
| pericyte | 5 studies | 31% ± 10% | |
| squamous epithelial cell | 4 studies | 61% ± 26% | |
| epithelial cell | 4 studies | 34% ± 10% | |
| smooth muscle cell | 3 studies | 19% ± 1% | |
| endothelial cell | 3 studies | 23% ± 4% |
Insufficient scRNA-seq data for expression of ECM1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 100% | 5161.87 | 1805 / 1809 | 95% | 256.59 | 449 / 472 |
| esophagus | 100% | 42874.29 | 1438 / 1445 | 89% | 145.57 | 162 / 183 |
| breast | 96% | 3020.10 | 440 / 459 | 86% | 154.03 | 966 / 1118 |
| lung | 99% | 2945.85 | 575 / 578 | 80% | 63.54 | 920 / 1155 |
| intestine | 92% | 1789.28 | 890 / 966 | 83% | 59.11 | 440 / 527 |
| uterus | 96% | 4436.86 | 163 / 170 | 73% | 92.70 | 336 / 459 |
| bladder | 95% | 1858.95 | 20 / 21 | 62% | 40.15 | 311 / 504 |
| thymus | 93% | 1428.94 | 610 / 653 | 59% | 165.11 | 359 / 605 |
| adrenal gland | 95% | 1628.24 | 244 / 258 | 54% | 34.69 | 124 / 230 |
| stomach | 59% | 1037.74 | 213 / 359 | 78% | 39.92 | 222 / 286 |
| kidney | 93% | 1543.48 | 83 / 89 | 40% | 16.16 | 362 / 901 |
| prostate | 98% | 1959.79 | 239 / 245 | 14% | 3.47 | 70 / 502 |
| liver | 95% | 2047.11 | 215 / 226 | 14% | 5.06 | 57 / 406 |
| ovary | 59% | 947.75 | 107 / 180 | 41% | 20.39 | 178 / 430 |
| adipose | 100% | 4248.05 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| heart | 98% | 4221.87 | 845 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 95% | 2362.81 | 1270 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 147.03 | 42 / 45 |
| spleen | 93% | 1451.25 | 223 / 241 | 0% | 0 | 0 / 0 |
| pancreas | 3% | 45.49 | 11 / 328 | 88% | 101.13 | 156 / 178 |
| brain | 48% | 587.81 | 1265 / 2642 | 25% | 8.68 | 178 / 705 |
| eye | 0% | 0 | 0 / 0 | 43% | 43.29 | 34 / 80 |
| muscle | 24% | 249.17 | 196 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 17% | 3.61 | 5 / 29 |
| peripheral blood | 1% | 12.01 | 7 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0001525 | Biological process | angiogenesis |
| GO_0006954 | Biological process | inflammatory response |
| GO_0045766 | Biological process | positive regulation of angiogenesis |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0007165 | Biological process | signal transduction |
| GO_0030500 | Biological process | regulation of bone mineralization |
| GO_0002063 | Biological process | chondrocyte development |
| GO_0001938 | Biological process | positive regulation of endothelial cell proliferation |
| GO_0002828 | Biological process | regulation of type 2 immune response |
| GO_0010466 | Biological process | negative regulation of peptidase activity |
| GO_0031214 | Biological process | biomineral tissue development |
| GO_0043123 | Biological process | positive regulation of canonical NF-kappaB signal transduction |
| GO_0030502 | Biological process | negative regulation of bone mineralization |
| GO_0001503 | Biological process | ossification |
| GO_0001960 | Biological process | negative regulation of cytokine-mediated signaling pathway |
| GO_0003416 | Biological process | endochondral bone growth |
| GO_2000404 | Biological process | regulation of T cell migration |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0031089 | Cellular component | platelet dense granule lumen |
| GO_0005201 | Molecular function | extracellular matrix structural constituent |
| GO_0002020 | Molecular function | protease binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005134 | Molecular function | interleukin-2 receptor binding |
| Gene name | ECM1 |
| Protein name | Truncated extracellular matrix protein 1 ECM1 short variant Extracellular matrix protein 1 (Secretory component p85) |
| Synonyms | |
| Description | FUNCTION: Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. . |
| Accessions | ENST00000346569.6 [Q16610-2] ENST00000369049.8 [Q16610-4] C8CHS3 Q2QKP8 ENST00000369047.9 [Q16610-1] Q16610 |
