IL5RA | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	10 studies	27% ± 8%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of IL5RA at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	93%	126.30	227 / 245	48%	4.83	243 / 502
lung	99%	242.03	570 / 578	18%	0.52	204 / 1155
spleen	100%	146.61	241 / 241	0%	0	0 / 0
stomach	73%	22.51	263 / 359	1%	0.02	3 / 286
bladder	71%	26.48	15 / 21	2%	0.04	9 / 504
intestine	71%	36.44	682 / 966	1%	0.01	4 / 527
peripheral blood	70%	77.36	648 / 929	0%	0	0 / 0
esophagus	64%	23.86	923 / 1445	1%	0.01	1 / 183
adipose	61%	17.11	731 / 1204	0%	0	0 / 0
uterus	55%	51.30	93 / 170	4%	0.15	18 / 459
heart	51%	51.88	439 / 861	0%	0	0 / 0
breast	45%	11.32	205 / 459	3%	0.07	33 / 1118
kidney	46%	19.47	41 / 89	1%	0.02	10 / 901
skin	39%	10.11	705 / 1809	2%	0.04	9 / 472
thymus	39%	13.35	254 / 653	1%	0.01	5 / 605
ovary	16%	5.18	29 / 180	18%	0.66	76 / 430
brain	29%	60.14	767 / 2642	2%	0.21	15 / 705
blood vessel	21%	5.47	282 / 1335	0%	0	0 / 0
liver	16%	2.62	36 / 226	0%	0	0 / 406
pancreas	13%	2.17	43 / 328	2%	0.04	3 / 178
lymph node	0%	0	0 / 0	14%	0.60	4 / 29
adrenal gland	7%	1.10	17 / 258	3%	0.08	6 / 230
muscle	2%	0.30	15 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_0019221	Biological process	cytokine-mediated signaling pathway
GO_0002437	Biological process	inflammatory response to antigenic stimulus
GO_0032674	Biological process	regulation of interleukin-5 production
GO_0038043	Biological process	interleukin-5-mediated signaling pathway
GO_0070665	Biological process	positive regulation of leukocyte proliferation
GO_0005615	Cellular component	extracellular space
GO_0009897	Cellular component	external side of plasma membrane
GO_0043235	Cellular component	receptor complex
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0004914	Molecular function	interleukin-5 receptor activity
GO_0019955	Molecular function	cytokine binding
GO_0005515	Molecular function	protein binding
GO_0004896	Molecular function	cytokine receptor activity

Gene name	IL5RA
Protein name	Interleukin 5 receptor alpha transcript variant 7 Interleukin 5 receptor subunit alpha Interleukin-5 receptor subunit alpha (IL-5 receptor subunit alpha) (IL-5R subunit alpha) (IL-5R-alpha) (IL-5RA) (CDw125) (CD antigen CD125) Interleukin 5 receptor, alpha
Synonyms	IL5R
Description	FUNCTION: Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils . Acts by forming an heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 . In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway . .
Accessions	C9J6C4 ENST00000383846.5 [Q01344-2] ENST00000446632.7 [Q01344-1] Q01344 ENST00000438560.5 [Q01344-4] ENST00000430514.6 [Q01344-3] ENST00000456302.5 [Q01344-3] ENST00000311981.12 [Q01344-2] ENST00000256452.7 [Q01344-1] ENST00000418488.6 B3IU76 ENST00000445701.5 ENST00000427088.1 C9J3K8 Q8NHV7 E7ERY4

IL5RA report