STIM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032237Biological processactivation of store-operated calcium channel activity
GO_0045762Biological processpositive regulation of adenylate cyclase activity
GO_0051924Biological processregulation of calcium ion transport
GO_0045766Biological processpositive regulation of angiogenesis
GO_0002115Biological processstore-operated calcium entry
GO_0006874Biological processintracellular calcium ion homeostasis
GO_0070166Biological processenamel mineralization
GO_2001256Biological processregulation of store-operated calcium entry
GO_0005513Biological processdetection of calcium ion
GO_0032541Cellular componentcortical endoplasmic reticulum
GO_0005886Cellular componentplasma membrane
GO_0005874Cellular componentmicrotubule
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0044853Cellular componentplasma membrane raft
GO_0005783Cellular componentendoplasmic reticulum
GO_0033017Cellular componentsarcoplasmic reticulum membrane
GO_0051010Molecular functionmicrotubule plus-end binding
GO_0005246Molecular functioncalcium channel regulator activity
GO_0042802Molecular functionidentical protein binding
GO_0002020Molecular functionprotease binding
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSTIM1
Protein nameSTIM1
STIM1L (Stromal interaction molecule 1)
Stromal interaction molecule 1
SynonymsGOK
DescriptionFUNCTION: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores . Acts as a Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 . Involved in enamel formation . Activated following interaction with STIMATE, leading to promote STIM1 conformational switch . .

AccessionsENST00000698911.1
E9PIQ8
E9PJ19
A0A8V8TMG5
ENST00000698918.1
ENST00000698912.1
E9PRZ7
E9PMB4
E9PN27
V5J3L2
ENST00000525055.5
ENST00000524822.5
A0A8V8TNW5
ENST00000532610.5
ENST00000698910.1
ENST00000527651.5 [Q13586-2]
ENST00000698913.1
ENST00000526596.2
ENST00000530554.5
A0A8V8TP78
E9PNJ4
ENST00000698915.1
G0XQ39
A0A8V8TP73
ENST00000533977.5
E9PR09
ENST00000532990.1
ENST00000698916.1
A0A8V8TNW0
ENST00000532919.5
E9PR07
Q13586
E9PRE4
ENST00000300737.8 [Q13586-1]
ENST00000698919.1
ENST00000616714.4
A0A8V8TMG1
ENST00000528656.5
H0YDB2
A0A8V8TMX0
A0A8V8TMF0
ENST00000525403.6
ENST00000698914.1