Name | Number of supported studies | Average coverage | |
---|---|---|---|
adipocyte | 9 studies | 30% ± 9% | |
hematopoietic precursor cell | 4 studies | 30% ± 11% | |
non-classical monocyte | 4 studies | 20% ± 7% | |
macrophage | 4 studies | 21% ± 3% | |
CD4-positive, alpha-beta T cell | 3 studies | 25% ± 9% | |
classical monocyte | 3 studies | 23% ± 5% | |
regulatory T cell | 3 studies | 18% ± 3% | |
hematopoietic stem cell | 3 studies | 27% ± 11% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 63% ± 9% | |
erythroblast | 3 studies | 37% ± 17% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 2745.63 | 651 / 653 | 100% | 29.30 | 602 / 605 |
breast | 100% | 9295.95 | 459 / 459 | 98% | 30.30 | 1101 / 1118 |
intestine | 100% | 4044.44 | 966 / 966 | 97% | 20.03 | 513 / 527 |
uterus | 100% | 3726.62 | 170 / 170 | 97% | 24.98 | 445 / 459 |
kidney | 100% | 2387.47 | 89 / 89 | 97% | 18.77 | 872 / 901 |
prostate | 100% | 3047.66 | 244 / 245 | 95% | 12.93 | 479 / 502 |
lung | 100% | 4450.46 | 578 / 578 | 95% | 16.64 | 1095 / 1155 |
bladder | 100% | 4305.95 | 21 / 21 | 95% | 18.79 | 477 / 504 |
stomach | 95% | 2203.15 | 340 / 359 | 98% | 20.76 | 279 / 286 |
adrenal gland | 100% | 7221.71 | 258 / 258 | 92% | 17.64 | 212 / 230 |
skin | 92% | 2508.22 | 1662 / 1809 | 99% | 54.52 | 469 / 472 |
esophagus | 99% | 2945.54 | 1431 / 1445 | 92% | 16.09 | 168 / 183 |
ovary | 100% | 3855.73 | 180 / 180 | 90% | 13.97 | 387 / 430 |
pancreas | 85% | 1246.57 | 280 / 328 | 99% | 25.38 | 176 / 178 |
liver | 48% | 523.36 | 109 / 226 | 74% | 7.85 | 299 / 406 |
brain | 41% | 460.47 | 1077 / 2642 | 80% | 10.76 | 561 / 705 |
adipose | 100% | 10425.02 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 76.69 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 76.07 | 29 / 29 |
spleen | 100% | 5579.24 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 31.86 | 45 / 45 |
blood vessel | 100% | 3329.66 | 1334 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 6421.76 | 917 / 929 | 0% | 0 | 0 / 0 |
muscle | 98% | 2556.18 | 788 / 803 | 0% | 0 | 0 / 0 |
heart | 94% | 1577.44 | 807 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0019221 | Biological process | cytokine-mediated signaling pathway |
GO_0038110 | Biological process | interleukin-2-mediated signaling pathway |
GO_0038113 | Biological process | interleukin-9-mediated signaling pathway |
GO_0038156 | Biological process | interleukin-3-mediated signaling pathway |
GO_0035723 | Biological process | interleukin-15-mediated signaling pathway |
GO_0043434 | Biological process | response to peptide hormone |
GO_0038043 | Biological process | interleukin-5-mediated signaling pathway |
GO_0043536 | Biological process | positive regulation of blood vessel endothelial cell migration |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0060397 | Biological process | growth hormone receptor signaling pathway via JAK-STAT |
GO_0030222 | Biological process | eosinophil differentiation |
GO_0040014 | Biological process | regulation of multicellular organism growth |
GO_0035771 | Biological process | interleukin-4-mediated signaling pathway |
GO_0019530 | Biological process | taurine metabolic process |
GO_0001938 | Biological process | positive regulation of endothelial cell proliferation |
GO_0038026 | Biological process | reelin-mediated signaling pathway |
GO_0007595 | Biological process | lactation |
GO_0007259 | Biological process | cell surface receptor signaling pathway via JAK-STAT |
GO_0042127 | Biological process | regulation of cell population proliferation |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006952 | Biological process | defense response |
GO_0005654 | Cellular component | nucleoplasm |
GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0140297 | Molecular function | DNA-binding transcription factor binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | STAT5A |
Protein name | Signal transducer and activator of transcription 5A Signal transducer and activator of transcription |
Synonyms | hCG_16573 STAT5 |
Description | FUNCTION: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. . |
Accessions | ENST00000345506.8 [P42229-1] K7EK35 A0A384N5W4 ENST00000546010.6 [P42229-2] ENST00000678903.1 ENST00000588868.5 P42229 K7EIF9 Q8WWS9 A0A7I2YQF1 ENST00000590949.6 [P42229-1] A0A7I2YQY3 ENST00000676631.1 A0A7I2V380 ENST00000677893.1 ENST00000677301.1 [P42229-1] ENST00000676585.1 [P42229-1] ENST00000590726.7 |