Insufficient scRNA-seq data for expression of PRL at single-cell level.
Insufficient scRNA-seq data for expression of PRL at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 63% | 180.29 | 107 / 170 | 15% | 52.53 | 70 / 459 |
spleen | 66% | 210.00 | 160 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 59% | 513.83 | 151 / 258 | 6% | 0.24 | 13 / 230 |
ovary | 59% | 191.76 | 106 / 180 | 4% | 0.41 | 17 / 430 |
liver | 58% | 253.14 | 132 / 226 | 1% | 0.02 | 6 / 406 |
pancreas | 54% | 155.02 | 178 / 328 | 4% | 0.77 | 7 / 178 |
stomach | 52% | 1584.94 | 188 / 359 | 3% | 0.09 | 10 / 286 |
kidney | 54% | 111.13 | 48 / 89 | 0% | 0.00 | 1 / 901 |
thymus | 42% | 1085.22 | 273 / 653 | 8% | 0.40 | 51 / 605 |
peripheral blood | 50% | 117.99 | 462 / 929 | 0% | 0 | 0 / 0 |
prostate | 49% | 147.28 | 120 / 245 | 0% | 0 | 0 / 502 |
lung | 45% | 116.11 | 258 / 578 | 4% | 0.22 | 49 / 1155 |
esophagus | 42% | 287.12 | 614 / 1445 | 3% | 0.06 | 5 / 183 |
intestine | 43% | 118.99 | 411 / 966 | 2% | 0.09 | 13 / 527 |
skin | 37% | 294.35 | 667 / 1809 | 8% | 0.88 | 37 / 472 |
adipose | 41% | 134.72 | 496 / 1204 | 0% | 0 | 0 / 0 |
breast | 35% | 63.12 | 162 / 459 | 2% | 0.05 | 20 / 1118 |
brain | 36% | 137.86 | 944 / 2642 | 0% | 0.29 | 3 / 705 |
heart | 32% | 95.49 | 278 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 29% | 112.89 | 389 / 1335 | 0% | 0 | 0 / 0 |
muscle | 26% | 71.35 | 212 / 803 | 0% | 0 | 0 / 0 |
bladder | 14% | 12.38 | 3 / 21 | 3% | 0.79 | 15 / 504 |
eye | 0% | 0 | 0 / 0 | 6% | 0.24 | 5 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030879 | Biological process | mammary gland development |
GO_0007565 | Biological process | female pregnancy |
GO_0016525 | Biological process | negative regulation of angiogenesis |
GO_0031667 | Biological process | response to nutrient levels |
GO_0001937 | Biological process | negative regulation of endothelial cell proliferation |
GO_0043123 | Biological process | positive regulation of canonical NF-kappaB signal transduction |
GO_1902895 | Biological process | positive regulation of miRNA transcription |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0038161 | Biological process | prolactin signaling pathway |
GO_0007595 | Biological process | lactation |
GO_1903489 | Biological process | positive regulation of lactation |
GO_0046427 | Biological process | positive regulation of receptor signaling pathway via JAK-STAT |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0031904 | Cellular component | endosome lumen |
GO_0005179 | Molecular function | hormone activity |
GO_0005148 | Molecular function | prolactin receptor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | PRL |
Protein name | Prolactin Prolactin (PRL) |
Synonyms | GHA1 hCG_36753 |
Description | FUNCTION: Prolactin acts primarily on the mammary gland by promoting lactation. FUNCTION: Prolactin acts primarily on the mammary gland by promoting lactation. . FUNCTION: Prolactin acts primarily on the mammary gland by promoting lactation. . FUNCTION: Prolactin acts primarily on the mammary gland by promoting lactation. . FUNCTION: Prolactin acts primarily on the mammary gland by promoting lactation. . |
Accessions | Q5I0G2 A0A494C0Z0 Q5THQ0 P01236 ENST00000651245.1 ENST00000306482.2 ENST00000651757.1 ENST00000617911.4 A0A494C1P2 |