CLCF1 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	3 studies	28% ± 16%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLCF1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	99%	561.48	178 / 180	100%	50.49	429 / 430
kidney	100%	1278.66	89 / 89	94%	33.80	843 / 901
lung	99%	782.29	573 / 578	91%	23.13	1051 / 1155
prostate	98%	659.47	241 / 245	89%	11.39	445 / 502
esophagus	95%	669.08	1378 / 1445	91%	17.57	167 / 183
intestine	100%	923.82	964 / 966	85%	13.19	449 / 527
thymus	100%	909.30	651 / 653	84%	27.56	508 / 605
uterus	99%	1548.97	169 / 170	84%	21.17	385 / 459
pancreas	87%	311.92	284 / 328	94%	34.75	167 / 178
breast	100%	477.28	457 / 459	81%	11.89	903 / 1118
bladder	100%	629.57	21 / 21	79%	17.58	399 / 504
stomach	88%	795.91	316 / 359	86%	13.86	246 / 286
skin	78%	547.03	1407 / 1809	41%	6.11	193 / 472
spleen	100%	698.04	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	11.89	1 / 1
adipose	99%	855.76	1197 / 1204	0%	0	0 / 0
blood vessel	99%	765.50	1325 / 1335	0%	0	0 / 0
liver	36%	158.42	81 / 226	50%	9.37	204 / 406
adrenal gland	76%	409.01	196 / 258	9%	1.41	21 / 230
heart	75%	398.16	647 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	59%	6.58	17 / 29
peripheral blood	53%	153.93	489 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	51%	5.35	23 / 45
brain	7%	44.74	190 / 2642	32%	6.75	228 / 705
muscle	12%	27.16	95 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	1%	0.12	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0042531	Biological process	positive regulation of tyrosine phosphorylation of STAT protein
GO_0019221	Biological process	cytokine-mediated signaling pathway
GO_0002639	Biological process	positive regulation of immunoglobulin production
GO_0048711	Biological process	positive regulation of astrocyte differentiation
GO_0030890	Biological process	positive regulation of B cell proliferation
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0043524	Biological process	negative regulation of neuron apoptotic process
GO_0048295	Biological process	positive regulation of isotype switching to IgE isotypes
GO_0007259	Biological process	cell surface receptor signaling pathway via JAK-STAT
GO_0030183	Biological process	B cell differentiation
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0097058	Cellular component	CRLF-CLCF1 complex
GO_0097059	Cellular component	CNTFR-CLCF1 complex
GO_0005102	Molecular function	signaling receptor binding
GO_0008083	Molecular function	growth factor activity
GO_0005127	Molecular function	ciliary neurotrophic factor receptor binding
GO_0005515	Molecular function	protein binding
GO_0005125	Molecular function	cytokine activity

Gene name	CLCF1
Protein name	Cardiotrophin-like cytokine factor 1 (B-cell-stimulating factor 3) (BSF-3) (Novel neurotrophin-1) (NNT-1)
Synonyms	NNT1 BSF3 CLC
Description	FUNCTION: In complex with CRLF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (Probable). Also stimulates B-cells. Binds to and activates the ILST/gp130 receptor. .
Accessions	Q9UBD9 ENST00000533438.1 [Q9UBD9-2] ENST00000312438.8 [Q9UBD9-1]

CLCF1 report