ADGRG3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADGRG3 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0030334Biological processregulation of cell migration
GO_0030183Biological processB cell differentiation
GO_0032792Biological processnegative regulation of CREB transcription factor activity
GO_0007166Biological processcell surface receptor signaling pathway
GO_1901223Biological processnegative regulation of non-canonical NF-kappaB signal transduction
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameADGRG3
Protein nameAdhesion G protein-coupled receptor G3
Adhesion G protein-coupled receptor G3 (G-protein coupled receptor 97) (G-protein coupled receptor PGR26)
SynonymsGPR97
PGR26
DescriptionFUNCTION: Orphan receptor that regulates migration of lymphatic endothelial cells in vitro via the small GTPases RhoA and CDC42 . Regulates B-cell development (By similarity). Seems to signal through G-alpha(q)-proteins . .

AccessionsENST00000333493.9
ENST00000567991.5
ENST00000568245.5
ENST00000450388.7
Q86Y34
H3BS78
F8W8F7
H3BRU4