Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 20 studies | 26% ± 11% | |
smooth muscle cell | 14 studies | 23% ± 7% | |
endothelial cell | 13 studies | 24% ± 11% | |
ciliated cell | 12 studies | 33% ± 15% | |
pericyte | 10 studies | 23% ± 7% | |
connective tissue cell | 9 studies | 26% ± 7% | |
epithelial cell | 8 studies | 34% ± 16% | |
myofibroblast cell | 7 studies | 22% ± 4% | |
basal cell | 7 studies | 30% ± 13% | |
epithelial cell of proximal tubule | 5 studies | 19% ± 4% | |
type II pneumocyte | 5 studies | 29% ± 13% | |
type I pneumocyte | 4 studies | 30% ± 9% | |
natural killer cell | 4 studies | 17% ± 2% | |
goblet cell | 4 studies | 26% ± 9% | |
plasmacytoid dendritic cell | 4 studies | 21% ± 4% | |
pancreatic A cell | 3 studies | 26% ± 8% | |
classical monocyte | 3 studies | 20% ± 4% | |
non-classical monocyte | 3 studies | 20% ± 3% | |
kidney loop of Henle epithelial cell | 3 studies | 19% ± 3% | |
endothelial cell of artery | 3 studies | 17% ± 2% | |
retinal bipolar neuron | 3 studies | 32% ± 12% | |
extravillous trophoblast | 3 studies | 31% ± 2% | |
placental villous trophoblast | 3 studies | 29% ± 9% | |
retinal cone cell | 3 studies | 50% ± 16% | |
retinal rod cell | 3 studies | 26% ± 10% | |
abnormal cell | 3 studies | 34% ± 12% | |
endothelial cell of vascular tree | 3 studies | 19% ± 1% | |
mesothelial cell | 3 studies | 30% ± 20% | |
neuron | 3 studies | 35% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 1178.38 | 180 / 180 | 100% | 32.28 | 430 / 430 |
uterus | 100% | 1443.89 | 170 / 170 | 100% | 24.58 | 459 / 459 |
brain | 100% | 1917.32 | 2638 / 2642 | 100% | 30.61 | 704 / 705 |
thymus | 100% | 1816.14 | 653 / 653 | 100% | 25.26 | 602 / 605 |
esophagus | 100% | 1609.76 | 1445 / 1445 | 99% | 16.75 | 182 / 183 |
prostate | 100% | 1800.29 | 245 / 245 | 99% | 32.44 | 499 / 502 |
liver | 100% | 1046.99 | 226 / 226 | 99% | 17.21 | 403 / 406 |
kidney | 100% | 1652.65 | 89 / 89 | 99% | 20.47 | 894 / 901 |
adrenal gland | 100% | 1726.11 | 258 / 258 | 99% | 22.78 | 228 / 230 |
bladder | 100% | 1461.67 | 21 / 21 | 99% | 25.95 | 498 / 504 |
intestine | 100% | 1547.52 | 966 / 966 | 98% | 22.55 | 519 / 527 |
lung | 100% | 1353.09 | 576 / 578 | 98% | 19.41 | 1135 / 1155 |
stomach | 100% | 1492.27 | 359 / 359 | 98% | 20.76 | 279 / 286 |
skin | 100% | 1384.37 | 1808 / 1809 | 97% | 17.97 | 460 / 472 |
breast | 100% | 1372.17 | 459 / 459 | 95% | 18.82 | 1059 / 1118 |
pancreas | 100% | 649.74 | 328 / 328 | 94% | 20.47 | 167 / 178 |
adipose | 100% | 1376.38 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 25.20 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 20.65 | 29 / 29 |
spleen | 100% | 978.73 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 23.94 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 45.29 | 1 / 1 |
blood vessel | 100% | 1553.14 | 1333 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 1480.56 | 853 / 861 | 0% | 0 | 0 / 0 |
muscle | 96% | 659.64 | 771 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 94% | 672.54 | 872 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0090200 | Biological process | positive regulation of release of cytochrome c from mitochondria |
GO_0097191 | Biological process | extrinsic apoptotic signaling pathway |
GO_0019221 | Biological process | cytokine-mediated signaling pathway |
GO_0006919 | Biological process | activation of cysteine-type endopeptidase activity involved in apoptotic process |
GO_0033133 | Biological process | positive regulation of glucokinase activity |
GO_0071260 | Biological process | cellular response to mechanical stimulus |
GO_0045582 | Biological process | positive regulation of T cell differentiation |
GO_0045862 | Biological process | positive regulation of proteolysis |
GO_0046031 | Biological process | ADP metabolic process |
GO_0071396 | Biological process | cellular response to lipid |
GO_0006007 | Biological process | glucose catabolic process |
GO_0008625 | Biological process | extrinsic apoptotic signaling pathway via death domain receptors |
GO_0046034 | Biological process | ATP metabolic process |
GO_0045579 | Biological process | positive regulation of B cell differentiation |
GO_0043280 | Biological process | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
GO_0032024 | Biological process | positive regulation of insulin secretion |
GO_0046931 | Biological process | pore complex assembly |
GO_0097202 | Biological process | activation of cysteine-type endopeptidase activity |
GO_0035774 | Biological process | positive regulation of insulin secretion involved in cellular response to glucose stimulus |
GO_2000078 | Biological process | positive regulation of type B pancreatic cell development |
GO_0097193 | Biological process | intrinsic apoptotic signaling pathway |
GO_0050679 | Biological process | positive regulation of epithelial cell proliferation |
GO_0010508 | Biological process | positive regulation of autophagy |
GO_0097192 | Biological process | extrinsic apoptotic signaling pathway in absence of ligand |
GO_0008630 | Biological process | intrinsic apoptotic signaling pathway in response to DNA damage |
GO_0001836 | Biological process | release of cytochrome c from mitochondria |
GO_1902220 | Biological process | positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress |
GO_0006915 | Biological process | apoptotic process |
GO_0046902 | Biological process | regulation of mitochondrial membrane permeability |
GO_0071316 | Biological process | cellular response to nicotine |
GO_0044342 | Biological process | type B pancreatic cell proliferation |
GO_0010918 | Biological process | positive regulation of mitochondrial membrane potential |
GO_0043065 | Biological process | positive regulation of apoptotic process |
GO_0042593 | Biological process | glucose homeostasis |
GO_0071456 | Biological process | cellular response to hypoxia |
GO_0097138 | Cellular component | BAD-BCL-2 complex |
GO_0005739 | Cellular component | mitochondrion |
GO_0005829 | Cellular component | cytosol |
GO_0005741 | Cellular component | mitochondrial outer membrane |
GO_0008289 | Molecular function | lipid binding |
GO_0005543 | Molecular function | phospholipid binding |
GO_0019903 | Molecular function | protein phosphatase binding |
GO_0008656 | Molecular function | cysteine-type endopeptidase activator activity involved in apoptotic process |
GO_0019901 | Molecular function | protein kinase binding |
GO_0005515 | Molecular function | protein binding |
Gene name | BAD |
Protein name | BCL2 associated agonist of cell death Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death) |
Synonyms | BCL2L8 BBC6 |
Description | FUNCTION: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. . |
Accessions | ENST00000544785.1 F5H1R6 A8MXU7 F5H3B1 ENST00000309032.8 Q92934 ENST00000394531.3 ENST00000493798.1 ENST00000394532.7 ENST00000492141.1 F5GYS3 |