LTBR report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0006915Biological processapoptotic process
GO_0006955Biological processimmune response
GO_2001238Biological processpositive regulation of extrinsic apoptotic signaling pathway
GO_0071260Biological processcellular response to mechanical stimulus
GO_0043123Biological processpositive regulation of canonical NF-kappaB signal transduction
GO_0048534Biological processhematopoietic or lymphoid organ development
GO_0043011Biological processmyeloid dendritic cell differentiation
GO_0046330Biological processpositive regulation of JNK cascade
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0005515Molecular functionprotein binding
GO_0042802Molecular functionidentical protein binding

IV. Literature review

[source]
Gene nameLTBR
Protein nameTumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III)
Lymphotoxin beta receptor
SynonymsTNFRSF3
TNFR3
D12S370
TNFCR
DescriptionFUNCTION: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. .

AccessionsF5H627
ENST00000541102.1
ENST00000228918.9 [P36941-1]
Q75UT6
ENST00000536876.5
F5H6F8
F5H2E7
P36941
F5H1S5
ENST00000539925.5 [P36941-2]
ENST00000544454.5
ENST00000543190.5