Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| microglial cell | 9 studies | 26% ± 7% | |
| macrophage | 8 studies | 45% ± 16% | |
| pericyte | 6 studies | 27% ± 8% | |
| oligodendrocyte | 6 studies | 25% ± 13% | |
| cardiac muscle cell | 5 studies | 36% ± 6% | |
| fibroblast | 5 studies | 26% ± 8% | |
| myeloid cell | 4 studies | 25% ± 5% | |
| astrocyte | 4 studies | 30% ± 21% | |
| glutamatergic neuron | 4 studies | 35% ± 12% | |
| endothelial cell | 3 studies | 38% ± 12% | |
| mesothelial cell | 3 studies | 27% ± 8% | |
| epithelial cell | 3 studies | 18% ± 1% | |
| oligodendrocyte precursor cell | 3 studies | 17% ± 2% | |
| smooth muscle cell | 3 studies | 23% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 1757.19 | 258 / 258 | 80% | 7.23 | 183 / 230 |
| prostate | 100% | 698.06 | 245 / 245 | 79% | 2.82 | 399 / 502 |
| kidney | 99% | 408.29 | 88 / 89 | 73% | 2.55 | 658 / 901 |
| thymus | 100% | 1047.86 | 653 / 653 | 72% | 4.07 | 433 / 605 |
| ovary | 100% | 900.60 | 180 / 180 | 69% | 2.00 | 298 / 430 |
| stomach | 100% | 583.06 | 359 / 359 | 48% | 1.97 | 136 / 286 |
| esophagus | 97% | 689.29 | 1404 / 1445 | 49% | 1.37 | 90 / 183 |
| lung | 99% | 677.32 | 574 / 578 | 45% | 1.17 | 518 / 1155 |
| intestine | 94% | 462.95 | 912 / 966 | 39% | 1.38 | 203 / 527 |
| uterus | 100% | 769.91 | 170 / 170 | 31% | 0.97 | 142 / 459 |
| bladder | 100% | 488.81 | 21 / 21 | 27% | 0.85 | 136 / 504 |
| pancreas | 100% | 447.23 | 328 / 328 | 24% | 0.45 | 42 / 178 |
| breast | 100% | 624.27 | 459 / 459 | 23% | 0.43 | 258 / 1118 |
| skin | 90% | 615.45 | 1627 / 1809 | 28% | 0.72 | 133 / 472 |
| brain | 68% | 143.18 | 1802 / 2642 | 39% | 0.63 | 273 / 705 |
| blood vessel | 100% | 622.57 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 811.34 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 99% | 265.76 | 238 / 241 | 0% | 0 | 0 / 0 |
| heart | 98% | 1089.50 | 847 / 861 | 0% | 0 | 0 / 0 |
| liver | 62% | 129.81 | 141 / 226 | 32% | 0.95 | 130 / 406 |
| muscle | 64% | 132.77 | 510 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 0.47 | 11 / 45 |
| eye | 0% | 0 | 0 / 0 | 13% | 0.19 | 10 / 80 |
| peripheral blood | 11% | 21.03 | 104 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0042475 | Biological process | odontogenesis of dentin-containing tooth |
| GO_0019221 | Biological process | cytokine-mediated signaling pathway |
| GO_0060789 | Biological process | hair follicle placode formation |
| GO_1901224 | Biological process | positive regulation of non-canonical NF-kappaB signal transduction |
| GO_0090263 | Biological process | positive regulation of canonical Wnt signaling pathway |
| GO_0007160 | Biological process | cell-matrix adhesion |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0060070 | Biological process | canonical Wnt signaling pathway |
| GO_0048513 | Biological process | animal organ development |
| GO_0006955 | Biological process | immune response |
| GO_0043123 | Biological process | positive regulation of canonical NF-kappaB signal transduction |
| GO_0030154 | Biological process | cell differentiation |
| GO_0043473 | Biological process | pigmentation |
| GO_0010467 | Biological process | gene expression |
| GO_0060662 | Biological process | salivary gland cavitation |
| GO_0061153 | Biological process | trachea gland development |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005811 | Cellular component | lipid droplet |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005581 | Cellular component | collagen trimer |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0045177 | Cellular component | apical part of cell |
| GO_0038177 | Molecular function | death receptor agonist activity |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0005123 | Molecular function | death receptor binding |
| GO_0005164 | Molecular function | tumor necrosis factor receptor binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005125 | Molecular function | cytokine activity |
| Gene name | EDA |
| Protein name | Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Cleaved into: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form] Mutant ectodysplasin A Ectodysplasin A Ectodysplasin A (HCG14664) |
| Synonyms | hCG_14664 EDA2 ED1 |
| Description | FUNCTION: Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R . May also play a role in cell adhesion (By similarity). .; FUNCTION: [Isoform 1]: Binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor EDA2R. .; FUNCTION: [Isoform 3]: Binds only to the receptor EDA2R. . |
| Accessions | ENST00000616899.1 ENST00000524573.5 [Q92838-9] ENST00000527388.5 [Q92838-7] A0A0K0KSD3 ENST00000338901.4 [Q92838-5] ENST00000525810.5 [Q92838-2] D6RA95 ENST00000503592.5 ENST00000374553.6 [Q92838-3] A0A0C4DGX3 ENST00000374552.9 [Q92838-1] Q92838 |