BCL2L2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BCL2L2 at tissue level.

III. Associated gene sets

GO_0006919Biological processactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO_0007283Biological processspermatogenesis
GO_0002931Biological processresponse to ischemia
GO_0090201Biological processnegative regulation of release of cytochrome c from mitochondria
GO_0071392Biological processcellular response to estradiol stimulus
GO_1905430Biological processcellular response to glycine
GO_0060011Biological processSertoli cell proliferation
GO_0042981Biological processregulation of apoptotic process
GO_0043066Biological processnegative regulation of apoptotic process
GO_0097192Biological processextrinsic apoptotic signaling pathway in absence of ligand
GO_0008630Biological processintrinsic apoptotic signaling pathway in response to DNA damage
GO_0001836Biological processrelease of cytochrome c from mitochondria
GO_0035795Biological processnegative regulation of mitochondrial membrane permeability
GO_1904646Biological processcellular response to amyloid-beta
GO_0005829Cellular componentcytosol
GO_0005741Cellular componentmitochondrial outer membrane
GO_0097136Cellular componentBcl-2 family protein complex
GO_0044877Molecular functionprotein-containing complex binding
GO_0042802Molecular functionidentical protein binding
GO_0051400Molecular functionBH domain binding
GO_0097718Molecular functiondisordered domain specific binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBCL2L2
Protein nameBCL2 like 2
Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)
SynonymsKIAA0271
BCLW
DescriptionFUNCTION: Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX. .

AccessionsG3V4B7
G3V3G8
Q92843
ENST00000679000.1 [Q92843-1]
ENST00000250405.10 [Q92843-1]
ENST00000678311.1 [Q92843-1]
ENST00000557236.6
ENST00000556100.3 [Q92843-1]
H0YJC7
ENST00000553824.5
ENST00000556599.1
ENST00000557008.2 [Q92843-2]
ENST00000554635.1
G3V3B7
ENST00000553781.5 [Q92843-2]
G3V5A9
ENST00000679219.1 [Q92843-1]
ENST00000557579.2