CRLF1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042531Biological processpositive regulation of tyrosine phosphorylation of STAT protein
GO_0019221Biological processcytokine-mediated signaling pathway
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0001657Biological processureteric bud development
GO_0043524Biological processnegative regulation of neuron apoptotic process
GO_2000672Biological processnegative regulation of motor neuron apoptotic process
GO_0005615Cellular componentextracellular space
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005829Cellular componentcytosol
GO_0043235Cellular componentreceptor complex
GO_0005576Cellular componentextracellular region
GO_0097058Cellular componentCRLF-CLCF1 complex
GO_0005127Molecular functionciliary neurotrophic factor receptor binding
GO_0019955Molecular functioncytokine binding
GO_0005515Molecular functionprotein binding
GO_0004896Molecular functioncytokine receptor activity
GO_0005125Molecular functioncytokine activity

IV. Literature review

[source]
Gene nameCRLF1
Protein nameCytokine receptor like factor 1
Cytokine receptor-like factor 1 (Cytokine-like factor 1) (CLF-1) (ZcytoR5)
SynonymsUNQ288/PRO327
DescriptionFUNCTION: In complex with CLCF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (Probable). May also play a regulatory role in the immune system. .

AccessionsENST00000597131.1
O75462
M0QZL6
ENST00000392386.8
ENST00000684169.1
A0A804HI12