FOSL2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	35 studies	30% ± 10%	Explore
natural killer cell	27 studies	26% ± 9%	Explore
classical monocyte	23 studies	35% ± 16%	Explore
macrophage	22 studies	30% ± 11%	Explore
mast cell	21 studies	32% ± 15%	Explore
smooth muscle cell	18 studies	27% ± 10%	Explore
fibroblast	17 studies	25% ± 8%	Explore
pericyte	17 studies	35% ± 16%	Explore
monocyte	16 studies	29% ± 14%	Explore
conventional dendritic cell	14 studies	28% ± 11%	Explore
non-classical monocyte	12 studies	34% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	25% ± 8%	Explore
endothelial cell of vascular tree	12 studies	36% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	31% ± 14%	Explore
endothelial cell of artery	10 studies	25% ± 8%	Explore
dendritic cell	9 studies	32% ± 15%	Explore
vein endothelial cell	9 studies	30% ± 15%	Explore
neutrophil	8 studies	30% ± 10%	Explore
mucosal invariant T cell	8 studies	23% ± 6%	Explore
myeloid cell	8 studies	35% ± 17%	Explore
T cell	7 studies	31% ± 15%	Explore
mature NK T cell	7 studies	26% ± 10%	Explore
epithelial cell	7 studies	42% ± 23%	Explore
basal cell	7 studies	34% ± 18%	Explore
gamma-delta T cell	7 studies	31% ± 15%	Explore
innate lymphoid cell	6 studies	28% ± 9%	Explore
secretory cell	6 studies	21% ± 4%	Explore
connective tissue cell	6 studies	22% ± 6%	Explore
type I pneumocyte	5 studies	22% ± 3%	Explore
mononuclear phagocyte	5 studies	33% ± 12%	Explore
capillary endothelial cell	5 studies	26% ± 10%	Explore
ciliated cell	5 studies	30% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	32% ± 14%	Explore
leukocyte	5 studies	31% ± 5%	Explore
squamous epithelial cell	4 studies	46% ± 18%	Explore
renal principal cell	4 studies	36% ± 12%	Explore
mesothelial cell	4 studies	25% ± 7%	Explore
CD8-positive, alpha-beta T cell	4 studies	23% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	34% ± 10%	Explore
myofibroblast cell	4 studies	25% ± 8%	Explore
endothelial cell of lymphatic vessel	3 studies	22% ± 3%	Explore
glomerular endothelial cell	3 studies	18% ± 1%	Explore
extravillous trophoblast	3 studies	20% ± 1%	Explore
CD4-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
tissue-resident macrophage	3 studies	33% ± 15%	Explore
regulatory T cell	3 studies	17% ± 2%	Explore
muscle cell	3 studies	31% ± 1%	Explore
hematopoietic precursor cell	3 studies	27% ± 10%	Explore
goblet cell	3 studies	27% ± 8%	Explore
adventitial cell	3 studies	20% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	22% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	8 studies	28% ± 10%	Explore
intestine	6 studies	17% ± 2%	Explore
uterus	5 studies	31% ± 6%	Explore
peripheral blood	4 studies	24% ± 4%	Explore
breast	4 studies	18% ± 3%	Explore
placenta	3 studies	21% ± 6%	Explore
liver	3 studies	19% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	35885.24	180 / 180	99%	112.40	426 / 430
breast	100%	23180.92	459 / 459	99%	88.81	1104 / 1118
lung	100%	22732.69	576 / 578	99%	116.22	1143 / 1155
esophagus	98%	23251.66	1423 / 1445	100%	169.77	183 / 183
uterus	99%	23935.02	169 / 170	99%	125.80	454 / 459
bladder	100%	24103.38	21 / 21	98%	112.78	495 / 504
stomach	99%	18112.04	356 / 359	99%	88.41	282 / 286
intestine	99%	17685.03	952 / 966	99%	79.35	520 / 527
kidney	96%	13225.71	85 / 89	99%	126.36	890 / 901
prostate	97%	15593.29	237 / 245	96%	59.21	480 / 502
adrenal gland	100%	44711.59	258 / 258	85%	92.02	196 / 230
thymus	95%	10643.41	619 / 653	85%	49.59	514 / 605
skin	100%	25260.32	1809 / 1809	67%	29.39	316 / 472
pancreas	45%	3645.91	148 / 328	96%	101.64	170 / 178
adipose	100%	33760.33	1204 / 1204	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	37.94	1 / 1
blood vessel	100%	32671.13	1334 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	136.89	44 / 45
spleen	90%	9108.16	216 / 241	0%	0	0 / 0
muscle	89%	17071.87	716 / 803	0%	0	0 / 0
brain	25%	1758.23	665 / 2642	60%	28.26	422 / 705
heart	83%	10930.19	711 / 861	0%	0	0 / 0
peripheral blood	80%	19394.10	739 / 929	0%	0	0 / 0
liver	33%	3026.78	75 / 226	39%	18.07	160 / 406
lymph node	0%	0	0 / 0	24%	7.79	7 / 29
eye	0%	0	0 / 0	15%	4.08	12 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0048146	Biological process	positive regulation of fibroblast proliferation
GO_0003417	Biological process	growth plate cartilage development
GO_0030223	Biological process	neutrophil differentiation
GO_0140459	Biological process	response to Gram-positive bacterium
GO_1990823	Biological process	response to leukemia inhibitory factor
GO_0008219	Biological process	cell death
GO_0030316	Biological process	osteoclast differentiation
GO_1904760	Biological process	regulation of myofibroblast differentiation
GO_0045087	Biological process	innate immune response
GO_0030225	Biological process	macrophage differentiation
GO_0001649	Biological process	osteoblast differentiation
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0002062	Biological process	chondrocyte differentiation
GO_0035988	Biological process	chondrocyte proliferation
GO_0035264	Biological process	multicellular organism growth
GO_0060427	Biological process	lung connective tissue development
GO_0032496	Biological process	response to lipopolysaccharide
GO_0040014	Biological process	regulation of multicellular organism growth
GO_0001865	Biological process	NK T cell differentiation
GO_0050852	Biological process	T cell receptor signaling pathway
GO_0002437	Biological process	inflammatory response to antigenic stimulus
GO_0048873	Biological process	homeostasis of number of cells within a tissue
GO_0036446	Biological process	myofibroblast differentiation
GO_0048771	Biological process	tissue remodeling
GO_1904975	Biological process	response to bleomycin
GO_0060613	Biological process	fat pad development
GO_0051384	Biological process	response to glucocorticoid
GO_0098760	Biological process	response to interleukin-7
GO_0001666	Biological process	response to hypoxia
GO_0030282	Biological process	bone mineralization
GO_1901142	Biological process	insulin metabolic process
GO_0003334	Biological process	keratinocyte development
GO_0042100	Biological process	B cell proliferation
GO_0010467	Biological process	gene expression
GO_0000902	Biological process	cell morphogenesis
GO_0061144	Biological process	alveolar secondary septum development
GO_0048745	Biological process	smooth muscle tissue development
GO_0009410	Biological process	response to xenobiotic stimulus
GO_0035962	Biological process	response to interleukin-13
GO_0070254	Biological process	mucus secretion
GO_1904606	Biological process	fat cell apoptotic process
GO_0032964	Biological process	collagen biosynthetic process
GO_0030183	Biological process	B cell differentiation
GO_0042593	Biological process	glucose homeostasis
GO_0045444	Biological process	fat cell differentiation
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0090575	Cellular component	RNA polymerase II transcription regulator complex
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977	Molecular function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003682	Molecular function	chromatin binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	FOSL2
Protein name	Alternative protein FOSL2 (FOS-like antigen 2, isoform CRA_a) (cDNA: FLJ23306 fis, clone HEP11541) Fos-related antigen 2 (FRA-2) FOS like 2, AP-1 transcription factor subunit
Synonyms	FLJ23306 FRA2 hCG_1990537
Description	FUNCTION: Controls osteoclast survival and size (By similarity). As a dimer with JUN, activates LIF transcription (By similarity). Activates CEBPB transcription in PGE2-activated osteoblasts (By similarity). .
Accessions	P15408 ENST00000436647.1 Q9H5M2 C9JCN8 ENST00000379619.5 [P15408-2] ENST00000264716.9 [P15408-1]

FOSL2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review