Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 32 studies | 40% ± 17% | |
astrocyte | 17 studies | 37% ± 17% | |
microglial cell | 14 studies | 41% ± 12% | |
oligodendrocyte precursor cell | 13 studies | 42% ± 17% | |
glutamatergic neuron | 12 studies | 57% ± 24% | |
fibroblast | 12 studies | 32% ± 13% | |
oligodendrocyte | 12 studies | 32% ± 12% | |
GABAergic neuron | 11 studies | 54% ± 24% | |
pericyte | 11 studies | 35% ± 12% | |
macrophage | 11 studies | 37% ± 17% | |
adipocyte | 10 studies | 61% ± 19% | |
T cell | 8 studies | 31% ± 12% | |
epithelial cell | 8 studies | 41% ± 17% | |
smooth muscle cell | 8 studies | 32% ± 10% | |
neuron | 7 studies | 46% ± 24% | |
endothelial cell of artery | 7 studies | 26% ± 5% | |
B cell | 7 studies | 29% ± 10% | |
endothelial cell of lymphatic vessel | 7 studies | 34% ± 12% | |
natural killer cell | 6 studies | 31% ± 9% | |
interneuron | 6 studies | 64% ± 18% | |
ciliated cell | 6 studies | 29% ± 10% | |
plasma cell | 5 studies | 38% ± 9% | |
CD8-positive, alpha-beta T cell | 5 studies | 32% ± 10% | |
capillary endothelial cell | 5 studies | 32% ± 15% | |
cardiac muscle cell | 5 studies | 41% ± 13% | |
dendritic cell | 5 studies | 26% ± 7% | |
mesothelial cell | 5 studies | 35% ± 12% | |
basal cell | 5 studies | 38% ± 20% | |
myeloid cell | 5 studies | 29% ± 6% | |
monocyte | 5 studies | 35% ± 6% | |
type I pneumocyte | 5 studies | 39% ± 8% | |
type II pneumocyte | 5 studies | 31% ± 8% | |
granule cell | 4 studies | 44% ± 9% | |
CD4-positive, alpha-beta T cell | 4 studies | 34% ± 10% | |
lymphocyte | 4 studies | 41% ± 21% | |
Mueller cell | 4 studies | 36% ± 9% | |
amacrine cell | 4 studies | 36% ± 7% | |
retina horizontal cell | 4 studies | 37% ± 10% | |
retinal cone cell | 4 studies | 32% ± 8% | |
retinal ganglion cell | 4 studies | 40% ± 16% | |
retinal rod cell | 4 studies | 27% ± 4% | |
endothelial cell of vascular tree | 4 studies | 40% ± 24% | |
mast cell | 4 studies | 37% ± 16% | |
club cell | 4 studies | 36% ± 12% | |
GABAergic interneuron | 3 studies | 55% ± 2% | |
glial cell | 3 studies | 26% ± 11% | |
progenitor cell | 3 studies | 31% ± 9% | |
vein endothelial cell | 3 studies | 38% ± 18% | |
GABAergic amacrine cell | 3 studies | 43% ± 11% | |
glycinergic amacrine cell | 3 studies | 33% ± 6% | |
CD8-positive, alpha-beta memory T cell | 3 studies | 32% ± 17% | |
Schwann cell | 3 studies | 30% ± 13% | |
chondrocyte | 3 studies | 32% ± 5% | |
regulatory T cell | 3 studies | 25% ± 5% | |
hepatocyte | 3 studies | 47% ± 17% | |
ependymal cell | 3 studies | 49% ± 19% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 35% ± 18% | |
myofibroblast cell | 3 studies | 34% ± 14% | |
alveolar macrophage | 3 studies | 40% ± 7% | |
respiratory goblet cell | 3 studies | 38% ± 16% | |
leukocyte | 3 studies | 54% ± 14% | |
transit amplifying cell | 3 studies | 38% ± 30% | |
CD4-positive, alpha-beta memory T cell | 3 studies | 20% ± 2% | |
mural cell | 3 studies | 48% ± 8% | |
mucus secreting cell | 3 studies | 33% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4816.40 | 1445 / 1445 | 100% | 31.63 | 183 / 183 |
ovary | 100% | 6129.74 | 180 / 180 | 100% | 25.68 | 430 / 430 |
prostate | 100% | 4491.76 | 245 / 245 | 100% | 20.33 | 502 / 502 |
lung | 100% | 3773.32 | 577 / 578 | 100% | 23.32 | 1154 / 1155 |
breast | 100% | 4912.75 | 459 / 459 | 100% | 25.61 | 1114 / 1118 |
brain | 100% | 2720.45 | 2632 / 2642 | 100% | 23.59 | 705 / 705 |
thymus | 100% | 4659.16 | 653 / 653 | 99% | 19.39 | 601 / 605 |
bladder | 100% | 5312.38 | 21 / 21 | 99% | 20.32 | 500 / 504 |
uterus | 100% | 5112.49 | 170 / 170 | 99% | 20.07 | 454 / 459 |
stomach | 100% | 3897.00 | 359 / 359 | 99% | 22.28 | 282 / 286 |
pancreas | 99% | 1709.84 | 325 / 328 | 99% | 17.14 | 177 / 178 |
intestine | 100% | 4299.58 | 966 / 966 | 98% | 18.13 | 518 / 527 |
kidney | 100% | 2650.76 | 89 / 89 | 97% | 20.52 | 877 / 901 |
adrenal gland | 100% | 2841.12 | 257 / 258 | 96% | 12.88 | 221 / 230 |
skin | 100% | 3640.82 | 1807 / 1809 | 95% | 21.75 | 447 / 472 |
liver | 100% | 1684.41 | 226 / 226 | 90% | 10.33 | 366 / 406 |
adipose | 100% | 5896.82 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5354.72 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 17.52 | 29 / 29 |
spleen | 100% | 3816.95 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 20.60 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.03 | 1 / 1 |
muscle | 100% | 3781.39 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 2267.88 | 854 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 75.17 | 79 / 80 |
peripheral blood | 72% | 1298.46 | 668 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0019221 | Biological process | cytokine-mediated signaling pathway |
GO_0061384 | Biological process | heart trabecula morphogenesis |
GO_0007265 | Biological process | Ras protein signal transduction |
GO_2000973 | Biological process | regulation of pro-B cell differentiation |
GO_0002931 | Biological process | response to ischemia |
GO_1904693 | Biological process | midbrain morphogenesis |
GO_0042552 | Biological process | myelination |
GO_0048011 | Biological process | neurotrophin TRK receptor signaling pathway |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0048009 | Biological process | insulin-like growth factor receptor signaling pathway |
GO_0007165 | Biological process | signal transduction |
GO_0042129 | Biological process | regulation of T cell proliferation |
GO_0050853 | Biological process | B cell receptor signaling pathway |
GO_0035264 | Biological process | multicellular organism growth |
GO_0038095 | Biological process | Fc-epsilon receptor signaling pathway |
GO_0001782 | Biological process | B cell homeostasis |
GO_0003344 | Biological process | pericardium morphogenesis |
GO_0003209 | Biological process | cardiac atrium morphogenesis |
GO_0045742 | Biological process | positive regulation of epidermal growth factor receptor signaling pathway |
GO_0060021 | Biological process | roof of mouth development |
GO_0008286 | Biological process | insulin receptor signaling pathway |
GO_0014044 | Biological process | Schwann cell development |
GO_0050900 | Biological process | leukocyte migration |
GO_0001942 | Biological process | hair follicle development |
GO_0051057 | Biological process | positive regulation of small GTPase mediated signal transduction |
GO_0007173 | Biological process | epidermal growth factor receptor signaling pathway |
GO_0007296 | Biological process | vitellogenesis |
GO_0048514 | Biological process | blood vessel morphogenesis |
GO_0033081 | Biological process | regulation of T cell differentiation in thymus |
GO_0061029 | Biological process | eyelid development in camera-type eye |
GO_0042127 | Biological process | regulation of cell population proliferation |
GO_0007411 | Biological process | axon guidance |
GO_0008543 | Biological process | fibroblast growth factor receptor signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_1905360 | Cellular component | GTPase complex |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005154 | Molecular function | epidermal growth factor receptor binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0140693 | Molecular function | molecular condensate scaffold activity |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0005515 | Molecular function | protein binding |
GO_0017124 | Molecular function | SH3 domain binding |
Gene name | SOS1 |
Protein name | SOS1 Uncharacterized protein SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 Alternate SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 (Son of sevenless homolog 1 (Drosophila), isoform CRA_d) Son of sevenless homolog 1 (SOS-1) |
Synonyms | hCG_1641052 |
Description | FUNCTION: Promotes the exchange of Ras-bound GDP by GTP . Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF . Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity). . |
Accessions | A0A8I5KWL0 ENST00000690876.1 ENST00000402219.8 [Q07889-1] A0A3G1LBG1 A0A8I5KY52 ENST00000692089.1 Q9UKX9 Q53SF8 ENST00000690679.1 ENST00000692620.1 A0A8I5QJ77 ENST00000395038.6 A0A8I5KV97 A0A2X0SG47 A0A8I5QJD1 ENST00000692227.1 C9K0N6 A0A8I5KP47 ENST00000691229.1 Q07889 A0A8I5QJF3 ENST00000451331.1 Q8NIA3 ENST00000685279.1 G5E9C8 |