SLC44A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006656Biological processphosphatidylcholine biosynthetic process
GO_0015871Biological processcholine transport
GO_0043123Biological processpositive regulation of canonical NF-kappaB signal transduction
GO_0055085Biological processtransmembrane transport
GO_0034229Biological processethanolamine transport
GO_0005741Cellular componentmitochondrial outer membrane
GO_0070062Cellular componentextracellular exosome
GO_0005765Cellular componentlysosomal membrane
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005739Cellular componentmitochondrion
GO_0034228Molecular functionethanolamine transmembrane transporter activity
GO_0015297Molecular functionantiporter activity
GO_0015220Molecular functioncholine transmembrane transporter activity
GO_0022857Molecular functiontransmembrane transporter activity

IV. Literature review

[source]
Gene nameSLC44A2
Protein nameCholine transporter-like protein
Choline transporter-like protein 2 (Solute carrier family 44 member 2)
Solute carrier family 44 member 2
SynonymshCG_28494
PSEC0210
CTL2
DescriptionFUNCTION: [Isoform 1]: Choline/H+ antiporter, mainly in mitochodria . Also acts as a low-affinity ethanolamine/H+ antiporter, regulating the supply of extracellular ethanolamine (Etn) for the CDP-Etn pathway, redistribute intracellular Etn and balance the CDP-Cho and CDP-Etn arms of the Kennedy pathway . .; FUNCTION: [Isoform 3]: Does not exhibit choline transporter activity. .

FUNCTION: Choline transporter. .

FUNCTION: Choline transporter. .

FUNCTION: Choline transporter. .

FUNCTION: Choline transporter. .

FUNCTION: Choline transporter. .

AccessionsK7EMR2
ENST00000335757.10 [Q8IWA5-1]
K7ESP7
K7ER17
ENST00000588688.5
Q8IWA5
A0A0S2YRM7
ENST00000590857.5
K7EPV6
ENST00000591194.5
ENST00000407327.8 [Q8IWA5-3]
ENST00000586078.5 [Q8IWA5-2]
ENST00000590382.5
K7EMN3
ENST00000586549.1
A0A024R798
ENST00000592293.5
A0A140TA83
A0A088QCU6
ENST00000588409.1
A0A088QF11
K7ESF5