Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 13 studies | 24% ± 6% | |
| macrophage | 13 studies | 21% ± 5% | |
| classical monocyte | 12 studies | 26% ± 8% | |
| fibroblast | 10 studies | 23% ± 7% | |
| basal cell | 9 studies | 23% ± 8% | |
| epithelial cell | 9 studies | 34% ± 16% | |
| pericyte | 8 studies | 19% ± 3% | |
| monocyte | 7 studies | 19% ± 3% | |
| non-classical monocyte | 7 studies | 22% ± 6% | |
| type I pneumocyte | 6 studies | 25% ± 6% | |
| conventional dendritic cell | 5 studies | 28% ± 13% | |
| capillary endothelial cell | 5 studies | 18% ± 2% | |
| vein endothelial cell | 5 studies | 17% ± 2% | |
| secretory cell | 4 studies | 20% ± 6% | |
| myeloid cell | 4 studies | 25% ± 6% | |
| endothelial cell of lymphatic vessel | 4 studies | 19% ± 3% | |
| myofibroblast cell | 4 studies | 21% ± 3% | |
| ciliated cell | 4 studies | 24% ± 5% | |
| abnormal cell | 4 studies | 25% ± 9% | |
| endothelial cell of vascular tree | 4 studies | 18% ± 1% | |
| dendritic cell | 4 studies | 37% ± 13% | |
| goblet cell | 4 studies | 23% ± 8% | |
| connective tissue cell | 4 studies | 25% ± 13% | |
| pancreatic A cell | 3 studies | 27% ± 4% | |
| smooth muscle cell | 3 studies | 19% ± 2% | |
| enterocyte | 3 studies | 17% ± 2% | |
| enteroendocrine cell | 3 studies | 17% ± 1% | |
| endothelial cell of artery | 3 studies | 17% ± 1% | |
| microglial cell | 3 studies | 22% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 4828.71 | 328 / 328 | 100% | 88.78 | 178 / 178 |
| lung | 100% | 7391.61 | 578 / 578 | 100% | 94.78 | 1153 / 1155 |
| prostate | 100% | 7430.21 | 245 / 245 | 100% | 88.34 | 501 / 502 |
| ovary | 100% | 4684.33 | 180 / 180 | 100% | 75.92 | 429 / 430 |
| liver | 100% | 7902.82 | 226 / 226 | 100% | 64.24 | 405 / 406 |
| intestine | 100% | 6807.06 | 966 / 966 | 100% | 77.44 | 525 / 527 |
| skin | 100% | 8683.59 | 1809 / 1809 | 100% | 86.05 | 470 / 472 |
| esophagus | 100% | 6914.56 | 1445 / 1445 | 99% | 91.92 | 182 / 183 |
| stomach | 100% | 5684.88 | 359 / 359 | 99% | 76.82 | 284 / 286 |
| breast | 100% | 6681.88 | 459 / 459 | 99% | 62.03 | 1107 / 1118 |
| bladder | 100% | 7068.24 | 21 / 21 | 99% | 101.18 | 499 / 504 |
| thymus | 100% | 7074.92 | 653 / 653 | 99% | 54.87 | 596 / 605 |
| kidney | 100% | 5577.90 | 89 / 89 | 98% | 77.15 | 886 / 901 |
| uterus | 100% | 6501.95 | 170 / 170 | 98% | 79.16 | 451 / 459 |
| adrenal gland | 100% | 6715.64 | 258 / 258 | 97% | 41.34 | 222 / 230 |
| adipose | 100% | 6972.15 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 76.05 | 80 / 80 |
| spleen | 100% | 5061.86 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 68.52 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 54.04 | 1 / 1 |
| blood vessel | 100% | 4885.97 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 94% | 2358.50 | 813 / 861 | 0% | 0 | 0 / 0 |
| muscle | 78% | 1464.27 | 628 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 77% | 3407.54 | 715 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 55% | 10.80 | 16 / 29 |
| brain | 21% | 300.38 | 566 / 2642 | 25% | 5.63 | 175 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007165 | Biological process | signal transduction |
| GO_0006915 | Biological process | apoptotic process |
| GO_0006955 | Biological process | immune response |
| GO_2001238 | Biological process | positive regulation of extrinsic apoptotic signaling pathway |
| GO_0071260 | Biological process | cellular response to mechanical stimulus |
| GO_0043123 | Biological process | positive regulation of canonical NF-kappaB signal transduction |
| GO_0048534 | Biological process | hematopoietic or lymphoid organ development |
| GO_0043011 | Biological process | myeloid dendritic cell differentiation |
| GO_0046330 | Biological process | positive regulation of JNK cascade |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031625 | Molecular function | ubiquitin protein ligase binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0042802 | Molecular function | identical protein binding |
| Gene name | LTBR |
| Protein name | Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III) Lymphotoxin beta receptor |
| Synonyms | TNFRSF3 TNFR3 D12S370 TNFCR |
| Description | FUNCTION: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. . |
| Accessions | F5H627 ENST00000541102.1 ENST00000228918.9 [P36941-1] Q75UT6 ENST00000536876.5 F5H6F8 F5H2E7 P36941 F5H1S5 ENST00000539925.5 [P36941-2] ENST00000544454.5 ENST00000543190.5 |