Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 7 studies | 23% ± 8% | |
| non-classical monocyte | 4 studies | 25% ± 6% | |
| plasmacytoid dendritic cell | 4 studies | 20% ± 3% | |
| hematopoietic precursor cell | 3 studies | 23% ± 7% | |
| conventional dendritic cell | 3 studies | 33% ± 13% | |
| myeloid cell | 3 studies | 20% ± 3% | |
| epithelial cell | 3 studies | 27% ± 7% | |
| ciliated cell | 3 studies | 25% ± 5% |
Insufficient scRNA-seq data for expression of ORAI3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 2681.14 | 245 / 245 | 100% | 26.30 | 502 / 502 |
| thymus | 100% | 1750.92 | 653 / 653 | 100% | 25.35 | 604 / 605 |
| skin | 100% | 1540.08 | 1808 / 1809 | 100% | 15.34 | 470 / 472 |
| liver | 100% | 3307.75 | 226 / 226 | 100% | 18.47 | 404 / 406 |
| kidney | 100% | 1581.88 | 89 / 89 | 99% | 26.58 | 895 / 901 |
| adrenal gland | 100% | 3038.21 | 258 / 258 | 99% | 27.24 | 228 / 230 |
| ovary | 100% | 1861.42 | 180 / 180 | 99% | 14.65 | 426 / 430 |
| breast | 100% | 1587.11 | 459 / 459 | 97% | 16.30 | 1088 / 1118 |
| pancreas | 100% | 926.73 | 328 / 328 | 97% | 13.79 | 173 / 178 |
| intestine | 100% | 1872.60 | 966 / 966 | 96% | 10.24 | 507 / 527 |
| lung | 100% | 1453.57 | 576 / 578 | 97% | 11.69 | 1115 / 1155 |
| uterus | 100% | 2045.07 | 170 / 170 | 95% | 14.27 | 438 / 459 |
| brain | 97% | 640.87 | 2569 / 2642 | 97% | 9.52 | 685 / 705 |
| bladder | 100% | 2695.38 | 21 / 21 | 94% | 14.02 | 473 / 504 |
| stomach | 99% | 1294.91 | 357 / 359 | 91% | 8.84 | 261 / 286 |
| esophagus | 100% | 1910.37 | 1445 / 1445 | 85% | 8.84 | 155 / 183 |
| adipose | 100% | 1661.98 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 21.51 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 20.89 | 29 / 29 |
| spleen | 100% | 2141.68 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 14.41 | 1 / 1 |
| blood vessel | 100% | 1474.85 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 934.13 | 850 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 1885.26 | 908 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 9.99 | 42 / 45 |
| muscle | 81% | 429.17 | 652 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0070588 | Biological process | calcium ion transmembrane transport |
| GO_0002115 | Biological process | store-operated calcium entry |
| GO_0016020 | Cellular component | membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005515 | Molecular function | protein binding |
| GO_0015279 | Molecular function | store-operated calcium channel activity |
| Gene name | ORAI3 |
| Protein name | ORAI calcium release-activated calcium modulator 3 Protein orai-3 (Transmembrane protein 142C) |
| Synonyms | TMEM142C |
| Description | FUNCTION: Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1. . |
| Accessions | ENST00000566237.1 ENST00000562699.1 H3BTY7 H3BTK7 Q9BRQ5 ENST00000318663.5 H3BT51 ENST00000563161.1 |