PLP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	31 studies	33% ± 10%	Explore
CD8-positive, alpha-beta T cell	29 studies	32% ± 15%	Explore
classical monocyte	26 studies	49% ± 19%	Explore
plasmacytoid dendritic cell	26 studies	77% ± 18%	Explore
CD4-positive, alpha-beta T cell	25 studies	42% ± 16%	Explore
T cell	23 studies	34% ± 12%	Explore
conventional dendritic cell	23 studies	45% ± 21%	Explore
fibroblast	21 studies	27% ± 12%	Explore
regulatory T cell	21 studies	40% ± 14%	Explore
smooth muscle cell	20 studies	29% ± 11%	Explore
memory B cell	20 studies	40% ± 13%	Explore
basal cell	20 studies	47% ± 20%	Explore
monocyte	16 studies	39% ± 16%	Explore
natural killer cell	16 studies	30% ± 14%	Explore
mast cell	15 studies	29% ± 6%	Explore
plasma cell	15 studies	45% ± 15%	Explore
naive B cell	15 studies	27% ± 9%	Explore
non-classical monocyte	15 studies	32% ± 14%	Explore
epithelial cell	15 studies	40% ± 17%	Explore
gamma-delta T cell	14 studies	29% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	34% ± 11%	Explore
dendritic cell	12 studies	54% ± 22%	Explore
macrophage	12 studies	26% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	36% ± 10%	Explore
pericyte	12 studies	31% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	32% ± 11%	Explore
ciliated cell	11 studies	41% ± 15%	Explore
mature NK T cell	10 studies	29% ± 13%	Explore
mucosal invariant T cell	10 studies	34% ± 5%	Explore
myeloid cell	9 studies	45% ± 24%	Explore
endothelial cell of lymphatic vessel	9 studies	26% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	46% ± 12%	Explore
type I pneumocyte	8 studies	40% ± 13%	Explore
plasmablast	8 studies	46% ± 20%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	27% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	32% ± 5%	Explore
goblet cell	8 studies	36% ± 19%	Explore
endothelial cell	8 studies	22% ± 6%	Explore
neutrophil	7 studies	36% ± 20%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	34% ± 11%	Explore
mesothelial cell	7 studies	47% ± 21%	Explore
abnormal cell	7 studies	42% ± 15%	Explore
innate lymphoid cell	7 studies	25% ± 7%	Explore
leukocyte	6 studies	28% ± 9%	Explore
IgA plasma cell	6 studies	25% ± 7%	Explore
transit amplifying cell	6 studies	38% ± 22%	Explore
myofibroblast cell	6 studies	31% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	51% ± 22%	Explore
endothelial cell of vascular tree	6 studies	24% ± 7%	Explore
hematopoietic precursor cell	5 studies	49% ± 19%	Explore
exhausted T cell	5 studies	37% ± 13%	Explore
intestinal crypt stem cell	5 studies	25% ± 8%	Explore
hematopoietic stem cell	5 studies	23% ± 4%	Explore
connective tissue cell	5 studies	27% ± 2%	Explore
type II pneumocyte	5 studies	34% ± 16%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	53% ± 13%	Explore
T follicular helper cell	5 studies	30% ± 8%	Explore
CD4-positive helper T cell	4 studies	33% ± 8%	Explore
pancreatic A cell	4 studies	64% ± 20%	Explore
type B pancreatic cell	4 studies	49% ± 17%	Explore
IgG plasma cell	4 studies	24% ± 8%	Explore
adventitial cell	4 studies	32% ± 6%	Explore
intermediate monocyte	4 studies	49% ± 23%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	19% ± 3%	Explore
alveolar macrophage	3 studies	17% ± 1%	Explore
pancreatic D cell	3 studies	54% ± 25%	Explore
megakaryocyte	3 studies	24% ± 4%	Explore
progenitor cell	3 studies	35% ± 10%	Explore
club cell	3 studies	29% ± 9%	Explore
immature B cell	3 studies	34% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	20% ± 3%	Explore
myoepithelial cell	3 studies	55% ± 14%	Explore
acinar cell	3 studies	46% ± 14%	Explore
pancreatic ductal cell	3 studies	49% ± 7%	Explore
granulocyte	3 studies	45% ± 24%	Explore
enteroendocrine cell	3 studies	36% ± 18%	Explore
keratinocyte	3 studies	68% ± 10%	Explore
secretory cell	3 studies	46% ± 10%	Explore
T-helper 17 cell	3 studies	47% ± 11%	Explore
mononuclear phagocyte	3 studies	25% ± 3%	Explore
T-helper 1 cell	3 studies	50% ± 7%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	42% ± 15%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	42% ± 15%	Explore
double negative thymocyte	3 studies	29% ± 3%	Explore
erythrocyte	3 studies	29% ± 12%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	39% ± 9%	Explore
lung	16 studies	30% ± 10%	Explore
intestine	7 studies	23% ± 6%	Explore
lymph node	6 studies	25% ± 7%	Explore
pancreas	4 studies	56% ± 19%	Explore
bone marrow	4 studies	27% ± 10%	Explore
uterus	4 studies	30% ± 9%	Explore
breast	4 studies	24% ± 6%	Explore
kidney	3 studies	31% ± 9%	Explore
esophagus	3 studies	51% ± 24%	Explore
liver	3 studies	31% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	10436.95	1445 / 1445	99%	503.67	182 / 183
intestine	100%	6725.71	965 / 966	99%	411.09	523 / 527
ovary	100%	4785.72	180 / 180	98%	355.42	421 / 430
uterus	100%	7305.32	170 / 170	98%	419.24	448 / 459
breast	99%	4845.01	456 / 459	98%	210.20	1092 / 1118
bladder	100%	8439.33	21 / 21	96%	323.74	486 / 504
lung	99%	5692.90	572 / 578	97%	298.68	1120 / 1155
adrenal gland	100%	8590.89	258 / 258	96%	200.79	220 / 230
pancreas	98%	6533.41	322 / 328	97%	213.29	173 / 178
skin	100%	13535.96	1809 / 1809	92%	235.88	436 / 472
stomach	92%	4332.36	329 / 359	98%	407.65	281 / 286
thymus	82%	2154.84	535 / 653	87%	121.05	525 / 605
prostate	99%	4717.96	242 / 245	54%	41.48	269 / 502
kidney	63%	2295.60	56 / 89	75%	104.06	675 / 901
tonsil	0%	0	0 / 0	100%	494.33	45 / 45
ureter	0%	0	0 / 0	100%	117.81	1 / 1
blood vessel	100%	11986.38	1334 / 1335	0%	0	0 / 0
adipose	99%	4866.41	1196 / 1204	0%	0	0 / 0
peripheral blood	99%	15849.02	920 / 929	0%	0	0 / 0
spleen	96%	3551.66	232 / 241	0%	0	0 / 0
heart	87%	3404.69	748 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	86%	111.30	25 / 29
muscle	71%	2379.32	568 / 803	0%	0	0 / 0
liver	22%	578.90	50 / 226	32%	51.64	130 / 406
eye	0%	0	0 / 0	51%	43.79	41 / 80
brain	4%	82.28	103 / 2642	30%	46.14	215 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0006811	Biological process	monoatomic ion transport
GO_0019221	Biological process	cytokine-mediated signaling pathway
GO_0006935	Biological process	chemotaxis
GO_0005783	Cellular component	endoplasmic reticulum
GO_0016020	Cellular component	membrane
GO_0005886	Cellular component	plasma membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0015075	Molecular function	monoatomic ion transmembrane transporter activity
GO_0005515	Molecular function	protein binding
GO_0019956	Molecular function	chemokine binding

Gene name	PLP2
Protein name	Proteolipid protein 2 (Differentiation-dependent protein A4) (Intestinal membrane A4 protein)
Synonyms	A4
Description	FUNCTION: May play a role in cell differentiation in the intestinal epithelium.
Accessions	ENST00000376327.6 [Q04941-1] Q04941 ENST00000376322.7 [Q04941-2]

PLP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review