Interactors | Protein name | Directionality | Classification | |
---|---|---|---|---|
1 | TNF-TNFRSF1A | TNFA_HUMAN - TNR1A_HUMAN | Ligand-Receptor | Signaling by Tumor necrosis factor |
2 | TNF-TNFRSF1B | TNFA_HUMAN - TNR1B_HUMAN | Ligand-Receptor | Signaling by Tumor necrosis factor |
Name | intrinsic apoptotic signaling pathway in response to DNA damage |
ID | GO_0008630 |
collection_id | Biological process |
Related synonym | DNA damage response, signal transduction resulting in induction of apoptosis |
Description | The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. |
External URL | |
Genes |