I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell of vascular tree | 7 studies | 42% ± 11% | |
| vein endothelial cell | 5 studies | 31% ± 16% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell of vascular tree | 7 studies | 42% ± 11% | |
| vein endothelial cell | 5 studies | 31% ± 16% |
Insufficient scRNA-seq data for expression of CSF3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 92% | 7459.30 | 531 / 578 | 51% | 5.52 | 584 / 1155 |
| esophagus | 30% | 308.69 | 439 / 1445 | 77% | 15.63 | 141 / 183 |
| stomach | 36% | 401.50 | 130 / 359 | 66% | 9.25 | 188 / 286 |
| intestine | 32% | 373.54 | 311 / 966 | 64% | 11.78 | 336 / 527 |
| muscle | 87% | 918.32 | 699 / 803 | 0% | 0 | 0 / 0 |
| uterus | 34% | 279.19 | 57 / 170 | 47% | 13.70 | 218 / 459 |
| bladder | 29% | 243.33 | 6 / 21 | 50% | 7.46 | 254 / 504 |
| prostate | 30% | 1002.58 | 73 / 245 | 33% | 2.79 | 167 / 502 |
| tonsil | 0% | 0 | 0 / 0 | 56% | 6.51 | 25 / 45 |
| blood vessel | 44% | 553.59 | 586 / 1335 | 0% | 0 | 0 / 0 |
| brain | 27% | 216.23 | 714 / 2642 | 17% | 1.23 | 118 / 705 |
| adipose | 43% | 1437.98 | 522 / 1204 | 0% | 0 | 0 / 0 |
| breast | 32% | 440.16 | 146 / 459 | 5% | 0.27 | 59 / 1118 |
| skin | 26% | 339.18 | 474 / 1809 | 10% | 1.08 | 48 / 472 |
| thymus | 21% | 254.60 | 135 / 653 | 12% | 0.90 | 75 / 605 |
| heart | 32% | 605.52 | 275 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 4% | 69.19 | 14 / 328 | 20% | 2.55 | 35 / 178 |
| adrenal gland | 11% | 284.52 | 28 / 258 | 11% | 1.94 | 26 / 230 |
| ovary | 14% | 110.54 | 26 / 180 | 6% | 0.25 | 24 / 430 |
| kidney | 15% | 203.53 | 13 / 89 | 3% | 0.25 | 31 / 901 |
| lymph node | 0% | 0 | 0 / 0 | 17% | 4.43 | 5 / 29 |
| spleen | 13% | 42.81 | 31 / 241 | 0% | 0 | 0 / 0 |
| liver | 4% | 16.21 | 8 / 226 | 1% | 0.02 | 5 / 406 |
| peripheral blood | 3% | 59.13 | 25 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0019221 | Biological process | cytokine-mediated signaling pathway |
| GO_0030838 | Biological process | positive regulation of actin filament polymerization |
| GO_0110053 | Biological process | regulation of actin filament organization |
| GO_0045471 | Biological process | response to ethanol |
| GO_0006955 | Biological process | immune response |
| GO_0030851 | Biological process | granulocyte differentiation |
| GO_0071345 | Biological process | cellular response to cytokine stimulus |
| GO_0038158 | Biological process | granulocyte colony-stimulating factor signaling pathway |
| GO_0050731 | Biological process | positive regulation of peptidyl-tyrosine phosphorylation |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0045639 | Biological process | positive regulation of myeloid cell differentiation |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0071682 | Cellular component | endocytic vesicle lumen |
| GO_0043202 | Cellular component | lysosomal lumen |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0005130 | Molecular function | granulocyte colony-stimulating factor receptor binding |
| GO_0008083 | Molecular function | growth factor activity |
| GO_0005125 | Molecular function | cytokine activity |
| Gene name | CSF3 |
| Protein name | Colony stimulating factor 3 (Granulocyte) Colony stimulating factor 3 nirs variant 1 Granulocyte colony-stimulating factor Colony stimulating factor 3 Granulocyte colony-stimulating factor (G-CSF) (Pluripoietin) (Filgrastim) (Lenograstim) |
| Synonyms | C17orf33 hCG_30013 GCSF |
| Description | FUNCTION: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. FUNCTION: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. . FUNCTION: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. . FUNCTION: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. . FUNCTION: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. . FUNCTION: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. . |
| Accessions | ENST00000394148.7 [P09919-3] Q8N4W3 Q5FBY7 P09919 ENST00000579852.1 D7RVA3 ENST00000225474.6 [P09919-1] J3KTH8 ENST00000583218.5 J3QRD4 ENST00000331769.6 ENST00000394149.8 [P09919-2] ENST00000577675.1 Q6FH65 J3QRX2 C3VB11 |
