Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 47 studies | 43% ± 20% | |
fibroblast | 21 studies | 30% ± 16% | |
astrocyte | 17 studies | 60% ± 21% | |
oligodendrocyte | 15 studies | 45% ± 17% | |
vein endothelial cell | 15 studies | 52% ± 20% | |
capillary endothelial cell | 13 studies | 38% ± 12% | |
endothelial cell of artery | 13 studies | 42% ± 14% | |
endothelial cell of vascular tree | 12 studies | 44% ± 16% | |
oligodendrocyte precursor cell | 11 studies | 44% ± 20% | |
GABAergic neuron | 8 studies | 33% ± 16% | |
pericyte | 8 studies | 23% ± 8% | |
adipocyte | 6 studies | 30% ± 17% | |
type II pneumocyte | 5 studies | 26% ± 10% | |
endothelial cell of sinusoid | 4 studies | 51% ± 23% | |
glomerular endothelial cell | 4 studies | 62% ± 4% | |
interneuron | 4 studies | 33% ± 17% | |
cardiac muscle cell | 4 studies | 20% ± 1% | |
glutamatergic neuron | 4 studies | 46% ± 17% | |
connective tissue cell | 4 studies | 36% ± 21% | |
club cell | 4 studies | 24% ± 11% | |
endothelial cell of lymphatic vessel | 4 studies | 20% ± 3% | |
smooth muscle cell | 4 studies | 22% ± 3% | |
hepatic stellate cell | 3 studies | 44% ± 13% | |
neuron | 3 studies | 32% ± 22% | |
microglial cell | 3 studies | 33% ± 15% | |
retinal ganglion cell | 3 studies | 34% ± 10% | |
endocardial cell | 3 studies | 35% ± 10% | |
ependymal cell | 3 studies | 57% ± 14% | |
kidney loop of Henle epithelial cell | 3 studies | 30% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 7750.72 | 244 / 245 | 99% | 46.07 | 498 / 502 |
brain | 95% | 3967.21 | 2521 / 2642 | 100% | 64.59 | 702 / 705 |
kidney | 97% | 3702.47 | 86 / 89 | 90% | 23.27 | 808 / 901 |
adrenal gland | 99% | 4273.18 | 255 / 258 | 71% | 9.76 | 163 / 230 |
breast | 100% | 16926.03 | 459 / 459 | 69% | 10.38 | 775 / 1118 |
lung | 100% | 10367.91 | 577 / 578 | 69% | 13.79 | 798 / 1155 |
thymus | 100% | 13267.19 | 652 / 653 | 66% | 11.96 | 401 / 605 |
ovary | 100% | 7571.57 | 180 / 180 | 62% | 6.55 | 265 / 430 |
uterus | 99% | 16214.43 | 169 / 170 | 36% | 4.57 | 167 / 459 |
pancreas | 88% | 2962.02 | 290 / 328 | 42% | 4.14 | 74 / 178 |
esophagus | 84% | 4618.61 | 1220 / 1445 | 42% | 4.89 | 76 / 183 |
bladder | 100% | 5773.52 | 21 / 21 | 24% | 2.82 | 123 / 504 |
stomach | 100% | 7406.46 | 359 / 359 | 23% | 2.37 | 67 / 286 |
skin | 83% | 3441.77 | 1503 / 1809 | 24% | 7.39 | 111 / 472 |
intestine | 93% | 4765.72 | 895 / 966 | 11% | 1.28 | 60 / 527 |
blood vessel | 100% | 6420.95 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 15153.69 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 6397.79 | 801 / 803 | 0% | 0 | 0 / 0 |
spleen | 98% | 5606.70 | 236 / 241 | 0% | 0 | 0 / 0 |
heart | 94% | 3711.81 | 808 / 861 | 0% | 0 | 0 / 0 |
liver | 67% | 1909.54 | 152 / 226 | 14% | 1.44 | 55 / 406 |
tonsil | 0% | 0 | 0 / 0 | 33% | 6.62 | 15 / 45 |
lymph node | 0% | 0 | 0 / 0 | 24% | 1.83 | 7 / 29 |
eye | 0% | 0 | 0 / 0 | 3% | 0.15 | 2 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0019221 | Biological process | cytokine-mediated signaling pathway |
GO_0034097 | Biological process | response to cytokine |
GO_0038165 | Biological process | oncostatin-M-mediated signaling pathway |
GO_0070120 | Biological process | ciliary neurotrophic factor-mediated signaling pathway |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0048861 | Biological process | leukemia inhibitory factor signaling pathway |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0043235 | Cellular component | receptor complex |
GO_0005886 | Cellular component | plasma membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0004924 | Molecular function | oncostatin-M receptor activity |
GO_0004897 | Molecular function | ciliary neurotrophic factor receptor activity |
GO_0004923 | Molecular function | leukemia inhibitory factor receptor activity |
GO_0019955 | Molecular function | cytokine binding |
GO_0004896 | Molecular function | cytokine receptor activity |
GO_0019838 | Molecular function | growth factor binding |
GO_0005127 | Molecular function | ciliary neurotrophic factor receptor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | LIFR |
Protein name | Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118) LIF receptor subunit alpha Leukemia inhibitory factor receptor |
Synonyms | |
Description | FUNCTION: Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells. |
Accessions | P42702 H0YAF2 ENST00000506003.5 A0A411LPI4 D6RF33 D6RJ94 ENST00000506990.5 ENST00000511561.1 ENST00000453190.7 [P42702-1] ENST00000263409.8 [P42702-1] |