Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 26 studies | 53% ± 20% | |
| monocyte | 21 studies | 40% ± 14% | |
| neutrophil | 17 studies | 67% ± 22% | |
| conventional dendritic cell | 16 studies | 32% ± 16% | |
| macrophage | 16 studies | 24% ± 10% | |
| non-classical monocyte | 14 studies | 25% ± 9% | |
| microglial cell | 14 studies | 41% ± 16% | |
| myeloid cell | 11 studies | 34% ± 16% | |
| type II pneumocyte | 10 studies | 49% ± 19% | |
| dendritic cell | 10 studies | 28% ± 14% | |
| hematopoietic precursor cell | 5 studies | 35% ± 22% | |
| hematopoietic stem cell | 5 studies | 40% ± 13% | |
| placental villous trophoblast | 3 studies | 69% ± 10% | |
| common myeloid progenitor | 3 studies | 47% ± 14% | |
| intermediate monocyte | 3 studies | 58% ± 19% | |
| mononuclear phagocyte | 3 studies | 30% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 21266.05 | 578 / 578 | 89% | 15.94 | 1030 / 1155 |
| breast | 82% | 2019.79 | 377 / 459 | 92% | 13.22 | 1027 / 1118 |
| kidney | 60% | 967.69 | 53 / 89 | 83% | 7.09 | 750 / 901 |
| brain | 36% | 551.54 | 947 / 2642 | 93% | 10.33 | 658 / 705 |
| bladder | 57% | 1573.62 | 12 / 21 | 60% | 6.49 | 302 / 504 |
| liver | 78% | 1592.17 | 177 / 226 | 29% | 1.93 | 116 / 406 |
| stomach | 35% | 968.27 | 124 / 359 | 70% | 5.68 | 199 / 286 |
| thymus | 50% | 742.70 | 328 / 653 | 51% | 1.96 | 311 / 605 |
| spleen | 100% | 49909.09 | 241 / 241 | 0% | 0 | 0 / 0 |
| intestine | 41% | 716.72 | 393 / 966 | 57% | 4.08 | 298 / 527 |
| pancreas | 14% | 229.28 | 45 / 328 | 80% | 7.01 | 143 / 178 |
| adrenal gland | 61% | 734.91 | 158 / 258 | 31% | 1.42 | 72 / 230 |
| ovary | 15% | 243.21 | 27 / 180 | 75% | 7.65 | 323 / 430 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 12.62 | 26 / 29 |
| adipose | 89% | 3082.15 | 1075 / 1204 | 0% | 0 | 0 / 0 |
| prostate | 60% | 1025.69 | 146 / 245 | 28% | 0.94 | 141 / 502 |
| uterus | 35% | 684.09 | 59 / 170 | 53% | 3.28 | 242 / 459 |
| peripheral blood | 81% | 262224.95 | 755 / 929 | 0% | 0 | 0 / 0 |
| esophagus | 26% | 452.81 | 377 / 1445 | 55% | 3.10 | 100 / 183 |
| skin | 3% | 32.96 | 48 / 1809 | 60% | 3.69 | 283 / 472 |
| heart | 61% | 1123.78 | 525 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 53% | 2.52 | 24 / 45 |
| blood vessel | 37% | 723.10 | 498 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 14% | 0.35 | 11 / 80 |
| muscle | 7% | 77.41 | 60 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0019221 | Biological process | cytokine-mediated signaling pathway |
| GO_0030593 | Biological process | neutrophil chemotaxis |
| GO_0007155 | Biological process | cell adhesion |
| GO_0097186 | Biological process | amelogenesis |
| GO_0045637 | Biological process | regulation of myeloid cell differentiation |
| GO_0006952 | Biological process | defense response |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0043235 | Cellular component | receptor complex |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030666 | Cellular component | endocytic vesicle membrane |
| GO_0019955 | Molecular function | cytokine binding |
| GO_0038023 | Molecular function | signaling receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004896 | Molecular function | cytokine receptor activity |
| GO_0051916 | Molecular function | granulocyte colony-stimulating factor binding |
| Gene name | CSF3R |
| Protein name | Granulocyte colony-stimulating factor receptor (G-CSF receptor) (G-CSF-R) (CD antigen CD114) Colony stimulating factor 3 receptor |
| Synonyms | GCSFR |
| Description | FUNCTION: Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. . |
| Accessions | ENST00000533491.2 A0A8V8TP76 Q99062 ENST00000373104.5 [Q99062-4] ENST00000373103.5 [Q99062-3] ENST00000699090.1 H0YE86 ENST00000487540.7 ENST00000464465.7 A0A8V8TNA4 E9PK56 ENST00000373106.6 [Q99062-1] |