intrinsic apoptotic signaling pathway in response to DNA damage

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1TNF-TNFRSF1ATNFA_HUMAN - TNR1A_HUMANLigand-ReceptorSignaling by Tumor necrosis factor
2TNF-TNFRSF1BTNFA_HUMAN - TNR1B_HUMANLigand-ReceptorSignaling by Tumor necrosis factor

II. Literature review

[source]
Nameintrinsic apoptotic signaling pathway in response to DNA damage
IDGO_0008630
collection_id

Biological process

Related synonym

DNA damage response, signal transduction resulting in induction of apoptosis

Description

The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.

External URL
Genes