MIER1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	28 studies	23% ± 7%	Explore
endothelial cell	25 studies	27% ± 12%	Explore
CD4-positive, alpha-beta T cell	23 studies	21% ± 6%	Explore
CD8-positive, alpha-beta T cell	23 studies	22% ± 6%	Explore
fibroblast	21 studies	22% ± 7%	Explore
T cell	20 studies	22% ± 7%	Explore
mast cell	20 studies	26% ± 9%	Explore
pericyte	20 studies	21% ± 6%	Explore
regulatory T cell	18 studies	23% ± 4%	Explore
smooth muscle cell	17 studies	20% ± 4%	Explore
gamma-delta T cell	15 studies	25% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	23% ± 6%	Explore
classical monocyte	14 studies	23% ± 9%	Explore
B cell	13 studies	21% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	23% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	22% ± 5%	Explore
mature NK T cell	12 studies	23% ± 6%	Explore
mucosal invariant T cell	12 studies	24% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	25% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	26% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	23% ± 6%	Explore
non-classical monocyte	10 studies	26% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	24% ± 7%	Explore
endothelial cell of lymphatic vessel	9 studies	24% ± 5%	Explore
monocyte	9 studies	23% ± 5%	Explore
naive B cell	9 studies	19% ± 3%	Explore
memory B cell	9 studies	18% ± 2%	Explore
epithelial cell	9 studies	36% ± 18%	Explore
macrophage	8 studies	27% ± 7%	Explore
oligodendrocyte	8 studies	30% ± 10%	Explore
microglial cell	7 studies	26% ± 9%	Explore
myeloid cell	7 studies	26% ± 8%	Explore
astrocyte	7 studies	32% ± 13%	Explore
leukocyte	6 studies	26% ± 4%	Explore
capillary endothelial cell	6 studies	17% ± 1%	Explore
lymphocyte	6 studies	29% ± 12%	Explore
basal cell	6 studies	30% ± 15%	Explore
ciliated cell	6 studies	26% ± 12%	Explore
endothelial cell of artery	6 studies	18% ± 2%	Explore
T follicular helper cell	6 studies	22% ± 4%	Explore
endothelial cell of vascular tree	6 studies	23% ± 8%	Explore
type I pneumocyte	6 studies	19% ± 3%	Explore
oligodendrocyte precursor cell	6 studies	32% ± 11%	Explore
retinal rod cell	5 studies	19% ± 2%	Explore
dendritic cell	5 studies	31% ± 19%	Explore
Mueller cell	5 studies	23% ± 7%	Explore
myofibroblast cell	5 studies	18% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	27% ± 9%	Explore
innate lymphoid cell	5 studies	22% ± 3%	Explore
glutamatergic neuron	5 studies	48% ± 25%	Explore
goblet cell	5 studies	30% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	19% ± 3%	Explore
hematopoietic precursor cell	4 studies	33% ± 16%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	22% ± 4%	Explore
conventional dendritic cell	4 studies	28% ± 11%	Explore
neuron	4 studies	25% ± 13%	Explore
adipocyte	4 studies	20% ± 5%	Explore
vein endothelial cell	4 studies	22% ± 11%	Explore
abnormal cell	4 studies	25% ± 8%	Explore
GABAergic neuron	4 studies	46% ± 18%	Explore
connective tissue cell	4 studies	20% ± 3%	Explore
interneuron	4 studies	40% ± 23%	Explore
plasmacytoid dendritic cell	4 studies	21% ± 6%	Explore
neutrophil	3 studies	21% ± 4%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	26% ± 7%	Explore
exhausted T cell	3 studies	25% ± 10%	Explore
glomerular endothelial cell	3 studies	21% ± 1%	Explore
precursor B cell	3 studies	19% ± 2%	Explore
club cell	3 studies	25% ± 3%	Explore
retina horizontal cell	3 studies	20% ± 4%	Explore
retinal cone cell	3 studies	22% ± 4%	Explore
CD4-positive helper T cell	3 studies	28% ± 9%	Explore
muscle cell	3 studies	30% ± 11%	Explore
type II pneumocyte	3 studies	19% ± 3%	Explore
granulocyte	3 studies	27% ± 8%	Explore
enteroendocrine cell	3 studies	21% ± 2%	Explore
alveolar macrophage	3 studies	24% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	27% ± 9%	Explore
T-helper 17 cell	3 studies	22% ± 5%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	20% ± 3%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	17% ± 2%	Explore
double negative thymocyte	3 studies	30% ± 8%	Explore
mural cell	3 studies	28% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	23% ± 9%	Explore
brain	9 studies	36% ± 18%	Explore
lung	8 studies	24% ± 9%	Explore
eye	5 studies	25% ± 11%	Explore
bone marrow	4 studies	20% ± 3%	Explore
liver	4 studies	27% ± 8%	Explore
adipose	4 studies	20% ± 3%	Explore
uterus	3 studies	26% ± 7%	Explore
kidney	3 studies	17% ± 1%	Explore
intestine	3 studies	21% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2406.32	1445 / 1445	100%	25.51	183 / 183
lung	100%	2915.87	578 / 578	100%	19.61	1155 / 1155
ovary	100%	2964.39	180 / 180	100%	21.15	430 / 430
breast	100%	2713.29	459 / 459	100%	23.01	1117 / 1118
brain	100%	1505.83	2635 / 2642	100%	14.52	705 / 705
prostate	100%	2369.97	245 / 245	100%	16.85	500 / 502
thymus	100%	2297.20	653 / 653	100%	18.23	602 / 605
bladder	100%	2600.33	21 / 21	99%	16.34	501 / 504
uterus	100%	2988.06	170 / 170	99%	19.20	456 / 459
intestine	100%	3162.44	966 / 966	99%	17.75	521 / 527
stomach	100%	1883.09	359 / 359	99%	19.74	282 / 286
kidney	100%	1612.53	89 / 89	99%	18.20	888 / 901
adrenal gland	100%	2918.47	258 / 258	98%	11.17	226 / 230
pancreas	97%	972.16	319 / 328	98%	17.83	175 / 178
liver	100%	1611.60	226 / 226	95%	9.50	386 / 406
skin	100%	2452.02	1808 / 1809	90%	13.58	426 / 472
blood vessel	100%	3542.36	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	16.58	29 / 29
spleen	100%	2362.68	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	19.47	45 / 45
ureter	0%	0	0 / 0	100%	7.45	1 / 1
adipose	100%	2983.37	1203 / 1204	0%	0	0 / 0
muscle	99%	1062.35	793 / 803	0%	0	0 / 0
heart	98%	1193.02	848 / 861	0%	0	0 / 0
peripheral blood	96%	2659.26	888 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	63%	5.97	50 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0043123	Biological process	positive regulation of canonical NF-kappaB signal transduction
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0006338	Biological process	chromatin remodeling
GO_0006355	Biological process	regulation of DNA-templated transcription
GO_0032991	Cellular component	protein-containing complex
GO_0005654	Cellular component	nucleoplasm
GO_0017053	Cellular component	transcription repressor complex
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0004407	Molecular function	histone deacetylase activity
GO_0003714	Molecular function	transcription corepressor activity
GO_0005515	Molecular function	protein binding
GO_0042826	Molecular function	histone deacetylase binding

IV. Literature review

[source]

Gene name	MIER1
Protein name	Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (hMi-er1) MIER1 protein Alternative protein MIER1
Synonyms	KIAA1610
Description	FUNCTION: Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing. .
Accessions	ENST00000355977.10 [Q8N108-19] ENST00000371016.5 [Q8N108-14] ENST00000371018.7 [Q8N108-18] Q8N108 L8EC72 Q6NXT7 ENST00000371014.5 [Q8N108-15] ENST00000355356.3 [Q8N108-11] ENST00000401041.6 [Q8N108-12] ENST00000357692.6 [Q8N108-13] ENST00000401042.7 [Q8N108-16] ENST00000371012.6 [Q8N108-20]

MIER1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review