Insufficient scRNA-seq data for expression of CSF2 at single-cell level.
Insufficient scRNA-seq data for expression of CSF2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 81% | 45.67 | 466 / 578 | 62% | 5.67 | 717 / 1155 |
pancreas | 4% | 0.15 | 12 / 328 | 74% | 5.48 | 132 / 178 |
thymus | 10% | 0.65 | 66 / 653 | 63% | 4.69 | 382 / 605 |
intestine | 17% | 1.94 | 167 / 966 | 54% | 3.17 | 282 / 527 |
bladder | 14% | 0.95 | 3 / 21 | 51% | 4.64 | 259 / 504 |
esophagus | 7% | 0.52 | 103 / 1445 | 57% | 4.70 | 104 / 183 |
tonsil | 0% | 0 | 0 / 0 | 62% | 4.77 | 28 / 45 |
stomach | 8% | 0.60 | 30 / 359 | 53% | 2.78 | 151 / 286 |
uterus | 3% | 0.36 | 5 / 170 | 44% | 3.41 | 202 / 459 |
spleen | 41% | 5.87 | 99 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 38% | 2.78 | 11 / 29 |
skin | 21% | 3.74 | 386 / 1809 | 13% | 0.40 | 60 / 472 |
peripheral blood | 33% | 4.00 | 304 / 929 | 0% | 0 | 0 / 0 |
liver | 16% | 1.09 | 37 / 226 | 2% | 0.05 | 8 / 406 |
kidney | 16% | 1.36 | 14 / 89 | 2% | 0.08 | 19 / 901 |
adipose | 14% | 1.01 | 172 / 1204 | 0% | 0 | 0 / 0 |
breast | 7% | 0.45 | 31 / 459 | 5% | 0.13 | 53 / 1118 |
blood vessel | 11% | 1.22 | 145 / 1335 | 0% | 0 | 0 / 0 |
prostate | 10% | 0.51 | 24 / 245 | 1% | 0.02 | 3 / 502 |
ovary | 3% | 0.16 | 5 / 180 | 4% | 0.11 | 16 / 430 |
adrenal gland | 0% | 0.01 | 1 / 258 | 3% | 0.08 | 7 / 230 |
heart | 3% | 0.32 | 29 / 861 | 0% | 0 | 0 / 0 |
brain | 1% | 0.04 | 17 / 2642 | 1% | 0.04 | 9 / 705 |
muscle | 1% | 0.05 | 9 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0010744 | Biological process | positive regulation of macrophage derived foam cell differentiation |
GO_0042531 | Biological process | positive regulation of tyrosine phosphorylation of STAT protein |
GO_0071803 | Biological process | positive regulation of podosome assembly |
GO_0008283 | Biological process | cell population proliferation |
GO_0030223 | Biological process | neutrophil differentiation |
GO_0001892 | Biological process | embryonic placenta development |
GO_0001821 | Biological process | histamine secretion |
GO_0030225 | Biological process | macrophage differentiation |
GO_0032747 | Biological process | positive regulation of interleukin-23 production |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0034405 | Biological process | response to fluid shear stress |
GO_0097028 | Biological process | dendritic cell differentiation |
GO_0097011 | Biological process | cellular response to granulocyte macrophage colony-stimulating factor stimulus |
GO_0042045 | Biological process | epithelial fluid transport |
GO_0006955 | Biological process | immune response |
GO_0030099 | Biological process | myeloid cell differentiation |
GO_0030335 | Biological process | positive regulation of cell migration |
GO_0043011 | Biological process | myeloid dendritic cell differentiation |
GO_0071222 | Biological process | cellular response to lipopolysaccharide |
GO_0045187 | Biological process | regulation of circadian sleep/wake cycle, sleep |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_2001240 | Biological process | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
GO_0070665 | Biological process | positive regulation of leukocyte proliferation |
GO_0034021 | Biological process | response to silicon dioxide |
GO_0030224 | Biological process | monocyte differentiation |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0038157 | Biological process | granulocyte-macrophage colony-stimulating factor signaling pathway |
GO_0007259 | Biological process | cell surface receptor signaling pathway via JAK-STAT |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0030526 | Cellular component | granulocyte macrophage colony-stimulating factor receptor complex |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005129 | Molecular function | granulocyte macrophage colony-stimulating factor receptor binding |
GO_0008083 | Molecular function | growth factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0005125 | Molecular function | cytokine activity |
Gene name | CSF2 |
Protein name | Granulocyte-macrophage colony-stimulating factor (GM-CSF) (Colony-stimulating factor) (CSF) (Molgramostin) (Sargramostim) |
Synonyms | GMCSF |
Description | FUNCTION: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. . |
Accessions | P04141 ENST00000296871.4 |