Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 50 studies | 74% ± 21% | |
memory B cell | 21 studies | 87% ± 16% | |
naive B cell | 20 studies | 88% ± 8% | |
immature B cell | 7 studies | 85% ± 16% | |
precursor B cell | 5 studies | 47% ± 26% | |
germinal center B cell | 4 studies | 76% ± 20% | |
plasmablast | 3 studies | 28% ± 10% | |
follicular B cell | 3 studies | 75% ± 11% | |
plasma cell | 3 studies | 51% ± 22% | |
erythrocyte | 3 studies | 31% ± 18% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lymph node | 3 studies | 38% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 92% | 544.34 | 533 / 578 | 59% | 9.46 | 681 / 1155 |
lymph node | 0% | 0 | 0 / 0 | 100% | 626.00 | 29 / 29 |
spleen | 100% | 32887.61 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 15777.83 | 920 / 929 | 0% | 0 | 0 / 0 |
stomach | 41% | 247.70 | 148 / 359 | 37% | 8.18 | 105 / 286 |
thymus | 42% | 1040.73 | 276 / 653 | 35% | 8.15 | 213 / 605 |
intestine | 48% | 4186.48 | 459 / 966 | 26% | 8.46 | 137 / 527 |
breast | 30% | 90.60 | 136 / 459 | 40% | 7.65 | 452 / 1118 |
kidney | 55% | 506.01 | 49 / 89 | 14% | 0.92 | 126 / 901 |
liver | 54% | 120.04 | 123 / 226 | 10% | 2.53 | 40 / 406 |
bladder | 38% | 200.57 | 8 / 21 | 24% | 9.00 | 119 / 504 |
tonsil | 0% | 0 | 0 / 0 | 60% | 19.08 | 27 / 45 |
prostate | 35% | 274.84 | 86 / 245 | 19% | 1.80 | 94 / 502 |
esophagus | 26% | 213.92 | 377 / 1445 | 25% | 4.87 | 46 / 183 |
pancreas | 4% | 4.56 | 12 / 328 | 42% | 14.47 | 74 / 178 |
adipose | 38% | 205.95 | 452 / 1204 | 0% | 0 | 0 / 0 |
skin | 2% | 4.01 | 41 / 1809 | 35% | 13.74 | 166 / 472 |
uterus | 11% | 11.89 | 18 / 170 | 22% | 1.85 | 100 / 459 |
blood vessel | 12% | 220.85 | 163 / 1335 | 0% | 0 | 0 / 0 |
heart | 10% | 40.12 | 86 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 7% | 12.15 | 17 / 258 | 3% | 0.08 | 6 / 230 |
ovary | 4% | 10.76 | 7 / 180 | 5% | 0.25 | 21 / 430 |
eye | 0% | 0 | 0 / 0 | 4% | 0.49 | 3 / 80 |
brain | 1% | 1.85 | 33 / 2642 | 1% | 1.32 | 8 / 705 |
muscle | 1% | 1.58 | 6 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0002115 | Biological process | store-operated calcium entry |
GO_0009617 | Biological process | response to bacterium |
GO_0050853 | Biological process | B cell receptor signaling pathway |
GO_1902656 | Biological process | calcium ion import into cytosol |
GO_0006959 | Biological process | humoral immune response |
GO_0051262 | Biological process | protein tetramerization |
GO_0042113 | Biological process | B cell activation |
GO_1905665 | Biological process | positive regulation of calcium ion import across plasma membrane |
GO_0042100 | Biological process | B cell proliferation |
GO_0030183 | Biological process | B cell differentiation |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0005615 | Cellular component | extracellular space |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0009986 | Cellular component | cell surface |
GO_0044853 | Cellular component | plasma membrane raft |
GO_0005154 | Molecular function | epidermal growth factor receptor binding |
GO_0019865 | Molecular function | immunoglobulin binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0023026 | Molecular function | MHC class II protein complex binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MS4A1 |
Protein name | Membrane spanning 4-domains A1 B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1) (Bp35) (Leukocyte surface antigen Leu-16) (Membrane-spanning 4-domains subfamily A member 1) (CD antigen CD20) |
Synonyms | CD20 |
Description | FUNCTION: B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes . Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR . . |
Accessions | ENST00000674194.1 [P11836-1] E9PPL6 ENST00000389939.2 [P11836-1] E9PKH8 ENST00000528313.1 [P11836-2] P11836 ENST00000533306.6 ENST00000532073.5 ENST00000345732.9 [P11836-1] ENST00000534668.6 [P11836-1] |