CD79B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0006955Biological processimmune response
GO_0002250Biological processadaptive immune response
GO_0050853Biological processB cell receptor signaling pathway
GO_0030183Biological processB cell differentiation
GO_0071755Cellular componentIgM B cell receptor complex
GO_0070062Cellular componentextracellular exosome
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0019815Cellular componentB cell receptor complex
GO_0004888Molecular functiontransmembrane signaling receptor activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCD79B
Protein nameB-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b)
CD79B protein
B-cell antigen receptor complex-associated protein beta chain isoform 3
SynonymsIGB
B29
DescriptionFUNCTION: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. .

AccessionsP40259
ENST00000006750.8 [P40259-1]
A0A192GQF2
Q6PIS4
ENST00000392795.7 [P40259-3]
ENST00000349817.2 [P40259-2]