Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 15 studies | 28% ± 10% | |
macrophage | 10 studies | 29% ± 9% | |
adipocyte | 10 studies | 30% ± 6% | |
fibroblast | 10 studies | 27% ± 12% | |
astrocyte | 10 studies | 36% ± 16% | |
natural killer cell | 9 studies | 27% ± 12% | |
CD16-positive, CD56-dim natural killer cell, human | 9 studies | 21% ± 9% | |
microglial cell | 9 studies | 26% ± 7% | |
mast cell | 9 studies | 29% ± 10% | |
glutamatergic neuron | 8 studies | 40% ± 25% | |
oligodendrocyte precursor cell | 8 studies | 28% ± 13% | |
B cell | 6 studies | 29% ± 7% | |
T cell | 6 studies | 33% ± 7% | |
GABAergic neuron | 6 studies | 44% ± 21% | |
epithelial cell | 5 studies | 36% ± 20% | |
CD16-negative, CD56-bright natural killer cell, human | 5 studies | 26% ± 9% | |
CD4-positive, alpha-beta T cell | 5 studies | 26% ± 10% | |
CD8-positive, alpha-beta T cell | 5 studies | 25% ± 9% | |
dendritic cell | 5 studies | 24% ± 4% | |
ciliated cell | 5 studies | 22% ± 4% | |
myeloid cell | 5 studies | 27% ± 6% | |
monocyte | 5 studies | 37% ± 9% | |
pericyte | 5 studies | 25% ± 7% | |
smooth muscle cell | 5 studies | 23% ± 5% | |
lymphocyte | 4 studies | 43% ± 19% | |
endothelial cell of lymphatic vessel | 4 studies | 22% ± 1% | |
type I pneumocyte | 4 studies | 20% ± 4% | |
basal cell | 4 studies | 33% ± 21% | |
interneuron | 4 studies | 45% ± 24% | |
neuron | 3 studies | 24% ± 7% | |
GABAergic interneuron | 3 studies | 21% ± 2% | |
plasma cell | 3 studies | 23% ± 6% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 27% ± 8% | |
endothelial cell of vascular tree | 3 studies | 26% ± 13% | |
hepatocyte | 3 studies | 52% ± 25% | |
ependymal cell | 3 studies | 32% ± 13% | |
alveolar macrophage | 3 studies | 45% ± 13% | |
type II pneumocyte | 3 studies | 18% ± 2% | |
leukocyte | 3 studies | 40% ± 12% | |
CD8-positive, alpha-beta memory T cell | 3 studies | 21% ± 3% | |
regulatory T cell | 3 studies | 21% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 8843.31 | 1445 / 1445 | 100% | 38.60 | 183 / 183 |
thymus | 100% | 7009.76 | 653 / 653 | 100% | 68.81 | 604 / 605 |
prostate | 100% | 4993.97 | 245 / 245 | 100% | 42.74 | 501 / 502 |
liver | 100% | 3867.38 | 226 / 226 | 100% | 36.86 | 404 / 406 |
lung | 100% | 5062.17 | 578 / 578 | 99% | 37.16 | 1149 / 1155 |
breast | 100% | 6143.07 | 459 / 459 | 99% | 41.39 | 1111 / 1118 |
stomach | 100% | 4609.70 | 359 / 359 | 99% | 24.20 | 284 / 286 |
skin | 100% | 6819.02 | 1809 / 1809 | 99% | 32.66 | 468 / 472 |
uterus | 100% | 6798.26 | 170 / 170 | 99% | 29.21 | 455 / 459 |
intestine | 100% | 5662.32 | 966 / 966 | 99% | 24.46 | 522 / 527 |
kidney | 100% | 3335.69 | 89 / 89 | 99% | 37.35 | 891 / 901 |
bladder | 100% | 5532.90 | 21 / 21 | 98% | 26.43 | 493 / 504 |
brain | 96% | 4312.19 | 2544 / 2642 | 100% | 38.31 | 704 / 705 |
pancreas | 96% | 2225.66 | 316 / 328 | 99% | 31.31 | 177 / 178 |
ovary | 100% | 7074.77 | 180 / 180 | 95% | 22.81 | 410 / 430 |
adrenal gland | 100% | 3259.03 | 257 / 258 | 94% | 30.95 | 216 / 230 |
adipose | 100% | 6620.48 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 6967.09 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 30.41 | 29 / 29 |
muscle | 100% | 12570.62 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 5949.93 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 38.75 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 17.73 | 1 / 1 |
eye | 0% | 0 | 0 / 0 | 99% | 31.04 | 79 / 80 |
peripheral blood | 98% | 5300.17 | 910 / 929 | 0% | 0 | 0 / 0 |
heart | 92% | 1969.49 | 793 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032237 | Biological process | activation of store-operated calcium channel activity |
GO_0045762 | Biological process | positive regulation of adenylate cyclase activity |
GO_0051924 | Biological process | regulation of calcium ion transport |
GO_0045766 | Biological process | positive regulation of angiogenesis |
GO_0002115 | Biological process | store-operated calcium entry |
GO_0006874 | Biological process | intracellular calcium ion homeostasis |
GO_0070166 | Biological process | enamel mineralization |
GO_2001256 | Biological process | regulation of store-operated calcium entry |
GO_0005513 | Biological process | detection of calcium ion |
GO_0032541 | Cellular component | cortical endoplasmic reticulum |
GO_0005886 | Cellular component | plasma membrane |
GO_0005874 | Cellular component | microtubule |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0044853 | Cellular component | plasma membrane raft |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0033017 | Cellular component | sarcoplasmic reticulum membrane |
GO_0051010 | Molecular function | microtubule plus-end binding |
GO_0005246 | Molecular function | calcium channel regulator activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0002020 | Molecular function | protease binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | STIM1 |
Protein name | STIM1 STIM1L (Stromal interaction molecule 1) Stromal interaction molecule 1 |
Synonyms | GOK |
Description | FUNCTION: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores . Acts as a Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 . Involved in enamel formation . Activated following interaction with STIMATE, leading to promote STIM1 conformational switch . . |
Accessions | ENST00000698911.1 E9PIQ8 E9PJ19 A0A8V8TMG5 ENST00000698918.1 ENST00000698912.1 E9PRZ7 E9PMB4 E9PN27 V5J3L2 ENST00000525055.5 ENST00000524822.5 A0A8V8TNW5 ENST00000532610.5 ENST00000698910.1 ENST00000527651.5 [Q13586-2] ENST00000698913.1 ENST00000526596.2 ENST00000530554.5 A0A8V8TP78 E9PNJ4 ENST00000698915.1 G0XQ39 A0A8V8TP73 ENST00000533977.5 E9PR09 ENST00000532990.1 ENST00000698916.1 A0A8V8TNW0 ENST00000532919.5 E9PR07 Q13586 E9PRE4 ENST00000300737.8 [Q13586-1] ENST00000698919.1 ENST00000616714.4 A0A8V8TMG1 ENST00000528656.5 H0YDB2 A0A8V8TMX0 A0A8V8TMF0 ENST00000525403.6 ENST00000698914.1 |