Insufficient scRNA-seq data for expression of IFNK at single-cell level.
Insufficient scRNA-seq data for expression of IFNK at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 73% | 4.34 | 131 / 180 | 0% | 0.05 | 2 / 430 |
lung | 54% | 1.76 | 314 / 578 | 3% | 0.38 | 33 / 1155 |
spleen | 53% | 1.94 | 127 / 241 | 0% | 0 | 0 / 0 |
uterus | 42% | 1.28 | 71 / 170 | 9% | 1.93 | 40 / 459 |
peripheral blood | 41% | 1.60 | 378 / 929 | 0% | 0 | 0 / 0 |
intestine | 38% | 0.98 | 367 / 966 | 1% | 0.12 | 7 / 527 |
skin | 38% | 1.27 | 691 / 1809 | 0% | 0.00 | 1 / 472 |
breast | 35% | 1.01 | 159 / 459 | 2% | 0.15 | 19 / 1118 |
brain | 34% | 1.13 | 906 / 2642 | 0% | 0.01 | 2 / 705 |
adipose | 34% | 0.91 | 405 / 1204 | 0% | 0 | 0 / 0 |
thymus | 32% | 0.83 | 206 / 653 | 0% | 0.00 | 1 / 605 |
kidney | 29% | 0.91 | 26 / 89 | 1% | 0.13 | 10 / 901 |
esophagus | 26% | 0.63 | 373 / 1445 | 4% | 0.61 | 8 / 183 |
blood vessel | 28% | 0.72 | 371 / 1335 | 0% | 0 | 0 / 0 |
stomach | 25% | 0.61 | 88 / 359 | 3% | 0.22 | 8 / 286 |
pancreas | 25% | 0.55 | 82 / 328 | 2% | 0.04 | 3 / 178 |
prostate | 25% | 0.53 | 62 / 245 | 1% | 0.11 | 4 / 502 |
adrenal gland | 24% | 0.56 | 63 / 258 | 0% | 0 | 0 / 230 |
muscle | 23% | 0.53 | 181 / 803 | 0% | 0 | 0 / 0 |
heart | 20% | 0.42 | 175 / 861 | 0% | 0 | 0 / 0 |
bladder | 14% | 0.29 | 3 / 21 | 6% | 0.79 | 29 / 504 |
tonsil | 0% | 0 | 0 / 0 | 11% | 0.31 | 5 / 45 |
liver | 10% | 0.66 | 23 / 226 | 0% | 0 | 0 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0019221 | Biological process | cytokine-mediated signaling pathway |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0033141 | Biological process | positive regulation of peptidyl-serine phosphorylation of STAT protein |
GO_0043330 | Biological process | response to exogenous dsRNA |
GO_0009615 | Biological process | response to virus |
GO_0051607 | Biological process | defense response to virus |
GO_0030101 | Biological process | natural killer cell activation |
GO_0045089 | Biological process | positive regulation of innate immune response |
GO_0006959 | Biological process | humoral immune response |
GO_0002250 | Biological process | adaptive immune response |
GO_0098586 | Biological process | cellular response to virus |
GO_0060337 | Biological process | type I interferon-mediated signaling pathway |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0042100 | Biological process | B cell proliferation |
GO_0002323 | Biological process | natural killer cell activation involved in immune response |
GO_0030183 | Biological process | B cell differentiation |
GO_0002286 | Biological process | T cell activation involved in immune response |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005132 | Molecular function | type I interferon receptor binding |
GO_0005125 | Molecular function | cytokine activity |
Gene name | IFNK |
Protein name | Interferon kappa (IFN-kappa) Interferon 1FA (Interferon, kappa) |
Synonyms | UNQ6124/PRO20084 hCG_1658903 IF1FA |
Description | FUNCTION: May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin. . |
Accessions | A0A7R8GUT1 Q9P0W0 ENST00000276943.3 |