CCDC85B | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	40 studies	56% ± 22%	Explore
natural killer cell	34 studies	39% ± 11%	Explore
fibroblast	32 studies	30% ± 12%	Explore
B cell	31 studies	29% ± 9%	Explore
CD8-positive, alpha-beta T cell	31 studies	39% ± 16%	Explore
CD4-positive, alpha-beta T cell	30 studies	34% ± 10%	Explore
pericyte	27 studies	35% ± 19%	Explore
T cell	24 studies	34% ± 10%	Explore
smooth muscle cell	23 studies	32% ± 10%	Explore
conventional dendritic cell	21 studies	29% ± 15%	Explore
regulatory T cell	20 studies	33% ± 11%	Explore
macrophage	18 studies	25% ± 10%	Explore
mature NK T cell	17 studies	38% ± 11%	Explore
memory B cell	17 studies	29% ± 6%	Explore
non-classical monocyte	17 studies	31% ± 16%	Explore
endothelial cell of lymphatic vessel	16 studies	33% ± 9%	Explore
plasmacytoid dendritic cell	16 studies	31% ± 11%	Explore
classical monocyte	16 studies	29% ± 13%	Explore
capillary endothelial cell	16 studies	48% ± 20%	Explore
gamma-delta T cell	16 studies	40% ± 14%	Explore
naive B cell	15 studies	26% ± 6%	Explore
mast cell	14 studies	28% ± 5%	Explore
monocyte	13 studies	26% ± 8%	Explore
myofibroblast cell	13 studies	32% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	39% ± 10%	Explore
mucosal invariant T cell	12 studies	34% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	39% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	32% ± 8%	Explore
endothelial cell of artery	12 studies	59% ± 18%	Explore
vein endothelial cell	12 studies	57% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	45% ± 10%	Explore
connective tissue cell	11 studies	28% ± 10%	Explore
endothelial cell of vascular tree	11 studies	54% ± 17%	Explore
plasma cell	10 studies	31% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	41% ± 15%	Explore
dendritic cell	10 studies	39% ± 24%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	37% ± 17%	Explore
myeloid cell	9 studies	24% ± 11%	Explore
basal cell	8 studies	33% ± 17%	Explore
innate lymphoid cell	7 studies	31% ± 10%	Explore
plasmablast	7 studies	43% ± 19%	Explore
platelet	7 studies	35% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	39% ± 10%	Explore
abnormal cell	7 studies	28% ± 6%	Explore
epithelial cell	7 studies	31% ± 14%	Explore
T follicular helper cell	7 studies	28% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	43% ± 20%	Explore
leukocyte	6 studies	29% ± 8%	Explore
glutamatergic neuron	6 studies	36% ± 21%	Explore
precursor B cell	6 studies	37% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	40% ± 13%	Explore
CD4-positive helper T cell	5 studies	26% ± 10%	Explore
exhausted T cell	5 studies	51% ± 16%	Explore
mononuclear phagocyte	5 studies	29% ± 14%	Explore
neuron	5 studies	32% ± 13%	Explore
amacrine cell	5 studies	36% ± 18%	Explore
hematopoietic stem cell	5 studies	40% ± 11%	Explore
ciliated cell	5 studies	27% ± 7%	Explore
hematopoietic precursor cell	4 studies	43% ± 13%	Explore
glomerular endothelial cell	4 studies	49% ± 14%	Explore
retinal ganglion cell	4 studies	77% ± 18%	Explore
megakaryocyte	4 studies	44% ± 13%	Explore
immature B cell	4 studies	32% ± 5%	Explore
adventitial cell	4 studies	29% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	49% ± 23%	Explore
T-helper 17 cell	4 studies	45% ± 18%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	37% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	29% ± 9%	Explore
progenitor cell	3 studies	42% ± 18%	Explore
retinal bipolar neuron	3 studies	47% ± 10%	Explore
OFF-bipolar cell	3 studies	48% ± 25%	Explore
ON-bipolar cell	3 studies	48% ± 27%	Explore
common myeloid progenitor	3 studies	41% ± 16%	Explore
erythroblast	3 studies	32% ± 9%	Explore
lymphocyte	3 studies	40% ± 15%	Explore
pro-B cell	3 studies	27% ± 4%	Explore
astrocyte	3 studies	33% ± 11%	Explore
retina horizontal cell	3 studies	32% ± 11%	Explore
retinal cone cell	3 studies	70% ± 12%	Explore
retinal rod cell	3 studies	30% ± 6%	Explore
alveolar macrophage	3 studies	18% ± 1%	Explore
intraepithelial lymphocyte	3 studies	42% ± 6%	Explore
germinal center B cell	3 studies	25% ± 5%	Explore
intermediate monocyte	3 studies	44% ± 23%	Explore
GABAergic neuron	3 studies	40% ± 12%	Explore
oligodendrocyte precursor cell	3 studies	26% ± 8%	Explore
granulocyte	3 studies	25% ± 9%	Explore
granulocyte monocyte progenitor cell	3 studies	30% ± 10%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	51% ± 22%	Explore
enteroendocrine cell	3 studies	39% ± 16%	Explore
erythrocyte	3 studies	35% ± 7%	Explore
group 3 innate lymphoid cell	3 studies	36% ± 16%	Explore
keratinocyte	3 studies	26% ± 8%	Explore
T-helper 1 cell	3 studies	52% ± 10%	Explore
progenitor cell of mammary luminal epithelium	3 studies	24% ± 3%	Explore
secretory cell	3 studies	40% ± 20%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	35% ± 10%	Explore
lung	13 studies	27% ± 8%	Explore
brain	7 studies	28% ± 13%	Explore
eye	7 studies	31% ± 11%	Explore
intestine	6 studies	23% ± 8%	Explore
lymph node	5 studies	25% ± 4%	Explore
liver	5 studies	29% ± 10%	Explore
kidney	4 studies	29% ± 5%	Explore
uterus	4 studies	37% ± 8%	Explore
breast	4 studies	29% ± 5%	Explore
bone marrow	3 studies	26% ± 9%	Explore
prostate	3 studies	21% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	2722.07	180 / 180	100%	172.65	430 / 430
brain	100%	6861.87	2631 / 2642	99%	116.67	701 / 705
adrenal gland	100%	2957.06	258 / 258	98%	119.81	226 / 230
esophagus	98%	2785.59	1411 / 1445	100%	109.50	183 / 183
skin	99%	3508.79	1786 / 1809	97%	90.48	459 / 472
uterus	100%	2889.51	170 / 170	95%	78.48	435 / 459
thymus	96%	2279.59	627 / 653	98%	110.39	594 / 605
prostate	98%	2668.07	240 / 245	95%	73.82	477 / 502
bladder	95%	3309.38	20 / 21	97%	98.39	489 / 504
lung	99%	3590.57	572 / 578	92%	56.72	1060 / 1155
intestine	93%	2277.72	899 / 966	97%	119.89	512 / 527
stomach	87%	1738.30	312 / 359	98%	115.17	280 / 286
breast	99%	2889.90	456 / 459	81%	51.39	903 / 1118
kidney	90%	1544.72	80 / 89	86%	54.76	775 / 901
pancreas	67%	791.89	221 / 328	90%	78.25	160 / 178
liver	58%	623.44	132 / 226	82%	37.86	334 / 406
eye	0%	0	0 / 0	100%	175.93	80 / 80
lymph node	0%	0	0 / 0	100%	200.36	29 / 29
spleen	100%	3808.65	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	59.28	45 / 45
ureter	0%	0	0 / 0	100%	264.90	1 / 1
adipose	99%	3476.53	1189 / 1204	0%	0	0 / 0
blood vessel	98%	3526.30	1314 / 1335	0%	0	0 / 0
heart	98%	3203.76	844 / 861	0%	0	0 / 0
muscle	91%	1708.26	732 / 803	0%	0	0 / 0
peripheral blood	82%	1873.02	762 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0045599	Biological process	negative regulation of fat cell differentiation
GO_0030154	Biological process	cell differentiation
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0030308	Biological process	negative regulation of cell growth
GO_0005813	Cellular component	centrosome
GO_0005912	Cellular component	adherens junction
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0070097	Molecular function	delta-catenin binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CCDC85B
Protein name	Coiled-coil domain-containing protein 85B (Hepatitis delta antigen-interacting protein A) (Delta-interacting protein A)
Synonyms	DIPA
Description	FUNCTION: Functions as a transcriptional repressor . May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth . May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (By similarity). Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity). .; FUNCTION: (Microbial infection) Plays a role in hepatitis delta virus (HDV) genomic replication. .
Accessions	ENST00000312579.4 Q15834

CCDC85B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review