IFNA2 | OmnibusX

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of IFNA2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	69%	4.65	1821 / 2642	0%	0	0 / 705
spleen	69%	5.61	166 / 241	0%	0	0 / 0
peripheral blood	21%	41.38	191 / 929	0%	0	0 / 0
ovary	17%	1.06	30 / 180	0%	0	0 / 430
breast	16%	0.71	72 / 459	0%	0.00	2 / 1118
adipose	13%	0.55	158 / 1204	0%	0	0 / 0
bladder	10%	0.19	2 / 21	0%	0	0 / 504
intestine	8%	0.25	79 / 966	0%	0	0 / 527
esophagus	8%	0.21	117 / 1445	0%	0	0 / 183
blood vessel	7%	0.15	87 / 1335	0%	0	0 / 0
skin	6%	0.19	112 / 1809	0%	0	0 / 472
lung	6%	0.13	35 / 578	0%	0	0 / 1155
uterus	5%	0.15	9 / 170	0%	0	0 / 459
stomach	4%	0.10	16 / 359	0%	0.00	1 / 286
pancreas	5%	0.15	15 / 328	0%	0	0 / 178
prostate	4%	0.09	9 / 245	0%	0	0 / 502
kidney	3%	0.09	3 / 89	0%	0.00	1 / 901
muscle	3%	0.08	25 / 803	0%	0	0 / 0
adrenal gland	3%	0.06	7 / 258	0%	0	0 / 230
liver	3%	0.09	6 / 226	0%	0	0 / 406
thymus	3%	0.06	17 / 653	0%	0	0 / 605
heart	2%	0.06	16 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0019221	Biological process	cytokine-mediated signaling pathway
GO_0033141	Biological process	positive regulation of peptidyl-serine phosphorylation of STAT protein
GO_0006954	Biological process	inflammatory response
GO_0097696	Biological process	cell surface receptor signaling pathway via STAT
GO_0045581	Biological process	negative regulation of T cell differentiation
GO_0010629	Biological process	negative regulation of gene expression
GO_0043330	Biological process	response to exogenous dsRNA
GO_0051607	Biological process	defense response to virus
GO_0046597	Biological process	negative regulation of viral entry into host cell
GO_0007267	Biological process	cell-cell signaling
GO_0006959	Biological process	humoral immune response
GO_2000552	Biological process	negative regulation of T-helper 2 cell cytokine production
GO_0002250	Biological process	adaptive immune response
GO_0098586	Biological process	cellular response to virus
GO_0060337	Biological process	type I interferon-mediated signaling pathway
GO_0032696	Biological process	negative regulation of interleukin-13 production
GO_0006915	Biological process	apoptotic process
GO_0042100	Biological process	B cell proliferation
GO_0032714	Biological process	negative regulation of interleukin-5 production
GO_0002323	Biological process	natural killer cell activation involved in immune response
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0030183	Biological process	B cell differentiation
GO_0002286	Biological process	T cell activation involved in immune response
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0005132	Molecular function	type I interferon receptor binding
GO_0005125	Molecular function	cytokine activity
GO_0005515	Molecular function	protein binding

Gene name	IFNA2
Protein name	Interferon alpha-2 (IFN-alpha-2) (Interferon alpha-A) (LeIF A)
Synonyms	IFNA2B IFNA2A IFNA2C
Description	FUNCTION: Produced by macrophages, IFN-alpha have antiviral activities. .
Accessions	P01563 ENST00000380206.4

IFNA2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review