Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 38 studies | 37% ± 12% | |
| B cell | 31 studies | 26% ± 9% | |
| classical monocyte | 26 studies | 46% ± 15% | |
| non-classical monocyte | 23 studies | 49% ± 15% | |
| dendritic cell | 22 studies | 32% ± 13% | |
| monocyte | 21 studies | 41% ± 12% | |
| conventional dendritic cell | 21 studies | 32% ± 11% | |
| fibroblast | 21 studies | 27% ± 13% | |
| memory B cell | 18 studies | 29% ± 9% | |
| naive B cell | 15 studies | 28% ± 7% | |
| myeloid cell | 15 studies | 39% ± 12% | |
| endothelial cell | 14 studies | 27% ± 9% | |
| microglial cell | 13 studies | 31% ± 14% | |
| basal cell | 12 studies | 33% ± 13% | |
| epithelial cell | 10 studies | 43% ± 20% | |
| adipocyte | 9 studies | 35% ± 15% | |
| alveolar macrophage | 8 studies | 29% ± 10% | |
| endothelial cell of lymphatic vessel | 8 studies | 21% ± 4% | |
| pericyte | 8 studies | 22% ± 6% | |
| endothelial cell of vascular tree | 8 studies | 22% ± 4% | |
| type I pneumocyte | 8 studies | 23% ± 6% | |
| mononuclear phagocyte | 7 studies | 34% ± 15% | |
| club cell | 7 studies | 19% ± 3% | |
| ciliated cell | 7 studies | 27% ± 13% | |
| secretory cell | 7 studies | 44% ± 22% | |
| mast cell | 6 studies | 22% ± 3% | |
| neutrophil | 6 studies | 27% ± 9% | |
| leukocyte | 6 studies | 31% ± 6% | |
| abnormal cell | 6 studies | 30% ± 10% | |
| connective tissue cell | 6 studies | 28% ± 6% | |
| plasmablast | 5 studies | 25% ± 14% | |
| intermediate monocyte | 5 studies | 56% ± 17% | |
| astrocyte | 5 studies | 27% ± 10% | |
| GABAergic neuron | 4 studies | 30% ± 11% | |
| glutamatergic neuron | 4 studies | 34% ± 10% | |
| precursor B cell | 4 studies | 28% ± 9% | |
| immature B cell | 4 studies | 39% ± 11% | |
| luminal hormone-sensing cell of mammary gland | 4 studies | 27% ± 7% | |
| vein endothelial cell | 4 studies | 21% ± 4% | |
| luminal cell of prostate epithelium | 4 studies | 45% ± 16% | |
| enterocyte | 4 studies | 19% ± 3% | |
| goblet cell | 4 studies | 28% ± 13% | |
| interneuron | 4 studies | 38% ± 22% | |
| smooth muscle cell | 4 studies | 18% ± 3% | |
| plasma cell | 3 studies | 29% ± 12% | |
| plasmacytoid dendritic cell | 3 studies | 19% ± 3% | |
| retinal cone cell | 3 studies | 21% ± 4% | |
| glial cell | 3 studies | 29% ± 2% | |
| tissue-resident macrophage | 3 studies | 34% ± 6% | |
| chondrocyte | 3 studies | 25% ± 6% | |
| keratinocyte | 3 studies | 20% ± 7% | |
| melanocyte | 3 studies | 27% ± 6% | |
| inflammatory macrophage | 3 studies | 30% ± 12% | |
| granulocyte | 3 studies | 23% ± 4% | |
| type II pneumocyte | 3 studies | 19% ± 3% | |
| enteroendocrine cell | 3 studies | 23% ± 9% | |
| myofibroblast cell | 3 studies | 19% ± 5% | |
| oligodendrocyte | 3 studies | 26% ± 2% | |
| oligodendrocyte precursor cell | 3 studies | 28% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2554.20 | 1445 / 1445 | 100% | 65.14 | 183 / 183 |
| lung | 100% | 3777.54 | 578 / 578 | 100% | 99.19 | 1155 / 1155 |
| ovary | 100% | 2211.19 | 180 / 180 | 100% | 81.41 | 430 / 430 |
| prostate | 100% | 3005.06 | 245 / 245 | 100% | 104.08 | 502 / 502 |
| skin | 100% | 3088.80 | 1809 / 1809 | 100% | 111.78 | 472 / 472 |
| thymus | 100% | 3421.95 | 653 / 653 | 100% | 101.03 | 605 / 605 |
| breast | 100% | 4000.12 | 459 / 459 | 100% | 99.70 | 1117 / 1118 |
| intestine | 100% | 2559.84 | 966 / 966 | 100% | 92.94 | 526 / 527 |
| bladder | 100% | 2793.62 | 21 / 21 | 100% | 103.41 | 503 / 504 |
| uterus | 100% | 2194.46 | 170 / 170 | 100% | 93.11 | 458 / 459 |
| stomach | 100% | 1700.51 | 358 / 359 | 100% | 84.73 | 285 / 286 |
| kidney | 100% | 2556.57 | 89 / 89 | 99% | 80.02 | 891 / 901 |
| brain | 96% | 1495.41 | 2528 / 2642 | 100% | 57.59 | 703 / 705 |
| pancreas | 91% | 1058.57 | 299 / 328 | 99% | 115.83 | 177 / 178 |
| adrenal gland | 100% | 2340.95 | 258 / 258 | 90% | 34.94 | 208 / 230 |
| liver | 100% | 1350.83 | 225 / 226 | 85% | 40.03 | 345 / 406 |
| adipose | 100% | 4335.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 105.43 | 29 / 29 |
| peripheral blood | 100% | 8752.90 | 929 / 929 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4723.77 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 102.63 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 49.70 | 1 / 1 |
| blood vessel | 99% | 2351.71 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 1699.83 | 845 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 93% | 28.87 | 74 / 80 |
| muscle | 88% | 974.80 | 710 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009615 | Biological process | response to virus |
| GO_0019221 | Biological process | cytokine-mediated signaling pathway |
| GO_0098586 | Biological process | cellular response to virus |
| GO_0051607 | Biological process | defense response to virus |
| GO_0060333 | Biological process | type II interferon-mediated signaling pathway |
| GO_0001774 | Biological process | microglial cell activation |
| GO_0038196 | Biological process | type III interferon-mediated signaling pathway |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0004906 | Molecular function | type II interferon receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004896 | Molecular function | cytokine receptor activity |
| Gene name | IFNGR2 |
| Protein name | Interferon gamma receptor 2 (IFN-gamma receptor 2) (IFN-gamma-R2) (Interferon gamma receptor accessory factor 1) (AF-1) (Interferon gamma receptor beta-chain) (IFN-gamma-R-beta) (Interferon gamma transducer 1) Interferon gamma receptor 2 Interferon gamma receptor 2 (Interferon gamma transducer 1), isoform CRA_a (cDNA FLJ78008, highly similar to Human clone pSK1 interferon gamma receptor accessory factor-1 (AF-1) mRNA) (cDNA, FLJ94659, highly similar to Homo sapiens interferon gamma receptor 2 (interferon gammatransducer 1) (IFNGR2), mRNA) |
| Synonyms | hCG_401179 IFNGT1 |
| Description | FUNCTION: Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) . Ligand binding stimulates activation of the JAK/STAT signaling pathway . Required for signal transduction in contrast to other receptor subunit responsible for ligand binding . . |
| Accessions | A0A0G2JLC6 A0A0G2JLD7 ENST00000381995.5 ENST00000572016.5 A0A8Q3SIY7 ENST00000421802.1 ENST00000573887.2 F8WF11 F8WE34 P38484 A8K881 ENST00000696724.1 ENST00000545369.2 H7C1V5 B5MCZ0 ENST00000573079.5 ENST00000405436.5 E7EUY1 ENST00000576463.5 A0A0G2JLE8 ENST00000575304.1 ENST00000571550.5 ENST00000290219.11 ENST00000439213.5 A0A0G2JLE2 |