F3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
basal cell	19 studies	50% ± 20%	Explore
astrocyte	17 studies	45% ± 19%	Explore
fibroblast	14 studies	31% ± 16%	Explore
type I pneumocyte	10 studies	35% ± 14%	Explore
type II pneumocyte	10 studies	37% ± 15%	Explore
epithelial cell	9 studies	38% ± 16%	Explore
adipocyte	9 studies	33% ± 11%	Explore
secretory cell	8 studies	49% ± 26%	Explore
respiratory goblet cell	7 studies	67% ± 20%	Explore
club cell	6 studies	60% ± 16%	Explore
goblet cell	6 studies	33% ± 16%	Explore
ciliated cell	6 studies	36% ± 18%	Explore
retinal pigment epithelial cell	5 studies	34% ± 10%	Explore
Mueller cell	5 studies	62% ± 14%	Explore
deuterosomal cell	4 studies	46% ± 14%	Explore
duct epithelial cell	4 studies	30% ± 14%	Explore
adventitial cell	4 studies	24% ± 6%	Explore
connective tissue cell	4 studies	33% ± 14%	Explore
squamous epithelial cell	3 studies	69% ± 11%	Explore
podocyte	3 studies	41% ± 18%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	7 studies	35% ± 21%	Explore
uterus	3 studies	27% ± 5%	Explore
prostate	3 studies	33% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	97%	7394.02	563 / 578	91%	140.52	1050 / 1155
prostate	97%	6011.26	237 / 245	90%	237.39	452 / 502
pancreas	81%	7474.98	265 / 328	93%	203.39	165 / 178
thymus	100%	8649.62	650 / 653	73%	61.05	441 / 605
stomach	92%	4194.82	329 / 359	74%	48.26	212 / 286
brain	76%	5150.10	2010 / 2642	89%	133.36	630 / 705
intestine	80%	4702.06	775 / 966	85%	63.96	448 / 527
esophagus	67%	2413.82	961 / 1445	86%	73.90	157 / 183
bladder	86%	8097.05	18 / 21	63%	84.73	318 / 504
breast	100%	9231.26	458 / 459	47%	27.81	525 / 1118
uterus	69%	3521.46	118 / 170	72%	159.30	330 / 459
adrenal gland	79%	2420.15	205 / 258	43%	27.06	100 / 230
ovary	96%	14421.88	172 / 180	18%	7.50	77 / 430
skin	99%	7054.55	1792 / 1809	7%	3.08	35 / 472
ureter	0%	0	0 / 0	100%	20.26	1 / 1
adipose	100%	12517.73	1201 / 1204	0%	0	0 / 0
blood vessel	82%	3325.18	1089 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	80%	88.36	36 / 45
kidney	58%	1464.92	52 / 89	10%	6.35	87 / 901
heart	51%	1202.98	443 / 861	0%	0	0 / 0
spleen	20%	526.90	49 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	10%	3.84	3 / 29
liver	3%	58.24	7 / 226	7%	4.01	28 / 406
muscle	8%	159.32	68 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	3%	1.28	2 / 80
peripheral blood	0%	4.51	2 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0019221	Biological process	cytokine-mediated signaling pathway
GO_0006919	Biological process	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO_0010641	Biological process	positive regulation of platelet-derived growth factor receptor signaling pathway
GO_0045766	Biological process	positive regulation of angiogenesis
GO_0010628	Biological process	positive regulation of gene expression
GO_0016485	Biological process	protein processing
GO_0002541	Biological process	activation of plasma proteins involved in acute inflammatory response
GO_0007596	Biological process	blood coagulation
GO_0001938	Biological process	positive regulation of endothelial cell proliferation
GO_0030335	Biological process	positive regulation of cell migration
GO_0032757	Biological process	positive regulation of interleukin-8 production
GO_0050927	Biological process	positive regulation of positive chemotaxis
GO_0032008	Biological process	positive regulation of TOR signaling
GO_0002543	Biological process	activation of blood coagulation via clotting cascade
GO_0005615	Cellular component	extracellular space
GO_0009897	Cellular component	external side of plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_1905286	Cellular component	serine-type peptidase complex
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0009986	Cellular component	cell surface
GO_0005543	Molecular function	phospholipid binding
GO_0002020	Molecular function	protease binding
GO_0004896	Molecular function	cytokine receptor activity
GO_0005515	Molecular function	protein binding
GO_0004252	Molecular function	serine-type endopeptidase activity

IV. Literature review

[source]

Gene name	F3
Protein name	Tissue factor (TF) (Coagulation factor III) (Thromboplastin) (CD antigen CD142)
Synonyms
Description	FUNCTION: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. .
Accessions	P13726 ENST00000334047.12 [P13726-1] ENST00000370207.4 [P13726-2]

F3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review