cytokine-mediated signaling pathway

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1CCL2-CCR2CCL2_HUMAN - CCR2_HUMANLigand-ReceptorSignaling by Chemokines
2CLCF1-CNTFR+IL6ST+LIFRCLCF1_HUMAN - Ligand-Receptor
3CRLF2-CRLF2+IL7RCRLF2_HUMAN - Receptor-Receptor
4CSF3-CSF3RCSF3_HUMAN - CSF3R_HUMANLigand-ReceptorSignaling by Colony-Stimulating factor
5EBI3+IL12A-IL12RB2+IL6ST - Ligand-ReceptorSignaling by Interleukin
6EBI3+IL27-IL27RA+IL6ST - Ligand-ReceptorSignaling by Interleukin
7GH1-GHRSOMA_HUMAN - GHR_HUMANLigand-ReceptorSignaling by Somatostatin
8IL12A+IL12B-IL12RB1+IL12RB2 - Ligand-ReceptorSignaling by Interleukin
9IL12B+IL23A-IL12RB1+IL23R - Ligand-ReceptorSignaling by Interleukin
10IL1A-IL1R2+IL1RAPIL1A_HUMAN - Ligand-ReceptorSignaling by Interleukin
11IL1B-IL1R2+IL1RAPIL1B_HUMAN - Ligand-ReceptorSignaling by Interleukin
12IL6-IL6R+IL6STIL6_HUMAN - Ligand-ReceptorSignaling by Interleukin
13IL7-IL2RG+IL7RIL7_HUMAN - Ligand-ReceptorSignaling by Interleukin

II. Literature review

[source]
Namecytokine-mediated signaling pathway
IDGO_0019221
collection_id

Biological process

Exact synonym

cytokine and chemokine mediated signaling pathway, cytokine mediated signalling pathway

Description

The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

External URL
Genes
GREM2NFKBIZKITEDA2RIFNA21IFNA17IL1BIFNA4IL22RA1IL6STIL1F10INHBACEBPAIL17RECSF1RIFNGR2LIFRIFNA6IRS1IL13RA1IFNKIL1ASH2B2IL2RGIL2RBCX3CL1EBI3DUOX1HCKIFNA5IL10RBIL11RAJAK3IL36GIFNA8CCR2IL13RA2JAK1CCR1IFNA2IRAK3LILRB4STAT3PLP2TYK2RELAPF4IL21RIL17RELLRP8IL31RARIPK2IFNB1SOCS5IFNLR1IFNA16IL27RASTAT4IL22RA2EDN2IL17RBGHRSTAT6il-10_il-10r_humanDUOX2IL7RSTAT5AIL20RAIRAK4CBLIL5RAAKT1IL4RCRLF1IL1R2CNOT9TNFRSF1AFZD4FOSL1CSF3RIL6RIFNGR1CSF2RAIFNW1BADCLCF1IFNA14FLT3PTPN11PRLRCSF3CTSGIL1RAPL2NUMBLOSMRLILRA4LEPRIL23RF3SOCS1IRF5IFNA10PTPRJIFNECRLF2IL20RBZC3H15IL12RB2EDAREREGIL17RDCCL2CD44JAK2EPORCSF2RBTNFSF11IL36BIL37STAT5BPTPN6IL36APIK3R1IL6IL12BIL12RB1CAV1IFNA1IL10RALILRA5PRKACAGH1FERIL3RASOS1SLC1A1IL7EDAIL9RIFNA7