Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | CSF2-CSF2RA+CSF2RB | CSF2_HUMAN - | Ligand-Receptor | Signaling by Colony-Stimulating factor |
| Name | granulocyte-macrophage colony-stimulating factor signaling pathway |
| ID | GO_0038157 |
| collection_id | Biological process |
| Exact synonym | CSF2 signaling pathway, GM-CSF receptor signaling pathway, GM-CSF signaling pathway, granulocyte-macrophage colony-stimulating factor receptor signaling pathway |
| Description | The series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors. |
| Related synonym | granulocyte-macrophage colony-stimulating factor signalling pathway |
| External URL | |
| Genes |