Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 13 studies | 32% ± 12% | |
| fibroblast | 7 studies | 23% ± 4% | |
| cardiac muscle cell | 4 studies | 31% ± 6% | |
| glial cell | 3 studies | 27% ± 6% | |
| smooth muscle cell | 3 studies | 20% ± 2% | |
| glutamatergic neuron | 3 studies | 21% ± 1% | |
| GABAergic neuron | 3 studies | 23% ± 4% |
Insufficient scRNA-seq data for expression of TNFRSF19 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 98% | 2633.26 | 239 / 245 | 92% | 42.45 | 463 / 502 |
| skin | 92% | 6914.04 | 1671 / 1809 | 93% | 81.31 | 437 / 472 |
| kidney | 97% | 1190.02 | 86 / 89 | 83% | 25.35 | 751 / 901 |
| lung | 97% | 1863.99 | 563 / 578 | 75% | 17.82 | 866 / 1155 |
| esophagus | 85% | 824.19 | 1232 / 1445 | 60% | 13.18 | 110 / 183 |
| breast | 56% | 430.45 | 258 / 459 | 79% | 16.85 | 886 / 1118 |
| ovary | 56% | 360.61 | 100 / 180 | 78% | 17.94 | 335 / 430 |
| uterus | 75% | 711.18 | 127 / 170 | 45% | 15.14 | 205 / 459 |
| thymus | 78% | 522.62 | 508 / 653 | 32% | 4.81 | 196 / 605 |
| bladder | 81% | 922.57 | 17 / 21 | 29% | 7.57 | 146 / 504 |
| pancreas | 26% | 170.70 | 84 / 328 | 77% | 11.01 | 137 / 178 |
| brain | 11% | 62.05 | 285 / 2642 | 88% | 25.62 | 619 / 705 |
| heart | 98% | 2431.92 | 846 / 861 | 0% | 0 | 0 / 0 |
| stomach | 57% | 337.14 | 203 / 359 | 35% | 9.86 | 99 / 286 |
| spleen | 72% | 521.46 | 173 / 241 | 0% | 0 | 0 / 0 |
| intestine | 40% | 256.62 | 386 / 966 | 31% | 6.38 | 164 / 527 |
| adrenal gland | 28% | 172.90 | 71 / 258 | 36% | 4.96 | 83 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 60% | 13.83 | 27 / 45 |
| eye | 0% | 0 | 0 / 0 | 56% | 17.29 | 45 / 80 |
| adipose | 38% | 250.52 | 463 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 36% | 319.25 | 481 / 1335 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 31% | 8.77 | 125 / 406 |
| muscle | 12% | 74.10 | 97 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 12% | 176.76 | 109 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006915 | Biological process | apoptotic process |
| GO_0007254 | Biological process | JNK cascade |
| GO_0043123 | Biological process | positive regulation of canonical NF-kappaB signal transduction |
| GO_0033209 | Biological process | tumor necrosis factor-mediated signaling pathway |
| GO_0001942 | Biological process | hair follicle development |
| GO_0046330 | Biological process | positive regulation of JNK cascade |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005031 | Molecular function | tumor necrosis factor receptor activity |
| GO_0038023 | Molecular function | signaling receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TNFRSF19 |
| Protein name | Tumor necrosis factor receptor superfamily member 19 (TRADE) (Toxicity and JNK inducer) |
| Synonyms | TAJ UNQ1888/PRO4333 TROY |
| Description | FUNCTION: Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death. |
| Accessions | ENST00000382263.3 [Q9NS68-2] ENST00000248484.9 [Q9NS68-2] ENST00000403372.6 [Q9NS68-3] Q9NS68 ENST00000382258.8 [Q9NS68-1] |