IL1F10 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of IL1F10 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of IL1F10 at tissue level.

III. Associated gene sets

GO_0071222Biological processcellular response to lipopolysaccharide
GO_0019221Biological processcytokine-mediated signaling pathway
GO_0010628Biological processpositive regulation of gene expression
GO_0002437Biological processinflammatory response to antigenic stimulus
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0005125Molecular functioncytokine activity
GO_0005149Molecular functioninterleukin-1 receptor binding

IV. Literature review

[source]
Gene nameIL1F10
Protein nameInterleukin-1 family member 10 (IL-1F10) (Family of interleukin 1-theta) (FIL1 theta) (Interleukin-1 HY2) (IL-1HY2) (Interleukin-1 theta) (IL-1 theta) (Interleukin-38) (IL-38)
SynonymsIL1HY2
IL38
UNQ6119/PRO20041
FIL1T
FKSG75
DescriptionFUNCTION: Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2. .

AccessionsQ8WWZ1
ENST00000341010.6 [Q8WWZ1-1]
ENST00000393197.3 [Q8WWZ1-1]