SLC20A1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006811Biological processmonoatomic ion transport
GO_0035435Biological processphosphate ion transmembrane transport
GO_0006796Biological processphosphate-containing compound metabolic process
GO_0008283Biological processcell population proliferation
GO_0031214Biological processbiomineral tissue development
GO_0043123Biological processpositive regulation of canonical NF-kappaB signal transduction
GO_0035725Biological processsodium ion transmembrane transport
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005315Molecular functionphosphate transmembrane transporter activity
GO_0038023Molecular functionsignaling receptor activity
GO_0005316Molecular functionhigh-affinity phosphate:sodium symporter activity
GO_0005436Molecular functionsodium:phosphate symporter activity

IV. Literature review

[source]
Gene nameSLC20A1
Protein nameSodium-dependent phosphate transporter 1 (Solute carrier family 20 member 1)
Sodium-dependent phosphate transporter 1 (Gibbon ape leukemia virus receptor 1) (GLVR-1) (Leukemia virus receptor 1 homolog) (Phosphate transporter 1) (PiT-1) (Solute carrier family 20 member 1)
Phosphate transporter
SynonymsPIT1
GLVR1
hCG_15749
DescriptionFUNCTION: Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion . May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification . Essential for cell proliferation but this function is independent of its phosphate transporter activity . .; FUNCTION: (Microbial infection) May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV). .

FUNCTION: Sodium-phosphate symporter. .

AccessionsENST00000433924.5
H7BZY1
H7BZK4
A7LNJ1
Q8WUM9
ENST00000272542.8
ENST00000423633.5