Insufficient scRNA-seq data for expression of IFNE at single-cell level.
Insufficient scRNA-seq data for expression of IFNE at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 83% | 24.02 | 544 / 653 | 53% | 2.66 | 320 / 605 |
| bladder | 67% | 69.90 | 14 / 21 | 38% | 2.23 | 192 / 504 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.80 | 1 / 1 |
| esophagus | 36% | 33.46 | 527 / 1445 | 56% | 2.34 | 102 / 183 |
| stomach | 72% | 31.41 | 258 / 359 | 11% | 0.25 | 31 / 286 |
| prostate | 78% | 43.55 | 190 / 245 | 1% | 0.02 | 6 / 502 |
| kidney | 54% | 18.55 | 48 / 89 | 23% | 0.88 | 211 / 901 |
| uterus | 15% | 6.52 | 26 / 170 | 61% | 3.38 | 279 / 459 |
| pancreas | 3% | 0.39 | 9 / 328 | 53% | 3.56 | 95 / 178 |
| skin | 34% | 44.01 | 619 / 1809 | 4% | 0.13 | 19 / 472 |
| brain | 32% | 13.90 | 849 / 2642 | 1% | 0.02 | 8 / 705 |
| lung | 10% | 1.62 | 55 / 578 | 21% | 0.75 | 242 / 1155 |
| intestine | 17% | 6.93 | 169 / 966 | 11% | 0.44 | 59 / 527 |
| tonsil | 0% | 0 | 0 / 0 | 27% | 1.38 | 12 / 45 |
| breast | 21% | 4.73 | 95 / 459 | 3% | 0.06 | 33 / 1118 |
| ovary | 3% | 0.57 | 6 / 180 | 9% | 0.19 | 40 / 430 |
| adipose | 10% | 1.92 | 122 / 1204 | 0% | 0 | 0 / 0 |
| heart | 3% | 0.56 | 22 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 1% | 0.13 | 2 / 258 | 2% | 0.14 | 4 / 230 |
| blood vessel | 2% | 0.23 | 21 / 1335 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 1% | 0.06 | 5 / 406 |
| peripheral blood | 1% | 0.12 | 9 / 929 | 0% | 0 | 0 / 0 |
| spleen | 1% | 0.11 | 2 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0043330 | Biological process | response to exogenous dsRNA |
| GO_0002250 | Biological process | adaptive immune response |
| GO_0019221 | Biological process | cytokine-mediated signaling pathway |
| GO_0098586 | Biological process | cellular response to virus |
| GO_0042100 | Biological process | B cell proliferation |
| GO_0060337 | Biological process | type I interferon-mediated signaling pathway |
| GO_0051607 | Biological process | defense response to virus |
| GO_0033141 | Biological process | positive regulation of peptidyl-serine phosphorylation of STAT protein |
| GO_0002323 | Biological process | natural killer cell activation involved in immune response |
| GO_0030183 | Biological process | B cell differentiation |
| GO_0002286 | Biological process | T cell activation involved in immune response |
| GO_0042742 | Biological process | defense response to bacterium |
| GO_0006959 | Biological process | humoral immune response |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005132 | Molecular function | type I interferon receptor binding |
| GO_0005125 | Molecular function | cytokine activity |
| Gene name | IFNE |
| Protein name | Interferon epsilon (IFN-epsilon) (Interferon epsilon-1) |
| Synonyms | IFNE1 UNQ360/PRO655 |
| Description | FUNCTION: Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and bacterial genital infections (By similarity). . |
| Accessions | ENST00000448696.4 Q86WN2 |