MAS1 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of MAS1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
uterus	94%	70.48	159 / 170	0%	0.01	1 / 459
ovary	83%	27.01	149 / 180	1%	0.02	6 / 430
prostate	74%	34.97	182 / 245	1%	0.01	3 / 502
blood vessel	62%	27.46	825 / 1335	0%	0	0 / 0
brain	42%	202.02	1110 / 2642	10%	0.24	68 / 705
adipose	46%	14.93	549 / 1204	0%	0	0 / 0
stomach	28%	6.85	100 / 359	0%	0	0 / 286
thymus	26%	3.96	171 / 653	0%	0	0 / 605
breast	24%	4.23	109 / 459	0%	0.00	1 / 1118
heart	24%	3.35	203 / 861	0%	0	0 / 0
bladder	14%	2.00	3 / 21	0%	0	0 / 504
muscle	13%	1.85	108 / 803	0%	0	0 / 0
skin	11%	1.67	191 / 1809	2%	0.13	10 / 472
kidney	8%	1.08	7 / 89	0%	0.01	2 / 901
lung	7%	0.76	43 / 578	0%	0.00	1 / 1155
lymph node	0%	0	0 / 0	3%	0.05	1 / 29
spleen	3%	0.31	8 / 241	0%	0	0 / 0
peripheral blood	3%	0.40	29 / 929	0%	0	0 / 0
intestine	3%	0.39	30 / 966	0%	0	0 / 527
adrenal gland	3%	0.25	7 / 258	0%	0	0 / 230
esophagus	2%	0.37	30 / 1445	1%	0.01	1 / 183
liver	2%	0.14	4 / 226	0%	0	0 / 406
eye	0%	0	0 / 0	1%	0.54	1 / 80
pancreas	0%	0.04	1 / 328	1%	0.03	1 / 178
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007283	Biological process	spermatogenesis
GO_0021766	Biological process	hippocampus development
GO_0060732	Biological process	positive regulation of inositol phosphate biosynthetic process
GO_0050727	Biological process	regulation of inflammatory response
GO_0014823	Biological process	response to activity
GO_0001933	Biological process	negative regulation of protein phosphorylation
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0038166	Biological process	angiotensin-activated signaling pathway
GO_0043123	Biological process	positive regulation of canonical NF-kappaB signal transduction
GO_0045740	Biological process	positive regulation of DNA replication
GO_0008584	Biological process	male gonad development
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0070528	Biological process	protein kinase C signaling
GO_0009410	Biological process	response to xenobiotic stimulus
GO_0034698	Biological process	response to gonadotropin
GO_0005886	Cellular component	plasma membrane
GO_0009986	Cellular component	cell surface
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0042277	Molecular function	peptide binding
GO_0001595	Molecular function	angiotensin receptor activity
GO_0005515	Molecular function	protein binding
GO_0004945	Molecular function	angiotensin type II receptor activity

Gene name	MAS1
Protein name	Proto-oncogene Mas
Synonyms	MAS
Description	FUNCTION: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. .
Accessions	ENST00000252660.5 P04201 ENST00000674077.2

MAS1 report