Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 30 studies | 33% ± 15% | |
conventional dendritic cell | 25 studies | 37% ± 12% | |
dendritic cell | 24 studies | 50% ± 21% | |
classical monocyte | 15 studies | 26% ± 10% | |
monocyte | 14 studies | 27% ± 12% | |
myeloid cell | 12 studies | 34% ± 9% | |
plasmacytoid dendritic cell | 11 studies | 29% ± 12% | |
microglial cell | 10 studies | 47% ± 17% | |
mononuclear phagocyte | 7 studies | 34% ± 12% | |
non-classical monocyte | 6 studies | 22% ± 5% | |
leukocyte | 4 studies | 34% ± 21% | |
monocyte-derived dendritic cell | 4 studies | 63% ± 22% | |
placental villous trophoblast | 3 studies | 45% ± 7% | |
tissue-resident macrophage | 3 studies | 36% ± 12% | |
neutrophil | 3 studies | 22% ± 5% | |
alveolar macrophage | 3 studies | 33% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 1267.88 | 578 / 578 | 90% | 11.09 | 1045 / 1155 |
breast | 95% | 650.81 | 436 / 459 | 93% | 8.70 | 1045 / 1118 |
kidney | 67% | 185.97 | 60 / 89 | 91% | 9.97 | 823 / 901 |
brain | 59% | 225.18 | 1567 / 2642 | 98% | 18.20 | 691 / 705 |
intestine | 83% | 226.76 | 798 / 966 | 72% | 4.98 | 381 / 527 |
thymus | 67% | 152.78 | 439 / 653 | 78% | 5.62 | 474 / 605 |
bladder | 67% | 165.29 | 14 / 21 | 69% | 6.53 | 346 / 504 |
prostate | 72% | 177.14 | 177 / 245 | 63% | 2.77 | 316 / 502 |
adrenal gland | 85% | 234.99 | 220 / 258 | 49% | 2.09 | 113 / 230 |
skin | 55% | 122.86 | 1003 / 1809 | 79% | 12.92 | 372 / 472 |
esophagus | 48% | 100.76 | 692 / 1445 | 78% | 4.72 | 143 / 183 |
stomach | 41% | 86.45 | 147 / 359 | 81% | 6.22 | 232 / 286 |
uterus | 36% | 64.78 | 61 / 170 | 73% | 6.14 | 337 / 459 |
pancreas | 16% | 36.27 | 52 / 328 | 90% | 10.82 | 160 / 178 |
lymph node | 0% | 0 | 0 / 0 | 100% | 20.70 | 29 / 29 |
spleen | 100% | 1303.14 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 98% | 861.70 | 1184 / 1204 | 0% | 0 | 0 / 0 |
ovary | 22% | 36.40 | 39 / 180 | 74% | 4.60 | 317 / 430 |
tonsil | 0% | 0 | 0 / 0 | 91% | 8.71 | 41 / 45 |
peripheral blood | 81% | 5384.54 | 757 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 72% | 238.26 | 967 / 1335 | 0% | 0 | 0 / 0 |
liver | 25% | 51.94 | 56 / 226 | 45% | 2.76 | 181 / 406 |
eye | 0% | 0 | 0 / 0 | 44% | 3.06 | 35 / 80 |
heart | 30% | 59.92 | 261 / 861 | 0% | 0 | 0 / 0 |
muscle | 2% | 2.96 | 14 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0019221 | Biological process | cytokine-mediated signaling pathway |
GO_0070665 | Biological process | positive regulation of leukocyte proliferation |
GO_0038157 | Biological process | granulocyte-macrophage colony-stimulating factor signaling pathway |
GO_0007259 | Biological process | cell surface receptor signaling pathway via JAK-STAT |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0043235 | Cellular component | receptor complex |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0030526 | Cellular component | granulocyte macrophage colony-stimulating factor receptor complex |
GO_0019955 | Molecular function | cytokine binding |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0005515 | Molecular function | protein binding |
GO_0004896 | Molecular function | cytokine receptor activity |
Gene name | CSF2RA |
Protein name | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (GM-CSF-R-alpha) (GMCSFR-alpha) (GMR-alpha) (CDw116) (CD antigen CD116) GM-CSF receptor alpha subunit Colony stimulating factor 2 receptor subunit alpha Colony stimulating factor 2 receptor alpha subunit |
Synonyms | CSF2RY CSF2R |
Description | FUNCTION: Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. |
Accessions | ENST00000696230.1 Q16498 ENST00000355805.7 [P15509-6] ENST00000412290.6 ENST00000381524.8 [P15509-1] ENST00000711226.1 [P15509-3] ENST00000711130.1 ENST00000711221.1 A0A1B4XX95 ENST00000711220.1 [P15509-2] ENST00000711224.1 [P15509-6] ENST00000711225.1 ENST00000711138.1 [P15509-7] A0A8Q3SIC6 ENST00000711135.1 ENST00000711129.1 [P15509-1] ENST00000711131.1 [P15509-1] ENST00000486791.6 V9GYE9 ENST00000432318.8 [P15509-1] ENST00000498153.7 [P15509-7] J3JS74 F2Z3C9 ENST00000711223.1 [P15509-5] ENST00000711137.1 [P15509-1] ENST00000381529.9 [P15509-1] ENST00000355432.8 [P15509-5] ENST00000381500.6 [P15509-3] ENST00000494969.7 ENST00000381509.8 [P15509-2] P15509 |