Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 2730.08 | 578 / 578 | 100% | 17.29 | 1155 / 1155 |
brain | 100% | 1680.90 | 2639 / 2642 | 100% | 19.88 | 705 / 705 |
intestine | 100% | 1820.12 | 966 / 966 | 100% | 13.23 | 526 / 527 |
bladder | 100% | 2043.05 | 21 / 21 | 100% | 12.94 | 503 / 504 |
prostate | 100% | 2371.71 | 245 / 245 | 100% | 16.84 | 501 / 502 |
thymus | 100% | 2134.33 | 653 / 653 | 100% | 13.68 | 602 / 605 |
pancreas | 100% | 1178.58 | 328 / 328 | 99% | 14.35 | 177 / 178 |
esophagus | 100% | 1138.21 | 1444 / 1445 | 99% | 15.45 | 182 / 183 |
breast | 100% | 2450.39 | 459 / 459 | 99% | 12.29 | 1111 / 1118 |
stomach | 100% | 1339.54 | 359 / 359 | 99% | 12.58 | 284 / 286 |
uterus | 100% | 2104.87 | 170 / 170 | 99% | 14.96 | 455 / 459 |
ovary | 100% | 3129.79 | 180 / 180 | 97% | 8.14 | 419 / 430 |
kidney | 100% | 2211.53 | 89 / 89 | 96% | 10.63 | 864 / 901 |
adrenal gland | 100% | 1389.33 | 258 / 258 | 96% | 8.78 | 220 / 230 |
skin | 100% | 2171.10 | 1809 / 1809 | 94% | 18.74 | 446 / 472 |
liver | 100% | 956.37 | 225 / 226 | 89% | 6.10 | 361 / 406 |
adipose | 100% | 2142.13 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 24.31 | 29 / 29 |
spleen | 100% | 3676.71 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 18.55 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.16 | 1 / 1 |
blood vessel | 100% | 1230.27 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 870.67 | 853 / 861 | 0% | 0 | 0 / 0 |
muscle | 97% | 705.83 | 775 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 94% | 1133.77 | 869 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 63% | 5.00 | 50 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032237 | Biological process | activation of store-operated calcium channel activity |
GO_0006874 | Biological process | intracellular calcium ion homeostasis |
GO_0070588 | Biological process | calcium ion transmembrane transport |
GO_0002115 | Biological process | store-operated calcium entry |
GO_0051928 | Biological process | positive regulation of calcium ion transport |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005886 | Cellular component | plasma membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005246 | Molecular function | calcium channel regulator activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0015279 | Molecular function | store-operated calcium channel activity |
Gene name | STIM2 |
Protein name | STIM2 protein Stromal interaction molecule 2 |
Synonyms | KIAA1482 |
Description | FUNCTION: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx. . |
Accessions | H7C5C6 H0Y860 ENST00000477474.3 A0A1X7SBY3 ENST00000698882.1 ENST00000467087.7 [Q9P246-1] ENST00000463501.5 ENST00000494628.6 ENST00000467087 ENST00000467011 H7C5A5 ENST00000467011.6 [Q9P246-3] H7C5K2 ENST00000478049.1 R4GN82 A0A8V8TMC8 ENST00000473519.5 Q05BJ5 R4GMP0 R4GNC5 ENST00000465503.6 Q9P246 |