Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 45 studies | 60% ± 23% | |
memory B cell | 20 studies | 63% ± 15% | |
naive B cell | 20 studies | 67% ± 15% | |
non-classical monocyte | 14 studies | 36% ± 15% | |
plasma cell | 13 studies | 40% ± 15% | |
plasmablast | 8 studies | 53% ± 19% | |
regulatory T cell | 8 studies | 22% ± 6% | |
precursor B cell | 7 studies | 83% ± 15% | |
immature B cell | 7 studies | 87% ± 7% | |
pro-B cell | 5 studies | 77% ± 16% | |
germinal center B cell | 4 studies | 73% ± 17% | |
IgG plasma cell | 4 studies | 26% ± 10% | |
follicular B cell | 3 studies | 74% ± 15% | |
IgM plasma cell | 3 studies | 49% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 443.27 | 458 / 459 | 78% | 5.56 | 873 / 1118 |
prostate | 93% | 272.50 | 229 / 245 | 83% | 3.04 | 418 / 502 |
lung | 91% | 205.23 | 524 / 578 | 83% | 5.37 | 960 / 1155 |
thymus | 75% | 272.41 | 492 / 653 | 91% | 10.35 | 548 / 605 |
uterus | 98% | 360.62 | 167 / 170 | 67% | 3.12 | 308 / 459 |
kidney | 87% | 253.72 | 77 / 89 | 73% | 3.63 | 661 / 901 |
bladder | 90% | 349.71 | 19 / 21 | 67% | 16.24 | 336 / 504 |
skin | 65% | 223.75 | 1173 / 1809 | 82% | 13.04 | 386 / 472 |
intestine | 79% | 966.95 | 767 / 966 | 67% | 7.89 | 353 / 527 |
stomach | 75% | 150.36 | 268 / 359 | 64% | 7.29 | 182 / 286 |
esophagus | 86% | 195.13 | 1240 / 1445 | 43% | 1.68 | 79 / 183 |
liver | 42% | 64.27 | 96 / 226 | 76% | 3.46 | 309 / 406 |
adrenal gland | 56% | 74.22 | 145 / 258 | 59% | 1.61 | 136 / 230 |
lymph node | 0% | 0 | 0 / 0 | 100% | 926.31 | 29 / 29 |
spleen | 100% | 9057.79 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 3256.94 | 926 / 929 | 0% | 0 | 0 / 0 |
adipose | 99% | 402.41 | 1191 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 28.14 | 79 / 80 |
pancreas | 8% | 9.55 | 27 / 328 | 86% | 11.53 | 153 / 178 |
tonsil | 0% | 0 | 0 / 0 | 87% | 13.07 | 39 / 45 |
heart | 77% | 207.80 | 665 / 861 | 0% | 0 | 0 / 0 |
muscle | 71% | 108.87 | 571 / 803 | 0% | 0 | 0 / 0 |
ovary | 16% | 32.06 | 29 / 180 | 45% | 1.16 | 195 / 430 |
blood vessel | 53% | 154.78 | 713 / 1335 | 0% | 0 | 0 / 0 |
brain | 1% | 1.10 | 23 / 2642 | 11% | 1.90 | 77 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0006955 | Biological process | immune response |
GO_0002250 | Biological process | adaptive immune response |
GO_0050853 | Biological process | B cell receptor signaling pathway |
GO_0030183 | Biological process | B cell differentiation |
GO_0071755 | Cellular component | IgM B cell receptor complex |
GO_0070062 | Cellular component | extracellular exosome |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0019815 | Cellular component | B cell receptor complex |
GO_0004888 | Molecular function | transmembrane signaling receptor activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CD79B |
Protein name | B-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b) CD79B protein B-cell antigen receptor complex-associated protein beta chain isoform 3 |
Synonyms | IGB B29 |
Description | FUNCTION: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. . |
Accessions | P40259 ENST00000006750.8 [P40259-1] A0A192GQF2 Q6PIS4 ENST00000392795.7 [P40259-3] ENST00000349817.2 [P40259-2] |