IL12RB2 | OmnibusX

Name	Number of supported studies	Average coverage
CD16-negative, CD56-bright natural killer cell, human	5 studies	23% ± 4%	Explore
natural killer cell	4 studies	22% ± 5%	Explore
macrophage	4 studies	27% ± 7%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of IL12RB2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	78%	78.33	1416 / 1809	86%	34.76	407 / 472
lung	92%	85.86	529 / 578	40%	3.18	458 / 1155
esophagus	69%	69.05	1000 / 1445	53%	8.35	97 / 183
breast	92%	65.32	422 / 459	26%	4.11	296 / 1118
pancreas	100%	283.93	328 / 328	8%	0.69	14 / 178
kidney	69%	51.44	61 / 89	38%	8.87	341 / 901
uterus	45%	17.66	76 / 170	56%	7.86	255 / 459
spleen	100%	143.39	241 / 241	0%	0	0 / 0
muscle	100%	414.71	801 / 803	0%	0	0 / 0
adipose	97%	123.73	1168 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	17.01	40 / 45
intestine	75%	44.12	728 / 966	10%	0.40	51 / 527
liver	79%	35.90	178 / 226	6%	0.33	23 / 406
bladder	62%	25.52	13 / 21	22%	1.99	113 / 504
peripheral blood	80%	367.60	745 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	73%	16.80	58 / 80
stomach	53%	23.67	191 / 359	17%	0.70	48 / 286
thymus	65%	31.28	422 / 653	3%	0.45	18 / 605
blood vessel	68%	39.42	902 / 1335	0%	0	0 / 0
adrenal gland	59%	26.77	152 / 258	1%	0.04	3 / 230
brain	41%	68.61	1085 / 2642	7%	0.28	52 / 705
lymph node	0%	0	0 / 0	41%	2.82	12 / 29
prostate	39%	16.51	95 / 245	1%	0.02	3 / 502
ovary	23%	10.17	42 / 180	10%	0.52	45 / 430
heart	30%	11.28	258 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0019221	Biological process	cytokine-mediated signaling pathway
GO_0032729	Biological process	positive regulation of type II interferon production
GO_0032496	Biological process	response to lipopolysaccharide
GO_0035722	Biological process	interleukin-12-mediated signaling pathway
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0009897	Cellular component	external side of plasma membrane
GO_0043235	Cellular component	receptor complex
GO_0005886	Cellular component	plasma membrane
GO_0015026	Molecular function	coreceptor activity
GO_0019955	Molecular function	cytokine binding
GO_0019901	Molecular function	protein kinase binding
GO_0004896	Molecular function	cytokine receptor activity

Gene name	IL12RB2
Protein name	Interleukin 12 receptor subunit beta 2 Interleukin-12 receptor subunit beta-2 (IL-12 receptor subunit beta-2) (IL-12R subunit beta-2) (IL-12R-beta-2) (IL-12RB2)
Synonyms
Description	FUNCTION: Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Accessions	ENST00000696755.1 ENST00000696754.1 ENST00000696757.1 [Q99665-2] A0A8Q3SIS8 ENST00000696761.1 H0Y5V0 A0A0A0MTN7 ENST00000696758.1 A0A8Q3SJ07 ENST00000441640.4 ENST00000648487.1 [Q99665-1] ENST00000262345.5 [Q99665-1] ENST00000674203.2 [Q99665-1] ENST00000544434.5 [Q99665-3] Q99665 A0A8Q3SIT5 ENST00000696759.1 ENST00000541374.6 ENST00000371000.5 [Q99665-2] A0A8Q3SIX0

IL12RB2 report