Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 16 studies | 26% ± 10% | |
goblet cell | 7 studies | 26% ± 9% | |
endothelial cell | 7 studies | 22% ± 6% | |
pericyte | 7 studies | 19% ± 3% | |
plasma cell | 6 studies | 30% ± 10% | |
connective tissue cell | 6 studies | 29% ± 16% | |
epithelial cell | 5 studies | 40% ± 20% | |
plasmablast | 4 studies | 41% ± 20% | |
secretory cell | 4 studies | 24% ± 6% | |
myofibroblast cell | 4 studies | 19% ± 3% | |
conventional dendritic cell | 3 studies | 18% ± 3% | |
placental villous trophoblast | 3 studies | 22% ± 3% | |
ciliated cell | 3 studies | 28% ± 5% | |
basal cell | 3 studies | 37% ± 4% | |
dendritic cell | 3 studies | 20% ± 4% | |
plasmacytoid dendritic cell | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 5 studies | 22% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 7530.69 | 328 / 328 | 100% | 236.91 | 178 / 178 |
prostate | 100% | 8122.93 | 245 / 245 | 100% | 483.21 | 501 / 502 |
liver | 100% | 6133.86 | 226 / 226 | 100% | 207.06 | 405 / 406 |
skin | 100% | 7102.41 | 1809 / 1809 | 100% | 304.37 | 470 / 472 |
breast | 100% | 6440.54 | 459 / 459 | 99% | 281.39 | 1112 / 1118 |
lung | 100% | 8041.07 | 578 / 578 | 99% | 235.61 | 1148 / 1155 |
stomach | 100% | 7209.79 | 359 / 359 | 99% | 161.94 | 284 / 286 |
thymus | 100% | 9094.78 | 653 / 653 | 99% | 216.51 | 600 / 605 |
uterus | 100% | 6328.43 | 170 / 170 | 99% | 241.12 | 454 / 459 |
bladder | 100% | 5173.90 | 21 / 21 | 99% | 234.14 | 497 / 504 |
intestine | 100% | 6903.92 | 966 / 966 | 98% | 202.75 | 518 / 527 |
esophagus | 100% | 4934.75 | 1445 / 1445 | 97% | 108.05 | 178 / 183 |
brain | 97% | 2893.15 | 2564 / 2642 | 100% | 154.52 | 702 / 705 |
adrenal gland | 100% | 9344.72 | 258 / 258 | 97% | 214.85 | 222 / 230 |
kidney | 100% | 5964.85 | 89 / 89 | 96% | 125.97 | 866 / 901 |
ovary | 100% | 4813.07 | 180 / 180 | 94% | 102.76 | 404 / 430 |
adipose | 100% | 6150.69 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 125.43 | 29 / 29 |
spleen | 100% | 5907.39 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 171.75 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 228.79 | 1 / 1 |
blood vessel | 100% | 6115.21 | 1332 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 210.66 | 79 / 80 |
heart | 98% | 5248.71 | 844 / 861 | 0% | 0 | 0 / 0 |
muscle | 94% | 2106.71 | 753 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 88% | 2926.33 | 816 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0098773 | Biological process | skin epidermis development |
GO_0071577 | Biological process | zinc ion transmembrane transport |
GO_0006882 | Biological process | intracellular zinc ion homeostasis |
GO_0110075 | Biological process | regulation of ferroptosis |
GO_0030183 | Biological process | B cell differentiation |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005385 | Molecular function | zinc ion transmembrane transporter activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SLC39A7 |
Protein name | Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) |
Synonyms | HKE4 RING5 |
Description | FUNCTION: Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels . Acts as a gatekeeper of zinc release from intracellular stores, requiring post-translational activation by phosphorylation, resulting in activation of multiple downstream pathways leading to cell growth and proliferation . Has an essential role in B cell development and is required for proper B cell receptor signaling . Plays an important role in maintaining intestinal epithelial homeostasis and skin dermis development by regulating ER function (By similarity). Controls cell signaling pathways involved in glucose metabolism in skeletal muscle (By similarity). Has a protective role against ER stress in different biological contexts . Mediates Zn(2+)-induced ferroptosis . . |
Accessions | ENST00000418477.6 ENST00000416369.6 ENST00000374675.7 ENST00000374677.8 A0A8V8TNV9 ENST00000425069.5 A0A8V8TM53 ENST00000414916.5 ENST00000698687.1 ENST00000443773.6 ENST00000698688.1 ENST00000414757.5 ENST00000441854.6 ENST00000383214.8 ENST00000698680.1 Q92504 A2AAT0 ENST00000429042.5 ENST00000423043.6 ENST00000444757.5 A0A8V8TM21 ENST00000383213.8 ENST00000456261.6 ENST00000441953.6 ENST00000431735.6 ENST00000454420.5 |