B cell differentiation

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1CD40LG-ITGA5+ITGB1CD40L_HUMAN - Ligand-Receptor
2VCAM1-ITGA4+ITGB1VCAM1_HUMAN - Ligand-ReceptorAdhesion by VCAM
3VCAM1-ITGA4+ITGB7VCAM1_HUMAN - Ligand-ReceptorAdhesion by VCAM
4VCAM1-ITGA9+ITGB1VCAM1_HUMAN - Ligand-ReceptorAdhesion by VCAM

II. Literature review

[source]
NameB cell differentiation
IDGO_0030183
collection_id

Biological process

Alternative ID

GO:0042115

Exact synonym

B lymphocyte differentiation, B-cell differentiation, B-lymphocyte differentiation

Description

The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.

Related synonym

B cell development

Comment

Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

External URL
Genes