| Name | store-operated calcium entry |
| ID | GO_0002115 |
| collection_id | Biological process |
| Exact synonym | SOCE, capacitative calcium entry, store-operated calcium import |
| Description | A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum. |
| Comment | SOCE is initiated by response to stiumlation of membrane receptors leading to the hydrolysis ofphosphatidylinositol bisphosphate (PIP2), inositol 1,4,5-trisphosphate (IP3) generation, and IP3-mediated calcium ion release from the endoplasmic reticulum. |
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