Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 5 studies | 23% ± 10% | |
| epithelial cell | 4 studies | 31% ± 10% | |
| plasmacytoid dendritic cell | 4 studies | 24% ± 8% | |
| monocyte | 3 studies | 21% ± 3% | |
| classical monocyte | 3 studies | 25% ± 6% | |
| conventional dendritic cell | 3 studies | 27% ± 12% | |
| hematopoietic precursor cell | 3 studies | 20% ± 3% | |
| myeloid cell | 3 studies | 27% ± 10% | |
| dendritic cell | 3 studies | 40% ± 12% | |
| erythroblast | 3 studies | 26% ± 9% |
Insufficient scRNA-seq data for expression of NUP62 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 3202.52 | 21 / 21 | 100% | 47.53 | 504 / 504 |
| esophagus | 100% | 3067.34 | 1445 / 1445 | 100% | 40.84 | 183 / 183 |
| ovary | 100% | 2935.76 | 180 / 180 | 100% | 45.39 | 430 / 430 |
| stomach | 100% | 2270.37 | 359 / 359 | 100% | 39.64 | 286 / 286 |
| uterus | 100% | 3634.30 | 170 / 170 | 100% | 62.19 | 459 / 459 |
| skin | 100% | 3662.96 | 1808 / 1809 | 100% | 52.51 | 472 / 472 |
| breast | 100% | 2947.71 | 459 / 459 | 100% | 47.78 | 1116 / 1118 |
| intestine | 100% | 3367.00 | 966 / 966 | 100% | 41.75 | 526 / 527 |
| prostate | 100% | 3161.84 | 245 / 245 | 100% | 32.58 | 501 / 502 |
| lung | 100% | 2885.77 | 577 / 578 | 100% | 42.87 | 1153 / 1155 |
| thymus | 100% | 2624.82 | 653 / 653 | 99% | 31.30 | 600 / 605 |
| brain | 99% | 2076.74 | 2619 / 2642 | 100% | 36.07 | 705 / 705 |
| pancreas | 100% | 1751.74 | 327 / 328 | 99% | 35.70 | 176 / 178 |
| kidney | 100% | 2532.48 | 89 / 89 | 98% | 27.21 | 887 / 901 |
| adrenal gland | 100% | 4121.29 | 258 / 258 | 98% | 27.28 | 226 / 230 |
| liver | 100% | 2443.39 | 226 / 226 | 96% | 21.60 | 390 / 406 |
| adipose | 100% | 2880.01 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2756.28 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 29.32 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 83.40 | 29 / 29 |
| muscle | 100% | 2785.09 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4273.09 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 69.25 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 24.65 | 1 / 1 |
| heart | 99% | 1731.51 | 853 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 4062.40 | 904 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009966 | Biological process | regulation of signal transduction |
| GO_0006405 | Biological process | RNA export from nucleus |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0046601 | Biological process | positive regulation of centriole replication |
| GO_0051028 | Biological process | mRNA transport |
| GO_0042059 | Biological process | negative regulation of epidermal growth factor receptor signaling pathway |
| GO_0046578 | Biological process | regulation of Ras protein signal transduction |
| GO_1903438 | Biological process | positive regulation of mitotic cytokinetic process |
| GO_0007100 | Biological process | mitotic centrosome separation |
| GO_0043069 | Biological process | negative regulation of programmed cell death |
| GO_0046580 | Biological process | negative regulation of Ras protein signal transduction |
| GO_0007098 | Biological process | centrosome cycle |
| GO_0045742 | Biological process | positive regulation of epidermal growth factor receptor signaling pathway |
| GO_1904781 | Biological process | positive regulation of protein localization to centrosome |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0043123 | Biological process | positive regulation of canonical NF-kappaB signal transduction |
| GO_0006606 | Biological process | protein import into nucleus |
| GO_0006913 | Biological process | nucleocytoplasmic transport |
| GO_0090398 | Biological process | cellular senescence |
| GO_0060236 | Biological process | regulation of mitotic spindle organization |
| GO_0098534 | Biological process | centriole assembly |
| GO_0007080 | Biological process | mitotic metaphase chromosome alignment |
| GO_0045840 | Biological process | positive regulation of mitotic nuclear division |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0044613 | Cellular component | nuclear pore central transport channel |
| GO_0005643 | Cellular component | nuclear pore |
| GO_0000922 | Cellular component | spindle pole |
| GO_0072686 | Cellular component | mitotic spindle |
| GO_0005813 | Cellular component | centrosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005635 | Cellular component | nuclear envelope |
| GO_0090543 | Cellular component | Flemming body |
| GO_0005737 | Cellular component | cytoplasm |
| GO_1990904 | Cellular component | ribonucleoprotein complex |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_0003682 | Molecular function | chromatin binding |
| GO_0005543 | Molecular function | phospholipid binding |
| GO_0051879 | Molecular function | Hsp90 protein binding |
| GO_0017056 | Molecular function | structural constituent of nuclear pore |
| GO_0042169 | Molecular function | SH2 domain binding |
| GO_0030159 | Molecular function | signaling receptor complex adaptor activity |
| GO_0030544 | Molecular function | Hsp70 protein binding |
| GO_0051425 | Molecular function | PTB domain binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0043130 | Molecular function | ubiquitin binding |
| Gene name | NUP62 |
| Protein name | Nuclear pore glycoprotein p62 Nucleoporin 62 Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62) |
| Synonyms | |
| Description | FUNCTION: Essential component of the nuclear pore complex . The N-terminal is probably involved in nucleocytoplasmic transport . The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex . Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation . It might be involved in protein recruitment to the centrosome after nuclear breakdown . . |
| Accessions | ENST00000700474.1 ENST00000599788.1 ENST00000595761.1 M0QXN5 M0QYY0 M0QZL5 ENST00000700478.1 M0R302 ENST00000700476.1 ENST00000600583.6 ENST00000352066.8 ENST00000600935.1 M0QX10 ENST00000597029.6 ENST00000700477.1 ENST00000600935.2 ENST00000598301.2 M0QX13 ENST00000596437.6 ENST00000599560.6 ENST00000593652.5 M0QX64 ENST00000700473.1 ENST00000422090.2 M0R1S1 ENST00000596437.5 ENST00000596217.1 ENST00000599567.5 P37198 ENST00000700475.1 ENST00000594673.5 ENST00000599788.2 ENST00000600645.1 ENST00000597723.5 |
